Displaying drugs 8201 - 8225 of 10632 in total
Icariin
Icariin has been investigated for the basic science of the Pharmacokinetic Profile of Icariin in Humans.
Investigational
Matched Iupac: … 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl ... )oxan-2-yl]oxy}-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one …
Hidrosmin
Experimental
Matched Iupac: … 2-(3-hydroxy-4-methoxyphenyl)-5-(2-hydroxyethoxy)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R ... ,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Sonolisib
Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid Tumors, Advanced BRAF-mutant Cancers, and Non Small Cell Lung Cancer (NSCLC), among others.
Investigational
Matched Iupac: … -5,9,14-trioxo-4-oxatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(10),7-dien-17-yl acetate ... (2R,3S,6E,11R,15S,17R)-6-{[bis(prop-2-en-1-yl)amino]methylidene}-8-hydroxy-3-(methoxymethyl)-2,15-dimethyl …
18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE
Experimental
Matched Iupac: … 7-chloro-11,17-dioxa-2,4,20,22-tetraazatricyclo[16.3.1.0^{5,10}]docosa-1(22),5(10),6,8,18,20-hexaen-3 …
2'-O-Acetyl Adenosine-5-Diphosphoribose
Experimental
Matched Name: … 2'-O-Acetyl Adenosine-5-Diphosphoribose …
Matched Iupac: … ,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid ... [({[(2R,3R,4R,5S)-4-(acetyloxy)-3,5-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R …
Matched Iupac: … ,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid ... [({[(2R,3R,4R,5S)-4-(acetyloxy)-3,5-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R …
1,4-dithio-alpha-D-glucopyranose
Experimental
N-Cyclohexyl-N'-(4-Iodophenyl)Urea
Experimental
Matched Name: … N-Cyclohexyl-N'-(4-Iodophenyl)Urea …
Matched Iupac: … 3-cyclohexyl-1-(4-iodophenyl)urea …
Matched Iupac: … 3-cyclohexyl-1-(4-iodophenyl)urea …
4,7-Dimethyl-[1,10]Phenanthroline
Experimental
4-O-methyl-beta-D-glucuronic acid
Experimental
Matched Name: … 4-O-methyl-beta-D-glucuronic acid …
Matched Iupac: … (2S,3S,4R,5R,6R)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,3S,4R,5R,6R)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid …
4-O-{4,6-O-[(1S)-1-Carboxyethylidene]-β-D-mannopyranosyl}-D-glucopyranuronic acid
Experimental
Matched Name: … 4-O-{4,6-O-[(1S)-1-Carboxyethylidene]-β-D-mannopyranosyl}-D-glucopyranuronic acid …
Matched Iupac: … (2S,3S,4R,5R)-3-{[(2S,4aR,6S,7S,8R,8aS)-2-carboxy-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3 …
Matched Iupac: … (2S,3S,4R,5R)-3-{[(2S,4aR,6S,7S,8R,8aS)-2-carboxy-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3 …
4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE
Experimental
Matched Name: … 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE …
Matched Iupac: … 1-(4-methylpiperazin-1-yl)-3-(4-sulfamoylphenyl)thiourea …
Matched Iupac: … 1-(4-methylpiperazin-1-yl)-3-(4-sulfamoylphenyl)thiourea …
Etrolizumab
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration and retention of intestinal-homing lymphocytes.[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some...
Investigational
1-(2-Ethanone)-2-Hydroxy-2-(1-Amino-2-Methyl-2-Ethanol)-4-(2-Dimethyl)Ethane-Imidazoline-5-One;Chromophore (Thr-Leu-Gly)
Experimental
Matched Name: … 1-(2-Ethanone)-2-Hydroxy-2-(1-Amino-2-Methyl-2-Ethanol)-4-(2-Dimethyl)Ethane-Imidazoline-5-One;Chromophore …
Matched Iupac: … 2-[(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4-(2-methylpropyl)-5-oxo-2,5-dihydro-1H-imidazol …
Matched Iupac: … 2-[(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4-(2-methylpropyl)-5-oxo-2,5-dihydro-1H-imidazol …
Alpha-Ribazole-5'-Phosphate Derivative
Experimental
Matched Name: … Alpha-Ribazole-5'-Phosphate Derivative …
Matched Iupac: … {[(2R,3S,4R,5S)-5-(1H-1,3-benzodiazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4R,5S)-5-(1H-1,3-benzodiazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
N-Pyridoxyl-Threonine-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-Threonine-5-Monophosphate …
Matched Iupac: … 3-hydroxy-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]butanoic acid …
Matched Iupac: … 3-hydroxy-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]butanoic acid …
(10R)-10-formyl-5,8,10-trideazafolic acid
Experimental
Matched Iupac: … (2S)-2-({4-[(1R)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic …
Phenolsulfonic acid
Experimental
Matched Synonyms: … 4-Sulfophenol ... 4-hydroxybenzenesulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Matched Salts cas: … 10580-19-5 …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Matched Salts cas: … 10580-19-5 …
JBI-802
Investigational
Matched Synonyms: … N-hydroxy-4-((4-((((1R,2S)-2-phenylcyclopropyl) amino)methyl)-1H-pyrazol-1-yl)methyl)benzamide hydrogen …
t-Butylhydroquinone
Experimental
Saruplase
Experimental
N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL]
Experimental
Matched Iupac: … (hydroxymethyl)oxolan-3-yl]hexanediamide ... 4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-N'-[(3S,5S)-5- …
4-isothioureidobutyronitrile
Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer.
Investigational
Matched Name: … 4-isothioureidobutyronitrile …
Matched Iupac: … 4-(carbamimidoylsulfanyl)butanenitrile …
Matched Iupac: … 4-(carbamimidoylsulfanyl)butanenitrile …
(4-(trifluoromethoxy)phenyl)urea
Experimental
Matched Name: … (4-(trifluoromethoxy)phenyl)urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
ATG-101
ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Displaying drugs 8201 - 8225 of 10632 in total