Zinc orotate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Zinc orotate is a zinc supplement indicated in zinc deficiency.

Generic Name
Zinc orotate
DrugBank Accession Number
DB15720
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 375.56
Monoisotopic: 373.947705
Chemical Formula
C10H6N4O8Zn
Synonyms
  • Orotate zinc
  • Zinc diorotate
  • Zinc orotate

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Zinc orotate dihydrate2R18GO895S270083-97-1KAXHRUFHOVCLAS-UHFFFAOYSA-L

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Z722242H10
CAS number
60388-02-5
InChI Key
YNMDOZLVAPMCBD-UHFFFAOYSA-L
InChI
InChI=1S/2C5H4N2O4.Zn/c2*8-3-1-2(4(9)10)6-5(11)7-3;/h2*1H,(H,9,10)(H2,6,7,8,11);/q;;+2/p-2
IUPAC Name
zinc(2+) bis(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate)
SMILES
[Zn++].[O-]C(=O)C1=CC(=O)NC(=O)N1.[O-]C(=O)C1=CC(=O)NC(=O)N1

References

General References
  1. BASG Product Information: Zinkorotat-Pos (zinc orotate) tablet [Link]
ChemSpider
97963
RxNav
11422

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet, film coatedOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.635 mg/mLALOGPS
logP0.14ALOGPS
logP-1.2ChemAxon
logS-2.8ALOGPS
pKa (Strongest Acidic)2.64ChemAxon
pKa (Strongest Basic)-6ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area98.33 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity44.11 m3·mol-1ChemAxon
Polarizability12.01 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on August 11, 2020 15:28 / Updated on May 14, 2021 01:07