Displaying drugs 8276 - 8300 of 10084 in total
BMS-817399
BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).
Investigational
Matched Iupac: … 1-[(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3- …
Vecabrutinib
Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).
Investigational
Matched Iupac: … (3R,3'R,4'S)-1'-(6-amino-5-fluoropyrimidin-4-yl)-3-{[3-chloro-5-(trifluoromethyl)phenyl]amino}-2-oxo- ... [1,3'-bipiperidine]-4'-carboxamide …
UCB7362
UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria. Plasmepsins are aspartyl proteases produced by the malaria parasite Plasmodium falciparum, and PMX is considered to be essential for parasite egress and invasion. UCB7362 is estimated to achieve a significant reduction in asexual blood-stage...
Investigational
Matched Iupac: … N-{2-chloro-3-[(4S)-2-imino-4-methyl-1-[(2S,4S)-2-methyloxan-4-yl]-6-oxo-1,3-diazinan-4-yl]phenyl}-3- …
Furethidine
Experimental
Illicit
Matched Iupac: … ethyl 1-{2-[(oxolan-2-yl)methoxy]ethyl}-4-phenylpiperidine-4-carboxylate …
Argininosuccinate
Experimental
Matched Iupac: … (2R)-2-[(E)-N''-[(4S)-4-amino-4-carboxybutyl]carbamimidamido]butanedioic acid …
Clefamide
Experimental
Matched Iupac: … 2,2-dichloro-N-(2-hydroxyethyl)-N-{[4-(4-nitrophenoxy)phenyl]methyl}acetamide …
AIM-102
AIM-102 is under investigation in clinical trial NCT01501942 (Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic Asthma).
Investigational
Matched Iupac: … (4R)-4-[(2R)-2-amino-3-cyclohexylpropanamido]-4-[(carboxymethyl)carbamoyl]butanoic acid …
Sovaprevir
Sovaprevir has been investigated for the treatment of Hepatitis C, Chronic.
Investigational
Matched Iupac: … ]-2-ethenylcyclopropyl]-4-[(7-methoxy-2-phenylquinolin-4-yl)oxy]pyrrolidine-2-carboxamide ... (2S,4R)-1-[(2S)-2-tert-butyl-4-oxo-4-(piperidin-1-yl)butanoyl]-N-[(1R,2S)-1-[(cyclopropanesulfonyl)carbamoyl …
BMS-903452
BMS-903452 has been used in trials studying the treatment of Diabetes.
Investigational
Matched Iupac: … 5-chloro-4-{[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]oxy}-1-(2-fluoro-4-methanesulfonylphenyl)-1,2-dihydropyridin …
Dubermatinib
Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Investigational
Matched Iupac: … 2-{[5-chloro-2-({4-[(4-methylpiperazin-1-yl)methyl]phenyl}amino)pyrimidin-4-yl]amino}-N,N-dimethylbenzene …
Nemiralisib
Nemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Iupac: … 6-(1H-indol-4-yl)-4-(5-{[4-(propan-2-yl)piperazin-1-yl]methyl}-1,3-oxazol-2-yl)-1H-indazole …
Poseltinib
Poseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis).
Investigational
Matched Iupac: … N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}furo[3,2-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide …
Oclacitinib
Investigational
Vet approved
Matched Iupac: … N-methyl-1-{4-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]cyclohexyl}methanesulfonamide …
AZD-7687
AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study).
Investigational
Matched Iupac: … 2-[(1r,4r)-4-[4-(6-carbamoyl-3,5-dimethylpyrazin-2-yl)phenyl]cyclohexyl]acetic acid …
Nolasiban
Nolasiban is under investigation in clinical trial NCT03081208 (Phase 3 Placebo Controlled Study of Nolasiban to Improve Pregnancy Rates in Women Undergoing IVF/ICSI).
Investigational
Matched Iupac: … [(2S,4Z)-4-(methoxyimino)-1-{2'-methyl-[1,1'-biphenyl]-4-carbonyl}pyrrolidin-2-yl]methanol …
Matched Description: … Nolasiban is under investigation in clinical trial NCT03081208 (Phase 3 Placebo Controlled Study of Nolasiban …
Matched Description: … Nolasiban is under investigation in clinical trial NCT03081208 (Phase 3 Placebo Controlled Study of Nolasiban …
Phenacetin
Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Withdrawn
Matched Iupac: … N-(4-ethoxyphenyl)acetamide …
Vanillyl alcohol
Vanillyl alcohol has been used in trials studying the treatment of Smoking.
Investigational
Matched Iupac: … 4-(hydroxymethyl)-2-methoxyphenol …
Aminomethylbenzoic acid
Aminomethylbenzoic acid may be useful as an antifibrinolytic agent .
Experimental
Matched Iupac: … 4-(aminomethyl)benzoic acid …
Aminopentamide
Experimental
Vet approved
Matched Iupac: … 4-(dimethylamino)-2,2-diphenylpentanamide …
Matched Salts cas: … 20701-77-3 …
Matched Salts cas: … 20701-77-3 …
Mitiglinide
Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Investigational
Matched Iupac: … (2S)-4-[(3aR,7aS)-octahydro-1H-isoindol-2-yl]-2-benzyl-4-oxobutanoic acid …
Allylprodine
Experimental
Illicit
Matched Iupac: … 1-methyl-4-phenyl-3-(prop-2-en-1-yl)piperidin-4-yl propanoate …
Displaying drugs 8276 - 8300 of 10084 in total