This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Zinc orotate is a zinc supplement indicated in zinc deficiency.
- Generic Name
- Zinc orotate
- DrugBank Accession Number
- DB15720
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Zinc orotate (DB15720)
- Weight
- Average: 375.56
Monoisotopic: 373.947705 - Chemical Formula
- C10H6N4O8Zn
- Synonyms
- Orotate zinc
- Zinc diorotate
- Zinc orotate
Pharmacology
- Indication
Not Available
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Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Zinc deficiency ••• ••• •••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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Ingredient UNII CAS InChI Key Zinc orotate dihydrate 2R18GO895S 270083-97-1 KAXHRUFHOVCLAS-UHFFFAOYSA-L
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Z722242H10
- CAS number
- 60388-02-5
- InChI Key
- YNMDOZLVAPMCBD-UHFFFAOYSA-L
- InChI
- InChI=1S/2C5H4N2O4.Zn/c2*8-3-1-2(4(9)10)6-5(11)7-3;/h2*1H,(H,9,10)(H2,6,7,8,11);/q;;+2/p-2
- IUPAC Name
- zinc(2+) bis(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate)
- SMILES
- [Zn++].[O-]C(=O)C1=CC(=O)NC(=O)N1.[O-]C(=O)C1=CC(=O)NC(=O)N1
References
- General References
- BASG Product Information: Zinkorotat-Pos (zinc orotate) tablet [Link]
- External Links
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, film coated Oral 40 mg - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.635 mg/mL ALOGPS logP 0.14 ALOGPS logP -1.2 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 2.64 Chemaxon pKa (Strongest Basic) -6 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 98.33 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 44.11 m3·mol-1 Chemaxon Polarizability 12.01 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at August 11, 2020 15:28 / Updated at May 14, 2021 01:07