Displaying drugs 8201 - 8225 of 9659 in total
Ivarmacitinib
Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the treatment of various immuno-inflammatory conditions. While ivarmactinib has yet to receive marketing authorization, as of February 2022 clinical trials are ongoing or completed evaluating its use in atopic dermatitis,[L40604,L40619,L40629] ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis,...
Experimental
Investigational
Matched Iupac: … (3aR,5S,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]-octahydrocyclopenta …
Matched Salts cas: … 1639419-51-4 …
Matched Salts cas: … 1639419-51-4 …
Dextrorphan
Experimental
Matched Synonyms: … (+)-N-methylmorphinan-3-ol ... d-3-hydroxy-N-methylmorphinan …
Matched Iupac: … (1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … (1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Nendratareotide uzatansine
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …
Obinepitide
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Iupac: … ]amino}-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene] ... -hydroxypropylidene]amino}-3-hydroxybutanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-4-{[(1S)-1-{ ... methylpentylidene]amino}-4-carboxybutanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3-methylbutylidene ... amino}-3-carboxy-1-hydroxypropylidene]amino}-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-1 ... 1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2R)-1-{[(1S)-4-carbamimidamido …
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Vobramitamab duocarmazine
Vobramitamab duocarmazine is under investigation in clinical trial NCT05551117 (A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors).
Investigational
Lomvastomig
Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational
Matched Synonyms: … Anti-pd-1/tim-3 bispecific antibody ro7121661 …
L-Dilinoleoyllecithin
Experimental
Matched Synonyms: … 1,2-dilinoleoyl-sn-glycero-3-phosphocholine ... 1,2-di-O-linoleoyl-sn-glycero-3-phosphocholine ... 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine …
Relmacabtagene autoleucel
Investigational
(1R)-2-[(CYANOMETHYL)AMINO]-1-({[2-(DIFLUOROMETHOXY)BENZYL]SULFONYL}METHYL)-2-OXOETHYL MORPHOLINE-4-CARBOXYLATE
Experimental
Matched Name: … (1R)-2-[(CYANOMETHYL)AMINO]-1-({[2-(DIFLUOROMETHOXY)BENZYL]SULFONYL}METHYL)-2-OXOETHYL MORPHOLINE-4-CARBOXYLATE …
Matched Iupac: … (1R)-1-[(cyanomethyl)carbamoyl]-2-{[2-(difluoromethoxy)phenyl]methanesulfonyl}ethyl morpholine-4-carboxylate …
Matched Iupac: … (1R)-1-[(cyanomethyl)carbamoyl]-2-{[2-(difluoromethoxy)phenyl]methanesulfonyl}ethyl morpholine-4-carboxylate …
N-[(1S)-2-{[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]amino}-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4-carboxamide
Experimental
Matched Name: … (1S)-2-{[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]amino}-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4- …
Matched Iupac: … (2S)-N-[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]-3-cyclohexyl-2-[(morpholine-4-carbonyl)amino]propanamide …
Matched Iupac: … (2S)-N-[(1R)-2-(benzyloxy)-1-cyano-1-methylethyl]-3-cyclohexyl-2-[(morpholine-4-carbonyl)amino]propanamide …
3-(BUTYLSULPHONYL)-PROPANOIC ACID
Experimental
Matched Name: … 3-(BUTYLSULPHONYL)-PROPANOIC ACID …
Matched Iupac: … 3-(butane-1-sulfonyl)propanoic acid …
Matched Iupac: … 3-(butane-1-sulfonyl)propanoic acid …
24-Homo-1,25-dihydroxyvitamin D3
24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue.
Experimental
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-7-hydroxy-7-methyloctan-2-yl]-7a-methyl-octahydro-1H-inden-4 ... -ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol …
3-O-Methylfructose in Linear Form
Experimental
Matched Name: … 3-O-Methylfructose in Linear Form …
Matched Iupac: … (3S,4R,5R)-1,4,5,6-tetrahydroxy-3-methoxyhexan-2-one …
Matched Iupac: … (3S,4R,5R)-1,4,5,6-tetrahydroxy-3-methoxyhexan-2-one …
N-(3-carboxypropanoyl)-L-norvaline
N-(3-carboxypropanoyl)-L-norvaline is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom. This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase.
Experimental
Matched Name: … N-(3-carboxypropanoyl)-L-norvaline …
Matched Iupac: … (2S)-2-(3-carboxypropanamido)pentanoic acid …
Matched Description: … N-(3-carboxypropanoyl)-L-norvaline is a solid. …
Matched Iupac: … (2S)-2-(3-carboxypropanamido)pentanoic acid …
Matched Description: … N-(3-carboxypropanoyl)-L-norvaline is a solid. …
(1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL
Experimental
Matched Name: … (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …
Melanoma antigen recognized by T-cells 1
Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery).
Investigational
Raffinose
Investigational
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-({[(2S,3R,4S …
Depelestat
Investigational
Selenocysteine
A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. [PubChem]
Experimental
Matched Synonyms: … 3-selenyl-L-alanine …
Matched Iupac: … (2R)-2-amino-3-selanylpropanoic acid …
Matched Iupac: … (2R)-2-amino-3-selanylpropanoic acid …
Plamotamab
Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)).
Investigational
(R)-2-Hydroxy-3-Sulfopropanoic Acid
Experimental
Matched Name: … (R)-2-Hydroxy-3-Sulfopropanoic Acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …
(2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Matched Name: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL
Experimental
Displaying drugs 8201 - 8225 of 9659 in total