Displaying drugs 6326 - 6350 of 9924 in total
Equol
Equol has been used in trials studying the treatment of Breast Cancer.
Investigational
Matched Iupac: … (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol …
Neopterin
Neopterin is under investigation in clinical trial NCT02974192 (Neopterin Effects on Ischemic Stroke).
Investigational
Matched Iupac: … 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-3,4-dihydropteridin-4-one …
Olokizumab
Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome....
Investigational
Matched Description: … Olokizumab is a humanized anti-IL-6 IgG4κ antibody that directly blocks gp130 binding at IL-6 Site 3. …
CI-1040
CI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others.
Investigational
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide …
4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline
Experimental
Matched Name: … 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline …
Matched Iupac: … 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol …
Matched Iupac: … 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol …
(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid …
7-Methylguanosine
Experimental
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5 …
Aspacytarabine
Investigational
Matched Synonyms: … -d-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)- ... -d-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin-4-yl)-l-asparagine …
Matched Iupac: … (2S)-2-amino-3-({1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin ... -4-yl}carbamoyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-({1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin ... -4-yl}carbamoyl)propanoic acid …
AL5424
Experimental
Matched Iupac: … (4R)-4-hydroxy-2-(4-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
AL5300
Experimental
Matched Iupac: … (4R)-4-hydroxy-1,1-dioxo-2-[(thiophen-2-yl)methyl]-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
WVE-N531
Investigational
K-777
Investigational
Matched Synonyms: … 1-piperazinecarboxamide, 4-methyl-n-((1s)-2-oxo-2-(((1s)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen ... 4-methylpiperazine-1-carboxylic acid [1-(3-benzenesufonyl-1-phenethylallyl-carbamoyl)-2-phenylethyl] ... 1-piperazinecarboxamide, 4-methyl-n-((1s)-2-oxo-2-(((1s)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propenyl …
Matched Iupac: … (2S)-N-[(1E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-2-{[(E)-4-methylpiperazine-1-carbonyl]amino ... }-3-phenylpropanamide …
Matched Iupac: … (2S)-N-[(1E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-2-{[(E)-4-methylpiperazine-1-carbonyl]amino ... }-3-phenylpropanamide …
Aminophosphonic acid-guanylate ester
Experimental
Matched Iupac: … {[amino(hydroxy)phosphoryl]oxy}({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan …
(3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE
Experimental
Matched Name: … (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE …
Matched Iupac: … (3E)-2,6-dioxo-6-phenylhex-3-enoate …
Matched Iupac: … (3E)-2,6-dioxo-6-phenylhex-3-enoate …
AZD-3839
AZD3839 has been used in trials studying the basic science of Safety, Tolerability, Alzheimer's Disease, and Blood Concentration.
Investigational
Matched Iupac: … (1S)-1-[2-(difluoromethyl)pyridin-4-yl]-4-fluoro-1-[3-(pyrimidin-5-yl)phenyl]-1H-isoindol-3-amine …
Odanacatib
Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis . The drug made it to phase III trials before abandoned due to increased stroke.
Investigational
Matched Iupac: … (2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-{[(1S)-2,2,2-trifluoro-1-{4'-methanesulfonyl-[1,1'-biphenyl ... ]-4-yl}ethyl]amino}pentanamide …
Telapristone acetate
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Synonyms: … 17alpha-Acetoxy-11beta-(4-(dimethylamino)phenyl)-21-methoxy-19-norpregna-4,9-dien-3,20-dione …
Matched Iupac: … (1R,3aS,3bS,10R,11aS)-10-[4-(dimethylamino)phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH, …
Matched Iupac: … (1R,3aS,3bS,10R,11aS)-10-[4-(dimethylamino)phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH, …
2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile
Experimental
Matched Name: … 2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene ... ]amino}-3-methylbenzonitrile …
Matched Iupac: … 4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)-hexahydropyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}- ... 2-chloro-3-methylbenzonitrile …
Matched Iupac: … 4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)-hexahydropyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}- ... 2-chloro-3-methylbenzonitrile …
3-(INDOL-3-YL) LACTATE
Experimental
Matched Name: … 3-(INDOL-3-YL) LACTATE …
Matched Iupac: … (2S)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2S)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid …
(2E)-3-(2,4-DICHLOROPHENYL)-N-HYDROXYACRYLAMIDE
Experimental
Matched Name: … (2E)-3-(2,4-DICHLOROPHENYL)-N-HYDROXYACRYLAMIDE …
Matched Iupac: … (2E)-3-(2,4-dichlorophenyl)-N-hydroxyprop-2-enamide …
Matched Iupac: … (2E)-3-(2,4-dichlorophenyl)-N-hydroxyprop-2-enamide …
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid …
S-3304
S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non Small Cell Lung Cancer, among others.
Investigational
Matched Iupac: … (2R)-3-(1H-indol-3-yl)-2-{5-[2-(4-methylphenyl)ethynyl]thiophene-2-sulfonamido}propanoic acid …
QR-313
QR-313 is an antisense oligonucleotide targeting exon 73. It is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Displaying drugs 6326 - 6350 of 9924 in total