Displaying drugs 6626 - 6650 of 11152 in total
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-beta 1/3 inhibitor avid200 …
9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE
Experimental
Matched Name: … 9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE …
Matched Iupac: … 9-cyclopentyl-6-({2-[3-(1H-imidazol-1-yl)propoxy]phenyl}amino)-9H-purine-2-carbonitrile …
Matched Iupac: … 9-cyclopentyl-6-({2-[3-(1H-imidazol-1-yl)propoxy]phenyl}amino)-9H-purine-2-carbonitrile …
2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
TBD has been used in trials studying the treatment of Adenocarcinoma.
Investigational
Matched Name: … 2,2-bis(4-hydroxy-3-tert-butylphenyl)propane …
Matched Iupac: … 2-tert-butyl-4-[2-(3-tert-butyl-4-hydroxyphenyl)propan-2-yl]phenol …
Matched Iupac: … 2-tert-butyl-4-[2-(3-tert-butyl-4-hydroxyphenyl)propan-2-yl]phenol …
4-Bromo-2,5-dimethoxyamphetamine
Experimental
Illicit
Matched Iupac: … 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine …
Diphthamide
Experimental
Matched Synonyms: … 2-(3-Carboxyamido-3-(Trimethylammonio)Propyl)Histidine …
Matched Iupac: … [(1S)-3-{4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl}-1-carbamoylpropyl]trimethylazanium …
Matched Iupac: … [(1S)-3-{4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl}-1-carbamoylpropyl]trimethylazanium …
4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL
Experimental
Matched Name: … 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL …
Matched Iupac: … 4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …
Matched Iupac: … 4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …
Carbovir
Investigational
Matched Synonyms: … 6h-purin-6-one, 2-amino-1,9-dihydro-9-((1r,4s)-4-(hydroxymethyl)-2-cyclopenten-1-yl)-, rel- …
Matched Iupac: … 2-amino-9-[(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-6,9-dihydro-1H-purin-6-one …
Matched Iupac: … 2-amino-9-[(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-6,9-dihydro-1H-purin-6-one …
4-O-Demethylpenclomedine
Investigational
Matched Iupac: … 3,5-dichloro-2-methoxy-6-(trichloromethyl)-1,4-dihydropyridin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
2,3,-Dihydroxybenzoylserine
Experimental
Matched Iupac: … (2S)-2-[(2,3-dihydroxyphenyl)formamido]-3-hydroxypropanoic acid …
(6-METHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL)METHYLPHOSPHINATE
Experimental
Matched Name: … (6-METHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL)METHYLPHOSPHINATE …
Matched Iupac: … {[(2S)-6-methyl-3,4-dihydro-2H-1-benzopyran-2-yl]methyl}phosphinate …
Matched Iupac: … {[(2S)-6-methyl-3,4-dihydro-2H-1-benzopyran-2-yl]methyl}phosphinate …
Cinalukast
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Experimental
Matched Synonyms: … 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Proquazone
Experimental
Matched Iupac: … 7-methyl-4-phenyl-1-(propan-2-yl)-1,2-dihydroquinazolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
RP-L201
Investigational
Matched Synonyms: … Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene …
3-deoxy-D-lyxo-hexonic acid
Experimental
Matched Synonyms: … D-2-keto-3-deoxygalactonate …
Matched Name: … 3-deoxy-D-lyxo-hexonic acid …
Matched Name: … 3-deoxy-D-lyxo-hexonic acid …
Phosphoaminophosphonic Acid-Adenylate Ester
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]
Experimental
Matched Iupac: … ({[({[(2S,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Description: … 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. …
Matched Description: … 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. …
2,5-Dimethoxy-4-ethylamphetamine
Experimental
Illicit
Matched Iupac: … 1-(4-ethyl-2,5-dimethoxyphenyl)propan-2-amine …
Aptazapine
Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity. It antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine. Although Aptazapine reached clinical trials, it...
Experimental
Matched Description: … antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5- …
Matched Salts cas: … 71576-41-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 71576-41-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Diethylene glycol ethyl methyl ether
Experimental
Matched Synonyms: … 1-ethoxy-2-(2-methoxyethoxy)ethane …
Matched Iupac: … 1-ethoxy-2-(2-methoxyethoxy)ethane …
Matched Iupac: … 1-ethoxy-2-(2-methoxyethoxy)ethane …
1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine
Experimental
Matched Name: … 1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine …
Matched Iupac: … N''-[4-(2-oxo-2-phenylethyl)phenyl]guanidine …
Matched Iupac: … N''-[4-(2-oxo-2-phenylethyl)phenyl]guanidine …
Oridonin
Oridonin is under investigation in clinical trial NCT05130892 (Effect of Inflammasome Inhibitor on Hscrp in Patients After PCI).
Investigational
Matched Synonyms: … .,20-epoxy-1.alpha.,6.beta.,7,14-tetrahydroxy-, (14r)- ... Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1.alpha.,6.beta.,7.alpha.,14r)- …
Reproxalap
Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis, and Sjögren-Larsson syndrome. NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.
Investigational
Matched Synonyms: … NS-2 …
Matched Iupac: … 2-(3-amino-6-chloroquinolin-2-yl)propan-2-ol …
Matched Description: … Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics ... [L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-(3-amino-6-chloroquinolin-2-yl)propan-2-ol …
Matched Description: … Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics ... [L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
AGS-499
Investigational
Displaying drugs 6626 - 6650 of 11152 in total