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Displaying drugs 601 - 625 of 782 in total
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … 9,10-anthracenedione, 2,7-bis(((3r,5s)-3,5-dimethyl-1-piperidinyl)sulfonyl)-, 9,10-dioxime, rel- …
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … florbetapir-fluorine-18 …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Experimental
Matched Synonyms: … 4-[2,6,8-trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]butyl dihydrogen phosphate
Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).
Investigational
Matched Synonyms: … 3'-thymidylic acid, monobutyl ester, 5'-(butyl hydrogen phosphate) …
Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
Experimental
Matched Synonyms: … Choline, dihydrogen phosphate (ester) (8CI) …
Matched Description: … Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. …
Experimental
Matched Synonyms: … D-glycerate 3-phosphate
Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Synonyms: … Artemisia officinalis root …
Experimental
Matched Synonyms: … β-D-ribofuranose 5-phosphate
Matched Name: … beta-D-Ribose-5-phosphate
5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Experimental
Matched Synonyms: … Uridine phosphate
Matched Description: … A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Methionine Phosphinate
Experimental
Matched Name: … Mercaptomethyl Phosphonate
Matched Iupac: … (sulfanylmethyl)phosphonate
Experimental
Matched Name: … Alpha-Ribazole-5'-Phosphate
Experimental
Matched Name: … 2-Amino-Vinyl-Phosphate
Experimental
Matched Name: … Indole-3-Propanol Phosphate
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Experimental
Matched Name: … Nicotinamide adenine dinucleotide phosphate
Matched Description: … It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ... Nicotinamide adenine dinucleotide phosphate. ... the 5'-phosphate adenosine 2',5'-bisphosphate. …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Indole-3-Glycerol Phosphate
Matched Categories: … Indicators and Reagents ... Sugar Phosphates
Experimental
Matched Name: … DIETHYL 4-METHOXYPHENYL PHOSPHATE
Matched Iupac: … diethyl 4-methoxyphenyl phosphate
Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Approved
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Zopiclone and prodrugs ... Sleep Initiation and Maintenance Disorders ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Septa-zopiclone …
Experimental
Matched Name: … N-Bromoacetyl-Aminoethyl Phosphate
Experimental
Matched Name: … Thymidine-5'-(dithio)phosphate
Experimental
Matched Name: … Adenosine-5'-(Dithio)Phosphate
Experimental
Matched Name: … L-Threonohydroxamate 4-Phosphate
Experimental
Matched Name: … 5-FLUOROINDOLE PROPANOL PHOSPHATE
Displaying drugs 601 - 625 of 782 in total