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Displaying drugs 7151 - 7175 of 7792 in total
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Experimental
Matched Iupac: … yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... 5R,6S)-6-{[(2R,3R,4R,5S)-4,5-dihydroxy-6-(hydroxyamino)-2-(hydroxymethyl)-2,3,4,5-tetrahydropyridin-3- …
Experimental
Matched Name: … 4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(2R,3S,5R)-5-hydroxy-2-pentyloxolan-3-yl]sulfanyl …
Experimental
Matched Iupac: … magnesium(2+) (3R,21S,22S)-16-ethenyl-11-ethyl-3-(methoxycarbonyl)-12,17,21,26-tetramethyl-4-oxo-22-( ... [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1,5,8(26),9,11,13(25),14,16,18,20(23)-decaene-7,24 ... 3-oxo-3-{[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Experimental
Matched Name: … N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE …
Matched Iupac: … N-(2-methoxyethyl)-4-({4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)benzene-1-sulfonamide …
Experimental
Matched Iupac: … 6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Experimental
Matched Synonyms: … 3-phenyl-1H-naphtho(2,1-b)pyran-1-one …
Matched Iupac: … 3-phenyl-1H-benzo[f]chromen-1-one …
Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Investigational
Experimental
Matched Name: … Di-Stearoyl-3-Sn-Phosphatidylethanolamine …
Experimental
Matched Iupac: … (2R,3R)-2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]-3-hydroxybutanoic acid …
Experimental
Matched Name: … 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid …
Matched Iupac: … 3-{5-[(1Z)-2-nitropent-1-en-1-yl]furan-2-yl}benzoic acid …
Investigational
Matched Name: … Glyceraldehyde-3-Phosphate Dehydrogenase …
Matched Categories: … Glyceraldehyde-3-Phosphate Dehydrogenases, antagonists & inhibitors …
Experimental
Matched Name: … S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea …
Matched Iupac: … (E)-N'-[4-(trifluoromethyl)phenyl](ethylsulfanyl)methanimidamide …
Experimental
Matched Name: … ethyl 2-amino-4-hydroxypyrimidine-5-carboxylate …
Matched Iupac: … ethyl 2-amino-4-hydroxypyrimidine-5-carboxylate …
Experimental
Matched Name: … D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-4-methylpentanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide …
Experimental
Matched Name: … N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide …
Matched Iupac: … 2-{[1,1'-biphenyl]-4-sulfonamido}-N-oxoacetamide …
Experimental
Matched Name: … 4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID …
Matched Iupac: … 4-[(cyclohexylcarbamoyl)amino]butanoic acid …
Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).
Investigational
Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia).
Investigational
Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from dogs and cats.
Experimental
Vet approved
Matched Synonyms: … 2,2'-Methylenebis(4-chlorophenol) …
Matched Iupac: … 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol …
Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Experimental
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one ... 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Displaying drugs 7151 - 7175 of 7792 in total