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Displaying drugs 6751 - 6775 of 7615 in total
Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
Investigational
Matched Synonyms: … 4-(2-(cyclopropylmethoxy)-5-methylsulfonylphenyl)-2-methylisoquinolin-1-one ... 1(2h)-isoquinolinone, 4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl)-2-methyl- …
Investigational
Matched Synonyms: … 2-butenedioic acid (2e)-, 1-(2-(diethylamino)-2-oxoethyl) 4-methyl ester …
Experimental
Matched Synonyms: … (2-sulfanyl-3-phenylpropanoyl)-phe-tyr …
Matched Name: … N-[(2S)-3-Phenyl-2-sulfanylpropanoyl]-L-phenylalanyl-L-tyrosine …
Matched Iupac: … (2S)-3-(4-hydroxyphenyl)-2-[(2S)-3-phenyl-2-[(2S)-3-phenyl-2-sulfanylpropanamido]propanamido]propanoic …
Experimental
Matched Iupac: … {1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2 ... -yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1lambda5 ... -pyridin-1-ylium-3-carboximidoyl}sulfanide …
Experimental
Matched Iupac: … yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan ... -3-yl]oxy}phosphonic acid ... {[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1- …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-[8-(dimethylamino …
Experimental
Matched Iupac: … {[(2R,3R,4R,5R)-2-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy ... }({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic …
Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).
Investigational
Matched Iupac: … 10-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino ... )-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl]-4,4-dimethyl-1,10-diazatricyclo[6.4.0.0^{2,6}]dodeca-2(6) …
Experimental
Matched Name: … 2-phenyl-1H-imidazole-4-carboxylic acid …
Matched Iupac: … 2-phenyl-1H-imidazole-4-carboxylic acid …
Experimental
Matched Name: … (2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE …
Matched Iupac: … (2R)-2-(4-chlorophenyl)-2-phenylethan-1-amine …
Experimental
Matched Name: … 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE …
Matched Iupac: … 1-[4-methyl-2-(phenylamino)-1,3-thiazol-5-yl]ethan-1-one …
Experimental
Matched Name: … 2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol …
Matched Iupac: … 2-[(3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propyl)amino]-2-(hydroxymethyl)propane-1,3-diol …
Experimental
Matched Name: … 6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide …
Matched Iupac: … 6-chloro-N-(pyrimidin-5-yl)-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzoxazole-7-carboxamide …
Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research to select genetically engineered cells. Resistance to Geneticin is...
Experimental
Matched Iupac: … (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4- ... (methylamino)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol …
Matched Description: … , APH 3‘ II. ... Resistance to Geneticin is conferred by the neo gene from Tn5 encoding an aminoglycoside 3‘-phosphotransferase …
Experimental
Matched Iupac: … ,4R,5R)-2-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy})phosphinic ... {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R,3R …
Troxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
Investigational
Matched Iupac: … 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy ... -6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-positive, Her2-negative Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Iupac: … 12'-({5-[4-(propan-2-yl)piperazin-1-yl]pyridin-2-yl}amino)-2',5',11',13'-tetraazaspiro[cyclohexane-1,3 …
Matched Description: … Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination …
Investigational
Experimental
Matched Name: … 3-Fluoro-2-(Phosphonooxy)Propanoic Acid …
Matched Iupac: … (2R)-3-fluoro-2-(phosphonooxy)propanoic acid …
Experimental
Matched Name: … N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE …
Matched Iupac: … 3-oxo-N-[(3S)-2-oxooxolan-3-yl]dodecanamide …
Experimental
Matched Name: … 13-cis-12-(3'-Carboxyphenyl)retinoic acid …
Matched Iupac: … 3-[(1Z,5E,7E)-1-carboxy-2,6-dimethyl-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-1,3,5,7-tetraen-3-yl]benzoic …
Experimental
Matched Name: … N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide …
Matched Iupac: … 2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl …
Displaying drugs 6751 - 6775 of 7615 in total