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Displaying drugs 6376 - 6400 of 10204 in total

MK-3207

Mk3207 has been used in trials studying the treatment of Migraine and Migraine Disorders.
Investigational
Matched Iupac: … 2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxo-1,1',2',3-tetrahydrospiro ... [indene-2,3'-pyrrolo[2,3-b]pyridine]-6-yl]acetamide …

Velafermin

Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational

Plamotamab

Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)).
Investigational
Matched Description: … Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined …

N-[(2S)-4-Methyl-1-oxo-1-{[(4S)-3-oxo-1-(2-pyridinylsulfonyl)-4-azepanyl]amino}-2-pentanyl]-1-benzofuran-2-carboxamide

Experimental
Matched Name: … N-[(2S)-4-Methyl-1-oxo-1-{[(4S)-3-oxo-1-(2-pyridinylsulfonyl)-4-azepanyl]amino}-2-pentanyl]-1-benzofuran ... -2-carboxamide …
Matched Iupac: … (2S)-2-[(1-benzofuran-2-yl)formamido]-4-methyl-N-[(4S)-3-oxo-1-(pyridine-2-sulfonyl)azepan-4-yl]pentanamide …

Talampanel

Talampanel is a substance that is being studied in the treatment of brain tumors and other brain disorders, such as epilepsy and Parkinson disease. It is a type of AMPA receptor antagonist.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Icariin

Icariin has been investigated for the basic science of the Pharmacokinetic Profile of Icariin in Humans.
Investigational
Matched Iupac: … 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl ... )oxan-2-yl]oxy}-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE

Experimental
Matched Name: … GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE …
Matched Iupac: … 3,4-d][1,3]dioxol-2-yl]phosphonic acid ... [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …

gp209-2M antigen

The gp209-2M antigen is derived from gp209, and has potential immunomodulatory and antineoplastic activities.
Investigational

Ifinatamab deruxtecan

Investigational
Matched Synonyms: … -CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOH ... IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA …

AdimrSC-2f

The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia . A phase I study (NCT04522089) will investigate the safety and immunogenicity of the vaccine[L30553, L30548].
Investigational
Matched Description: … The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine …

SP4160

Experimental
Matched Iupac: … (2R)-2-[(diaminomethylidene)amino]-N-{2-[4-(3-{2,3-dichloro-4-[(4-acetamidophenyl)methoxy]phenyl}-1-methyl ... -1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoethyl}-4-methylpentanamide …

Melanoma antigen recognized by T-cells 1

Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery).
Investigational

NT-102

Investigational
Matched Synonyms: … 2-[(3-Methylbutyl)amino]-1,4-naphthalenedione …
Matched Iupac: … 2-[(3-methylbutyl)amino]-1,4-dihydronaphthalene-1,4-dione …

Suplatast

Suplatast is under investigation in clinical trial NCT05983471 (Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)).
Investigational
Matched Synonyms: … Sulfonium, (3-((4-(3-ethoxy-2-hydroxypropoxy)phenyl)amino)-3-oxopropyl)dimethyl- …
Matched Salts cas: … 94055-76-2 …

ATX-914

Axt914 is under investigation in clinical trial NCT00417261 (Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy Subjects.).
Investigational
Matched Iupac: … -2-one ... 1-[(2-bromoquinoxalin-6-yl)methyl]-6-(prop-2-yn-1-yloxy)-4-[4-(propan-2-yl)phenyl]-1,2-dihydroquinazolin …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid

Experimental
Matched Name: … 4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …

9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine

Experimental

HGS-TR2J

HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies. It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial.
Investigational
Matched Description: … HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced …

7-Aza-L-tryptophan

Experimental
Matched Iupac: … (2S)-2-amino-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid …

Indobufen

Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
Investigational
Matched Iupac: … 2-[4-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]butanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 2-Ring …

Metisazone

Experimental
Matched Iupac: … {[(3Z)-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino}thiourea …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester

Experimental
Matched Name: … Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester …
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2R)-2-hydroxy-2-phenylacetate …

4-[[(2S)-1-[[6-[(1-Amino-1-oxo-3-sulfanylpropan-2-yl)amino]-6-oxohexyl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[[2-[4-[difluoro(phosphono)methyl]phenyl]acetyl]amino]-4-oxobutanoic acid

Experimental
Matched Name: … 4-[[(2S)-1-[[6-[(1-Amino-1-oxo-3-sulfanylpropan-2-yl)amino]-6-oxohexyl]amino]-3-[4-[difluoro(phosphono ... )methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[[2-[4-[difluoro(phosphono)methyl]phenyl]acetyl]amino]-4-oxobutanoic …
Matched Iupac: … 3-{[(1S)-1-({5-[(1-carbamoyl-2-sulfanylethyl)carbamoyl]pentyl}carbamoyl)-2-{4-[difluoro(phosphono)methyl ... ]phenyl}ethyl]carbamoyl}-3-(2-{4-[difluoro(phosphono)methyl]phenyl}acetamido)propanoic acid …

2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID

Experimental
Matched Name: … 2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID …
Matched Iupac: … (2R,3S)-2,3-bis({[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy})pentanedioic acid …

(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE

Experimental
Matched Name: … (3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE …
Matched Iupac: … (3R,4S)-1-(3,4-dimethoxyphenyl)-3-(3-methylphenyl)piperidin-4-amine …
Displaying drugs 6376 - 6400 of 10204 in total