Displaying drugs 601 - 625 of 1013 in total
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Recombinant human C1-INH ... Recombinant human C1 inhibitor ... Recombinant human C1-inhibitor …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Lecanemab
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …
Matched Description: … recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mirvetuximab
Investigational
Matched Synonyms: … (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a ... Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Zolbetuximab
Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).
Investigational
Matched Synonyms: … immunoglobulin G1, anti-(human Claudin-18.2) (human-mus musculus monoclonal IMAB362 heavy chain), disulfide ... with human-mus musculus monoclonal IMAB362 .kappa. …
Matched Description: … Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Human Umbilical Cord Mesenchymal Stem Cells
Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational
Matched Synonyms: … Human Umbilical Cord Wharton’s Jelly-derived Mesenchymal Stem Cells …
Matched Name: … Human Umbilical Cord Mesenchymal Stem Cells …
Matched Description: … class II and its co-stimulatory ligands like CD40, CD80, and CD86. ... UC mesenchymal cells derived from Wharton’s jelly are the most studied and offer more stable and better ... osteogenic and adipogenic differentiation potentials. …
Matched Name: … Human Umbilical Cord Mesenchymal Stem Cells …
Matched Description: … class II and its co-stimulatory ligands like CD40, CD80, and CD86. ... UC mesenchymal cells derived from Wharton’s jelly are the most studied and offer more stable and better ... osteogenic and adipogenic differentiation potentials. …
Human cord blood hematopoietic progenitor cell
Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures in patients with disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment. Human...
Approved
Matched Name: … Human cord blood hematopoietic progenitor cell …
Matched Description: … lymphocytes, and granulocytes from human cord blood. ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen …
Matched Description: … lymphocytes, and granulocytes from human cord blood. ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen …
Allogeneic human pancreatic islets of Langerhans
Investigational
Matched Name: … Allogeneic human pancreatic islets of Langerhans …
Depemokimab
Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain ... ), disulfide with human-mus musculus monoclonal gsk3511294 .kappa. …
Matched Description: … Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab …
Matched Description: … Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab …
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …
Matched Products: … Cefotaxime and Dextrose …
Zoledronate D,L-Lysine Monohydrate
Approved
Investigational
Matched Name: … Zoledronate D,L-Lysine Monohydrate …
Metelimumab
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4- ... chain)), disulfide with human monoclonal cat-192 .kappa. ... Human anti-transforming growth factor beta 1 monoclonal antibody …
Human ciliary neurotrophic factor, recombinant (E. coli)
Investigational
Matched Synonyms: … Ciliary neurotrophic factor, recombinant human …
Matched Name: … Human ciliary neurotrophic factor, recombinant (E. coli) …
Matched Name: … Human ciliary neurotrophic factor, recombinant (E. coli) …
Hemopexin
Investigational
Matched Synonyms: … HEMOPEXIN (HUMAN) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Recombinant human placental growth factor (PLGF-131)
Investigational
Matched Synonyms: … RECOMBINANT HUMAN PLACENTAL GROWTH FACTOR …
Matched Name: … Recombinant human placental growth factor (PLGF-131) …
Matched Name: … Recombinant human placental growth factor (PLGF-131) …
Amniotic Epithelial Cells
Amniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus.[A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine due to their potential for differentiation and multiplication.
Investigational
Matched Synonyms: … Human Amniotic Epithelial Cells …
Matched Description: … due to their potential for differentiation and multiplication. ... [A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine ... epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human …
Matched Description: … due to their potential for differentiation and multiplication. ... [A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine ... epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human …
Ligufalimab
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma ... .4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa. …
Bepranemab
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 ... .gamma.4-chain), disulfide with human-rattus norvegicus monoclonal ucb0107 .kappa. …
Matched Description: … Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau. …
Matched Description: … Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau. …
Fibrinolysin
Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Fibrinolysin is used as a...
Investigational
Matched Synonyms: … Fibrinolysin, human ... Fibrinolysin (human) …
Matched Description: … Fibrinolysin and deoxyribonuclease both act as lytic enzymes. ... Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. ... The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... fibrinolysin and desoxyribonuclease …
Matched Description: … Fibrinolysin and deoxyribonuclease both act as lytic enzymes. ... Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. ... The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... fibrinolysin and desoxyribonuclease …
Otlertuzumab
Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Recombinant methionyl brain-derived neurotrophic factor
Investigational
Matched Synonyms: … Recombinant methionyl human bdnf ... Recombinant methionyl human brain-derived neurotrophic factor …
Batoclimab
Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational
Matched Synonyms: … Immunoglobulin g1(238-alanine, 239-alanine), anti-(human fcrn receptor) (human monoclonal hl161bkn .gamma ... .1-chain), disulfide with human monoclonal hl161bkn .lambda. …
Matched Description: … Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tafolecimab
Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia).
Investigational
Matched Synonyms: … Immunoglobulin igg2, anti-(human proprotein convertase subtilisin/kexin type 9) (human monoclonal ibi306 ... .gamma.2-chain), disulfide with human monoclonal ibi306 .kappa. …
Matched Description: … Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy …
Matched Description: … Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy …
Human allogeneic bone marrow derived osteoblastic cells
Investigational
Matched Synonyms: … Human allogeneic bone marrow derived osteoblastic cells ... Human allogeneic bone-marrow-derived osteoblastic cells …
Matched Name: … Human allogeneic bone marrow derived osteoblastic cells …
Matched Name: … Human allogeneic bone marrow derived osteoblastic cells …
Andecaliximab
Andecaliximab is a monoclonal antibody directed against matrix metallopeptidase 9 (MMP9). Andecaliximab is under investigation in clinical trial NCT03631836 (Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human gelatinase b) (human-mus musculus monoclonal gs-5745 heavy chain), disulfide ... with human-mus musculus monoclonal gs-5745 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 601 - 625 of 1013 in total