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Displaying drugs 7676 - 7700 of 12990 in total

MGN-4893

MGN-4893 is an inhibitor of microRNA-451. In February 2011, it was granted FDA orphan designation for the treatment of polycythemia vera.
Investigational

MEDI-491

MEDI-491 is a recombinant human parvovirus B19 vaccine composed of the VP1 and VP2 capsid proteins.
Investigational

INO-4913

Investigational

5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID

Experimental

Simmondsia chinensis seed

Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental

5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide

Experimental

(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid

Experimental
Matched Name: … (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid …
Matched Iupac: … (2S)-3-{4-[2-(9H-carbazol-9-yl)ethoxy]phenyl}-2-ethoxypropanoic acid …

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate

Experimental
Matched Name: … methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate …
Matched Iupac: … methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-oxopentanoate …

3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID

Experimental
Matched Name: … 3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-[(4-chlorophenyl)sulfamoyl]thiophene-2-carboxylic acid …

GP-100 antigen

GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma).
Investigational

Volrubigene ralaparvovec

Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational

8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide

Experimental
Matched Name: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole …
Matched Iupac: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1H,2H,3H,6H-pyrrolo[3,4-e]indole-7-carboxamide …

3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE

Experimental

Stavudine triphosphate

Experimental
Matched Iupac: … {[hydroxy({[hydroxy({[(2S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2,5-dihydrofuran …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Binodenoson

Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a...
Investigational
Matched Iupac: … (2R,3R,4S,5R)-2-{6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazin-1-yl]-9H-purin-9-yl}-5-(hydroxymethyl …

ABX1100

ABX1100 is an investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 (Gys1), an enzyme that is responsible for glycogen synthesis in the muscle. It was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.
Investigational
Matched Description: … investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 …

(S)-acetoin

A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.
Experimental
Matched Synonyms: … (S)-2-acetoin …
Matched Name: … (S)-acetoin …

Siroheme

Experimental
Matched Iupac: … (24)-nonaen-4-yl]propanoic acid ... )-9,15,19-tris(2-carboxyethyl)-5,10,14,20-tetrakis(carboxymethyl)-5,10-dimethyl-2,22,23,25-tetraaza-1- ... ferraoctacyclo[11.9.1.1^{1,8}.1^{3,21}.0^{2,6}.0^{16,23}.0^{18,22}.0^{11,25}]pentacosa-3,6,8,11,13,15,17,19,21 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …

SB-559448

SB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets. This drug is developed by GlaxoSmithKline and used to treat Thrombocytopenia.Thrombocytopenia (decreased platelet count) is a common side effect of many chemotherapies and can lead to uncontrolled...
Investigational

SKF-91488

Experimental
Matched Iupac: … [4-(carbamimidoylsulfanyl)butyl]dimethylamine …

Simendan

Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
Investigational
Matched Iupac: … 1-cyano-N-[4-(6-hydroxy-4-methyl-4,5-dihydropyridazin-3-yl)phenyl]methanecarbohydrazonoyl cyanide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Samarium

Samarium has been used in trials studying the treatment and prevention of Pain, Cancer, Metastasis, Prostate Cancer, and Metastatic Osteosarcoma, among others.
Investigational

SB-773812

SB-773812 is under investigation in clinical trial NCT00259870 (SB-773812 Administered in Adults With Schizophrenia).
Investigational
Matched Iupac: … 7-{4-[(4-chlorophenyl)methoxy]benzenesulfonyl}-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine …

SNS01-T

SNS01-T is a gene therapy nanoparticle. It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.
Investigational

Saposin C

Saposin C is a lysosomal protein. Recombinant, non-glycosylated Saposin C is an active ingredient of BXQ-350, which is a novel, investigational anti-neoplastic therapy. BXQ-350 consists of Saposin C and the phospholipid dioleoylphosphatidyl-serine (DOPS), a phospholipid located on cell membranes.
Investigational
Displaying drugs 7676 - 7700 of 12990 in total