Displaying drugs 751 - 775 of 962 in total
Ifinatamab deruxtecan
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA ... .1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA. …
Larcaviximab
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c4g7 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c4g7 heavy chain), disulfide …
AAV9/MFSD8
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … MFSD8 gene for expression of active human major facilitator superfamily domain containing 8 ... An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/ …
Matched Description: … CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human …
Matched Description: … CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Efmarodocokin alfa
Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Synonyms: … HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10 ... INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
CTCE-9908
Investigational
Matched Synonyms: … SDF-1 (108) Lysine Dlmer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lanimostim
Investigational
Matched Synonyms: … 4-221-Colony-stimulating factor 1 (human clone p3ACSF-69 reduced) …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human intercellular adhesion molecule icam-1) (human monoclonal bi-505 .gamma ... Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human …
Estriol
A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Description: … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the ... A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Advanced Formula Estro-Life …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Advanced Formula Estro-Life …
Retlirafusp alfa
Investigational
Matched Synonyms: … isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. ... programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with ... Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
BI-836858
Investigational
Matched Synonyms: … Fully Human Igg1 Antibody Specific For Cd33 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Col-Treg
Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Synonyms: … Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen …
Matched Description: … Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type …
Matched Description: … Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type …
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Synonyms: … Human albumin I-125 ... Human serum albumin I-125 ... Iodinated (125I) human serum albumin …
Matched Description: … iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and …
Matched Description: … iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Maplirpacept
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Aripiprazole
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …
Sargramostim
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Synonyms: … Recombinant human granulocyte-macrophage colony stimulating factor …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Glucagon
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643]
Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon, human …
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AD-114
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
Insulin-like growth factor II
The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Human oligopeptide-24 ... Human insulin-like growth factor II ... Insulin-like growth factor II (human) …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 751 - 775 of 962 in total