Displaying drugs 701 - 725 of 1060 in total
HH-009
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Ezabenlimab
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 ... .gamma.4-chain), disulfide with human monoclonal bi754091 .kappa. …
Zimberelimab
Investigational
Matched Synonyms: … Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 ... .gamma.4-chain), disulfide with human monoclonal ab122 .lambda. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Domvanalimab
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus ... musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappa …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
Matched Description: … Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination …
Levodopa
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Synonyms: … 3-Hydroxy-L-tyrosine …
Matched Description: … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally ... Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Dopa and Dopa Derivatives ... levodopa and decarboxylase inhibitor ... levodopa, decarboxylase inhibitor and COMT inhibitor …
Matched Description: … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally ... Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous ... The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Dopa and Dopa Derivatives ... levodopa and decarboxylase inhibitor ... levodopa, decarboxylase inhibitor and COMT inhibitor …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Matched Description: … Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Human Menstrual Blood-derived Stem Cells
Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner cell mass of blastocysts while ASCs are deposited into adult tissues with restricted...
Investigational
Matched Name: … Human Menstrual Blood-derived Stem Cells …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Matched Description: … embryonic stem cells (ESCs) and adult stem cells (ASC). ... Stem cells are self-renewing and proliferate without differentiation, with the two major groups being ... These cells possess a high rate of proliferation and multi-lineage differentiation potency. …
Human Recombinant Bone Morphogenetic Protein 4
Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Human Embryonic Stem Cell-derived Astrocytes
Investigational
Matched Name: … Human Embryonic Stem Cell-derived Astrocytes …
Recombinant human palmitoyl protein thioesterase-1
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
Saruplase
Experimental
Matched Synonyms: … KINASE (ENZYME-ACTIVATING), PROURO- (HUMAN CLONE PUK33 REDUCED) ... PROUROKINASE (ENZYME ACTIVATING) (HUMAN CLONE PUK4/PUK18), NONGLYCOSYLATED ... PLASMINOGEN ACTIVATOR, PRO- (HUMAN LIVER UROKINASE-TYPE PROTEIN MOIETY REDUCED) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
BQ-788
Investigational
Matched Synonyms: … D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media
Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic. The condition medium (CM) derived from these MSCs has also been implicated...
Investigational
Matched Synonyms: … Allogeneic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media ... Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … Human somatomedin C ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues …
Gresonitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Vepsitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Pegzilarginase
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Investigational
Matched Synonyms: … Optimised human arginase I ... Co-ArgI-PEG modified human arginase I …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Fecal microbiota
Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Synonyms: … Donor human stool ... Donor human stool spores (ethanol treated) …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Thrombomodulin Alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Adenovirus type 7 vaccine live
Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Recombinant human highly phosphorylated acid alpha-glucosidase
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Matched Name: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Matched Name: … Recombinant human highly phosphorylated acid alpha-glucosidase …
Human adenovirus e serotype 4 strain cl-68578 antigen
Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.
Approved
Matched Synonyms: … Human Adenovirus Serotype 4 Strain Cl-68578 ... Human Adenovirus E Serotype 4 Strain Cl-68578 ... Human Adenovirus Serotype 4 Vaccine Strain Cl-68578 …
Matched Name: … Human adenovirus e serotype 4 strain cl-68578 antigen …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 4 Vaccine …
Matched Name: … Human adenovirus e serotype 4 strain cl-68578 antigen …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 4 Vaccine …
2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE
Experimental
Matched Name: … 2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE …
DR-01
DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Synonyms: … Human anti-CD94 IgG1 monoclonal antibody (non-fucosylated) …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Nirsevimab
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human ... Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897 ... monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4*01 ( …
Matched Description: … neutralizes several RSV A and B strains. ... Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Description: … neutralizes several RSV A and B strains. ... Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Displaying drugs 701 - 725 of 1060 in total