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Displaying drugs 7676 - 7700 of 12984 in total

N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid

N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.
Experimental
Matched Name: … N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid …
Matched Iupac: … (2S)-2-amino-4-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)amino …
Matched Description: … N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. …

KOS-1584

KOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Investigational
Matched Iupac: … (4S,7R,8S,9S,10E,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(2-methyl-1,3-thiazol-4-yl) ... prop-1-en-2-yl]-1-oxacyclohexadeca-10,13-diene-2,6-dione …

KOSN-1724

KOSN-1724 is under investigation in clinical trial NCT01379287 (Dose-Escalation Safety and Pharmacokinetic Study of Iso-Fludelone in Patients With Advanced Solid Tumors).
Investigational
Matched Iupac: … (4S,7R,8S,9S,10Z,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(5-methyl-1,2-oxazol-3-yl)prop ... -1-en-2-yl]-1-oxacyclohexadeca-10,13-diene-2,6-dione …

Naproxcinod

Investigational
Matched Synonyms: … (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester …
Matched Iupac: … 4-(nitrooxy)butyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate …

Zosuquidar

Zosuquidar is a compound of antineoplastic drug candidates currently under development. It is now in "Phase 3" of clinical tests in the United States. Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.
Investigational
Matched Iupac: … (2R)-1-{4-[(2R,4S,11R)-3,3-difluorotetracyclo[10.4.0.0^{2,4}.0^{5,10}]hexadeca-1(16),5,7,9,12,14-hexaen ... -11-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol …

CCX915

CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical trial for the treatment of Multiple Sclerosis and Neurologic Disorders. The CCR2 receptor is thought to be of central importance to inflammatory diseases, such as multiple sclerosis (MS), Type II diabetes and...
Investigational
Matched Description: … CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical …

Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol

Experimental

{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid

This compound belongs to the nitrofurans. These are compounds containing a furan ring which bears a nitro group. It targets the protein aldose reductase.
Experimental

2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose

Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …

(4R)-7-Aza-7,8-dihydrolimonene

Experimental
Matched Iupac: … (1R)-N,N,4-trimethylcyclohex-3-en-1-amine …

Ripasudil

Ripasudil, as hydrochloride hydrate (K-115), is a specifc Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor used for the treatment of glaucoma and ocular hypertension. It was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the...
Experimental
Matched Iupac: … 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Matched Salts cas: … 887375-67-9 …

(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid

Experimental
Matched Name: … (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid …
Matched Iupac: … (2S)-3-{4-[2-(9H-carbazol-9-yl)ethoxy]phenyl}-2-ethoxypropanoic acid …

methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate

Experimental
Matched Name: … methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate …
Matched Iupac: … methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-oxopentanoate …

3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID

Experimental
Matched Name: … 3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-[(4-chlorophenyl)sulfamoyl]thiophene-2-carboxylic acid …

SL017

SL017 formulated as a topical gel, has been combined with a widely available light source for permanent removal of unwanted hair and for treatment of actinic keratosis
Investigational

Sivifene

Investigational
Matched Iupac: … 4-{[2-(2,4-dinitrophenyl)hydrazin-1-ylidene](4-hydroxyphenyl)methyl}phenol …

Sulfotep

Experimental
Vet approved

SB-705498

SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
Investigational
Matched Iupac: … 1-(2-bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-3-yl]urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Safingol

Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational

SB-649868

SB-649868 is under investigation in clinical trial NCT01030939 (Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers).
Investigational
Matched Iupac: … N-{[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl}-1-benzofuran-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Saltikva

Investigational

FLX475

FLX475 is a small molecule CCR4 antagonist being investigated for the treatment of cancer.
Investigational

Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide

Experimental
Matched Iupac: … N-(2-hydroxyethyl)-N-[(2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexyl]nonanamide …

Methyl alpha-D-mannoside

Experimental
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol …

N-omega-propyl-L-arginine

Experimental
Matched Iupac: … (E)-[amino({[(4S)-4-amino-4-carboxybutyl]amino})methylidene](propyl)azanium …
Displaying drugs 7676 - 7700 of 12984 in total