Displaying drugs 651 - 675 of 2703 in total
Nisevokitug
Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … Anti-tgf-beta monoclonal antibody nis793 …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gentulizumab
Investigational
Matched Synonyms: … GENTULIZUMAB (anti-CD47 Humanized Monoclonal Antibody) …
Arsanilic acid
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
Experimental
Vet approved
Matched Synonyms: … atoxylic acid ... Arsanilic acid ... 4-arsanilic acid …
Matched Name: … Arsanilic acid …
Matched Iupac: … (4-aminophenyl)arsonic acid …
Matched Description: … It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] ... An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
Matched Name: … Arsanilic acid …
Matched Iupac: … (4-aminophenyl)arsonic acid …
Matched Description: … It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] ... An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
Maleic acid
Experimental
Matched Synonyms: … Maleic acid ... Toxilic acid ... (Z)-butenedioic acid …
Matched Name: … Maleic acid …
Matched Iupac: … (2Z)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Acid Etching, Dental ... Dicarboxylic Acids …
Matched Name: … Maleic acid …
Matched Iupac: … (2Z)-but-2-enedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Acid Etching, Dental ... Dicarboxylic Acids …
Labetuzumab
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Synonyms: … Monoclonal antibody hMN-14 ... MN14 monoclonal antibody to carcinoembryonic antigen …
Matched Description: … Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth …
Matched Categories: … Amino Acids, Peptides, and Proteins …
(2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid
Experimental
Matched Name: … (2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid …
Matched Iupac: … (2R)-2-benzyl-4,4-dihydroxy-5-nitropentanoic acid …
Matched Iupac: … (2R)-2-benzyl-4,4-dihydroxy-5-nitropentanoic acid …
norUrsodeoxycholic acid
norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC).
Investigational
Matched Synonyms: … Norucholic acid ... Nor-ursodeoxycholic acid ... 24-norursodeoxycholic acid …
Matched Name: … norUrsodeoxycholic acid …
Matched Iupac: … 9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]butanoic acid …
Matched Description: … norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid …
Matched Categories: … Bile Acids and Salts ... Cholic Acids …
Matched Name: … norUrsodeoxycholic acid …
Matched Iupac: … 9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]butanoic acid …
Matched Description: … norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid …
Matched Categories: … Bile Acids and Salts ... Cholic Acids …
Gondoic acid
Experimental
Matched Synonyms: … Eicosenoic acid ... (11Z)-Eicosenoic acid ... (11Z)-Icosenoic acid …
Matched Name: … Gondoic acid …
Matched Iupac: … (11Z)-icos-11-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Matched Name: … Gondoic acid …
Matched Iupac: … (11Z)-icos-11-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Nitrazepam
A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Matched Synonyms: … 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one ... 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one ... 7-nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … A benzodiazepine derivative used as an anticonvulsant and hypnotic. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … A benzodiazepine derivative used as an anticonvulsant and hypnotic. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Palmitoleic Acid
Experimental
Matched Synonyms: … zoomaric acid ... (9Z)-hexadecenoic acid ... (Z)-9-hexadecenoic acid …
Matched Name: … Palmitoleic Acid …
Matched Iupac: … (9Z)-hexadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Matched Name: … Palmitoleic Acid …
Matched Iupac: … (9Z)-hexadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
meso-Tartaric acid
Experimental
Matched Synonyms: … Erythraric acid ... i-Tartaric acid ... m-tartaric acid …
Matched Name: … meso-Tartaric acid …
Matched Iupac: … (2R,3S)-2,3-dihydroxybutanedioic acid …
Matched Name: … meso-Tartaric acid …
Matched Iupac: … (2R,3S)-2,3-dihydroxybutanedioic acid …
2-Naphthalenesulfonic acid
Experimental
Matched Synonyms: … β-naphthylsulfonic acid ... beta-Naphthylsulfonic acid ... beta-Naphthalenesulfonic acid …
Matched Name: … 2-Naphthalenesulfonic acid …
Matched Iupac: … naphthalene-2-sulfonic acid …
Matched Categories: … Sulfur Acids ... Arylsulfonic Acids ... Sulfonic Acids …
Matched Name: … 2-Naphthalenesulfonic acid …
Matched Iupac: … naphthalene-2-sulfonic acid …
Matched Categories: … Sulfur Acids ... Arylsulfonic Acids ... Sulfonic Acids …
Phenylacetic acid
Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries...
Approved
Matched Synonyms: … -TOLUIC ACID ... α-toluic acid ... -PHENYLACETIC ACID …
Matched Name: … Phenylacetic acid …
Matched Iupac: … 2-phenylacetic acid …
Matched Description: … Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional ... manufacture of substituted amphetamines), it is subject to controls in countries including the United States and …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... sodium benzoate and sodium phenylacetate ... Various Alimentary Tract and Metabolism Products …
Matched Name: … Phenylacetic acid …
Matched Iupac: … 2-phenylacetic acid …
Matched Description: … Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional ... manufacture of substituted amphetamines), it is subject to controls in countries including the United States and …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... sodium benzoate and sodium phenylacetate ... Various Alimentary Tract and Metabolism Products …
Hydracrylic acid
Experimental
Matched Synonyms: … 3-Hydroxypropanoic acid ... 3-Hydroxypropionic acid ... β-hydroxypropionic acid …
Matched Name: … Hydracrylic acid …
Matched Iupac: … 3-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Hydracrylic acid …
Matched Iupac: … 3-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Flutamide
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Matched Synonyms: … 4'-nitro-3'-trifluoromethylisobutyranilide ... α,α,α-trifluoro-2-methyl-4'-nitro-m-propionotoluidide …
Matched Iupac: … 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Description: … An antiandrogen with about the same potency as cyproterone in rodent and canine species. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Matched Description: … An antiandrogen with about the same potency as cyproterone in rodent and canine species. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
MK-4721
MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and bladder cancers.
Investigational
Matched Synonyms: … ANTI-PSCA MONOCLONAL ANTIBODY AGS-1C4D4 …
Matched Description: … significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and ... MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and ... MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lucatumumab
Investigational
Matched Synonyms: … Recombinant anti-CD40 monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ruplizumab
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody 5c8 …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
MEDI-6469
MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies).
Investigational
Matched Synonyms: … Agonistic anti-OX40 monoclonal antibody MEDI6469 …
Matched Description: … and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies) ... MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety …
Matched Description: … and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies) ... MEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety …
Ivuxolimab
Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational
Matched Synonyms: … Anti-OX40 Antibody PF-04518600 …
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Synonyms: … Anti-CD20/CD3 monoclonal antibody REGN1979 …
Matched Description: … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, ... Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody ... to the development of neurologic toxicity; however, it can lead to the development of cytokine release …
Matched Description: … [A254187] In December 2020, the FDA placed a partial clinical hold and requested the drug developer, ... Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody ... to the development of neurologic toxicity; however, it can lead to the development of cytokine release …
ATI-1013
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
HLX-58
HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.
Investigational
Matched Synonyms: … Recombinant anti-claudin 18.2 monoclonal antibody …
Matched Description: … HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2. …
Matched Description: … HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2. …
Fianlimab
Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma).
Investigational
Matched Synonyms: … Anti-lag-3 monoclonal antibody regn3767 …
Matched Description: … Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab ... Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma …
Matched Description: … Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab ... Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma …
Displaying drugs 651 - 675 of 2703 in total