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Displaying drugs 701 - 725 of 909 in total
AVR-RD-04 is an investigational gene therapy for cystinosis. It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.
Investigational
Matched Synonyms: … autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized …
Matched Description: … It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting …
Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN VIMENTIN) (HUMAN-MUS MUSCULUS .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS …
Matched Description: … Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and ... Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)). …
Vilamakitug is under investigation in clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human Antibody Versus Trifluridine/tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine).
Investigational
Matched Synonyms: … (human monoclonal xb2001 .gamma.4-chain), disulfide with human monoclonal xb2001 .kappa. …
Matched Description: … NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human Antibody Versus
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(SERUM AMYLOID P PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL GSK2398852 HEAVY CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 27) (human monoclonal SRF388 γ1-chain), disulfide with human ... immunoglobulin G1-kappa, anti-[IL27 (interleukin 27,IL27p28, IL27A)], Homo sapiens monoclonal antibody,gamma1 heavy
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … Immunoglobulin g 1 (human monoclonal pe1-1 anti-hepatitis b virus surface antigen), disulfide with human ... Immunoglobulin g 1 (human monoclonal pe1-1 anti-hepatitis b virus surface antigen), disulfide with human ... Immunoglobulin g1, anti-(hepatitis b virus surface antigen) (human monoclonal pe1-1 .gamma.1-chain), disulfide with
Investigational
Matched Synonyms: … anti-(human epidermal growth factor receptor her3) (human monoclonal isu104 .gamma.1-chain), disulfide with
Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Description: … ) and pharmaceuticals (including barbiturates). ... Each domain comprises two separate sub-domains (A and B) [A40060]. ... both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101]. …
Matched Mixtures name: … Venomil Honey Bee Venom (12mcg) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Sterile Diluent for Allergenic Extracts Normal Saline With Hsa ... Diluent for Allergenic Extract Sterile Albumin Saline With Phenol ... Sterile Diluent for Allergenic Extract - Albumin Saline With Phenol …
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia).
Investigational
Matched Synonyms: … .-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimer …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults ... With Warm Autoimmune Hemolytic Anemia). …
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
Matched Synonyms: … an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z …
Matched Description: … WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … VERAN-D ... VERAN D® CAPSULAS 20 MG ... VERAN D INYECTABLE 40 MG./ 2ML. …
Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched International brands: … Stemiz
Matched Description: … manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4(228-proline), anti-(human cd47 antigen) (human monoclonal tj011133 .gamma.4-chain), disulfide with
Matched Description: … and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without ... Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and ... Venetoclax in Participants With Myelodysplastic Syndrome). …
Xeligekimab is under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With Uncontrolled Seasonal Allergic Rhinitis.).
Investigational
Matched Synonyms: … g4 (235-proline), anti-(human interleukin 17a) (human monoclonal gr1501 .gamma.4-chain), disulfide with
Matched Description: … under investigation in clinical trial NCT06028490 (A Study of Il4rα Monoclonal Antibody in Patients With
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN-MUS MUSCULUS MONOCLONAL TST001 .GAMMA.1-CHAIN), DISULFIDE WITH
Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).
Investigational
Matched Synonyms: … human vascular endothelial growth factor receptor 2) (human monoclonal ak109 .gamma.1-chain), disulfide with
Matched Description: … Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) ... Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein …
Matched Description: … [L10866] In 2014, Merck Inc. signed a licensing agreement with NewLink for further development and marketing ... the World Health Organization (WHO) lifted the Public Health Emergency of International Concern (PHEIC ... [A188997] Confirmed outbreaks of Ebola virus disease have been documented since the 1970s, mostly …
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … with morphine and are of shorter duration. ... that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Categories: … pethidine and antispasmodics ... pethidine, combinations with psycholeptics …
Matched Products: … Demerol 50 mg/ml (multiple Dose With Metacresol As Preservative) …
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain), disulfide with
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and ... was finally approved in December 2022 for the treatment of flares in adult patients with generalized …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Black cohosh (Actaea racemosa or Cimicifuga racemosa), a member of the buttercup family, is a perennial plant which native to North America. Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. Black cohosh has a long history of use. Native Americans used it for its...
Experimental
Matched Synonyms: … Cimicifuga racemosa root with rhizome …
Matched Description: … [L2301] Black cohosh has been associated with serious safety concerns. ... mood disturbance, and hot flushes. ... Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism …
Matched Categories: … Herbs and Natural Products ... Genito Urinary System and Sex Hormones …
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Synonyms: … anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) fusion protein with ... peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor 5) (human-Lama glama …
Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Synonyms: … HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10 ... INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and ... Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia). …
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … human respiratory syncytial virus fusion glycoprotein f0 (protein f))human monoclonal antibody.gamma.1 heavy ... human respiratory syncytial virus fusion protein)(human monoclonal med18897 .gamma.1-chain), disulfide with
Matched Description: … [L44146] Nirsevimab was also approved by Health Canada on April 19, 2023 and by the FDA in July 17, 2023 ... of the viral entry process, and neutralizes several RSV A and B strains. ... antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Displaying drugs 701 - 725 of 909 in total