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Displaying drugs 6301 - 6325 of 10948 in total

3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide

Experimental
Matched Name: … 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide …
Matched Iupac: … 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N,N-dimethyl-1-benzofuran-6-sulfonamide …

alpha-Pinene

Experimental
Matched Synonyms: … pin-2(3)-ene ... 2-pinene ... (±)-2-pinene …
Matched Iupac: … 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene …

Propagermanium

Investigational
Matched Synonyms: … 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid ... Bis (2-carboxyethylgermanium)sesquioxide …
Matched Iupac: … bis((2-carboxyethyl)germanetris(ylium)) trioxidandiide …

Gibberellin A4

Experimental
Matched Synonyms: … 2β,4a-dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic acid, 1,4a-lactone …

2,3-Didehydroalanine

Experimental
Matched Iupac: … 2-aminoprop-2-enoic acid …

Carbovir

Investigational
Matched Synonyms: … 6h-purin-6-one, 2-amino-1,9-dihydro-9-((1r,4s)-4-(hydroxymethyl)-2-cyclopenten-1-yl)-, rel- …
Matched Iupac: … 2-amino-9-[(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-6,9-dihydro-1H-purin-6-one …

Cinalukast

Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Experimental
Matched Synonyms: … 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Olenasufligene relduparvovec

Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying …

Tavokinogene telseplasmid

Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational

SB719125

Investigational

3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE

Experimental
Matched Name: … 3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE …
Matched Iupac: … 4,4-bis(4-hydroxyphenyl)-8-nitro-3-oxatricyclo[7.3.1.0^{5,13}]trideca-1(12),5(13),6,8,10-pentaen-2-one …

AGS-499

Investigational

ADX10059

ADX10059 is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). The orally available small molecule drug candidate, which is highly specific for mGluR5, was discovered at Addex in 2003. It is developed for the treatment of GERD, migraine and anxiety.
Investigational
Matched Description: … ADX10059 is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). …

2'-C-methylcytidine

A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
Experimental
Matched Synonyms: … 2'C-Me-C ... 2'-C-Mecytosin …
Matched Name: … 2'-C-methylcytidine …
Matched Iupac: … 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2- …
Matched Description: … Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-Isobutyl-3-methoxypyrazine

Experimental
Matched Synonyms: … 3-Isobutyl-2-methoxypyrazine …
Matched Name: … 2-Isobutyl-3-methoxypyrazine …
Matched Iupac: … 2-methoxy-3-(2-methylpropyl)pyrazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-Oxo-3-Pentenoic Acid

Experimental
Matched Name: … 2-Oxo-3-Pentenoic Acid …
Matched Iupac: … (3Z)-2-oxopent-3-enoic acid …

AP-102

Investigational
Matched Synonyms: … -, cyclic (2->7)-disulfide ... H-(4-amino-3-iodo)-d-phe-c(cys-(3-iodo)-tyr-d-trp-lys-val-cys)-thr-nh2 ... H-(4-amino-3-iodo)-D-Phe-c[Cys-(3-iodo)-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH2 …
Matched Iupac: … (2S,3R)-2-{[(4R,7S,10S,13R,16S,19R)-19-[(2R)-2-amino-3-(4-amino-3-iodophenyl)propanamido]-10-(4-aminobutyl ... )-16-[(4-hydroxy-3-iodophenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2-yl ... )-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]formamido}-3-hydroxybutanamide …

Avotaciclib

Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).
Investigational
Matched Synonyms: … 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol …
Matched Iupac: … 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol …
Matched Salts cas: … 1983984-01-5 …

N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide

Experimental
Matched Name: … N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide …
Matched Iupac: … N,4-dimethyl-3-({1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}amino)benzamide …

Tepilamide fumarate

Investigational
Matched Synonyms: … 2-butenedioic acid (2e)-, 1-(2-(diethylamino)-2-oxoethyl) 4-methyl ester ... 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate ... (n,n-diethylcarbamoyl)methyl methyl (2e)-but-2-ene-1,4-dioate …

Cordycepin Triphosphate

Experimental
Matched Iupac: … ({[({[(2S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE

Experimental
Matched Name: … 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE …
Matched Iupac: … 1-{[(4-chlorophenyl)carbamoyl]methyl}-N-[1-(propan-2-yl)piperidin-4-yl]-1H-indole-2-carboxamide …

Methionine sulfoximine, (S)-

Investigational
Matched Synonyms: … L-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine ... (2s)-2-amino-4-((s(s))-s-methylsulfonimidoyl)butanoic acid ... Butanoic acid, 2-amino-4-((s(s))-s-methylsulfonimidoyl)-, (2s)- …
Matched Iupac: … (2S)-2-amino-4-[(S)-imino(methyl)oxo-lambda6-sulfanyl]butanoic acid …

METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE

Experimental
Matched Name: … METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE …
Matched Iupac: … methyl (2E)-3-methoxy-2-{2-[(1E)-2-phenylethenyl]phenyl}prop-2-enoate …

APD791

APD791 is an oral anti-thrombotic drug candidate being evaluated in a Phase 1 clinical trial by Arena. APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin.
Investigational
Matched Description: … APD791 is an oral anti-thrombotic drug candidate being evaluated in a Phase 1 clinical trial by Arena …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT2 Receptor Antagonists …
Displaying drugs 6301 - 6325 of 10948 in total