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Displaying drugs 7376 - 7400 of 10582 in total

Posizolid

Posizolid (AZD2563) is an oxazolidinone antibiotic. In July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were no longer pursuing the development of Posizolid, presumably due to negative trial results (though no results were reported).
Investigational
Matched Iupac: … (5R)-3-(4-{1-[(2S)-2,3-dihydroxypropanoyl]-1,2,3,6-tetrahydropyridin-4-yl}-3,5-difluorophenyl)-5-[(1,2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Trigonellamide

Trigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers).
Investigational
Matched Iupac: … 3-carbamoyl-1-methylpyridin-1-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bafetinib

Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Iupac: … N-[3-({[4,5'-bipyrimidin]-2-yl}amino)-4-methylphenyl]-4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

LY-2608204

LY2608204 has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … (1R,2S)-2-cyclohexyl-1-[4-(cyclopropanesulfonyl)phenyl]-N-(5-{[2-(pyrrolidin-1-yl)ethyl]sulfanyl}-1,3 ... -thiazol-2-yl)cyclopropane-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Verubecestat

Verubecestat is under investigation for the treatment of Alzheimer's Disease, Prodromal Alzheimer's disease, and Amnestic Mild Cognitive Impairment. Verubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1 or β secretase) inhibitor. In July 2013, Merck announced positive results for Phase Ib trials of Verubecestat. In the study,...
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Apricoxib

Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.
Investigational
Matched Iupac: … 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Rimazolium

Rimazolium is an experimental analgesic drug .
Experimental
Matched Iupac: … 3-(ethoxycarbonyl)-1,6-dimethyl-4-oxo-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-1-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Osoresnontrine

Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks in Patients With Schizophrenia on Stable Antipsychotic Treatment.).
Investigational
Matched Iupac: … 1-(oxan-4-yl)-6-[(pyridin-2-yl)methyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Altiratinib

Investigational
Matched Iupac: … N1-{4-[(2-cyclopropaneamidopyridin-4-yl)oxy]-2,5-difluorophenyl}-N'1-(4-fluorophenyl)cyclopropane-1,1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Manitimus

FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CP-547632

CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.
Investigational
Matched Iupac: … 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(pyrrolidin-1-yl)butyl]carbamoyl}amino)-1,2-thiazole-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-04620110

PF-04620110 is under investigation in clinical trial NCT01146327 (A Multiple Dose Study Of PF-04620110 In Healthy Overweight Or Obese Subjects).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone

Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial NCT02688101 (Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced Solid Tumors).
Investigational
Matched Iupac: … 1-{[bis(pyridin-2-yl)methylidene]amino}-3-cyclohexyl-3-methylthiourea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Florasulam

Florasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Zinc orotate

Experimental
Matched Salts cas: … 270083-97-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Proxalutamide

Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide (GT0918) in Subjects With Metastatic Castrate Resistant Prostate Cancer).
Investigational
Matched Iupac: … 4-(4,4-dimethyl-3-{6-[3-(1,3-oxazol-2-yl)propyl]pyridin-3-yl}-5-oxo-2-sulfanylideneimidazolidin-1-yl) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE

Experimental
Matched Iupac: … (1R,3R,5S)-8,8-dimethyl-3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yloxy}-8-azabicyclo …

DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE

Experimental

(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)

Experimental

2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol

Experimental

Testosterone succinate

Experimental
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …

(1S,2R,3S,4R,5R)-2,3,4-trihydroxy-N-octyl-6-oxa-8-azabicyclo[3.2.1]octane-8-carbothioamide

(1S,2R,3S,4R,5R)-2,3,4-trihydroxy-N-octyl-6-oxa-8-azabicyclo[3.2.1]octane-8-carbothioamide is a solid. This compound belongs to the oxepanes. These are compounds containing an oxepane ring, which is an a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms. This drug targets the protein beta-glucosidase A.
Experimental

Arylomycin A2

Experimental
Matched Iupac: … propanamido]-N-methylacetamido}-3,18-dihydroxy-11-methyl-10,13-dioxo-9,12-diazatricyclo[13.3.1.1^{2,6}]icosa-1( …

2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide

Experimental
Displaying drugs 7376 - 7400 of 10582 in total