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Displaying drugs 8326 - 8350 of 11114 in total
INO-4800
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … (NCT04336410) was started on April 3, 2020, with an expected completion date of July 2021. ... INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development ... Furthermore, the antibodies produced were capable of inhibiting the binding of SARS-CoV-2 to the ACE2 …
5-hydroxynaphthalene-1-sulfonamide
Experimental
Matched Name: … 5-hydroxynaphthalene-1-sulfonamide …
Matched Iupac: … 5-hydroxynaphthalene-1-sulfonamide …
Matched Iupac: … 5-hydroxynaphthalene-1-sulfonamide …
5'-O-[(L-methionyl)-sulphamoyl]adenosine
Experimental
Matched Name: … 5'-O-[(L-methionyl)-sulphamoyl]adenosine …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-4,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy ... }sulfonyl)amino]-2-[2-(methylsulfanyl)ethyl]ethan-1-one …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-4,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy ... }sulfonyl)amino]-2-[2-(methylsulfanyl)ethyl]ethan-1-one …
N-Pyridoxyl-Glycine-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-Glycine-5-Monophosphate …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acetic acid …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acetic acid …
4-Methyl-Pyrroline-5-Carboxylic Acid
Experimental
Matched Name: … 4-Methyl-Pyrroline-5-Carboxylic Acid …
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
Matched Iupac: … (2R,3R)-3-methyl-2,3-dihydro-1H-pyrrole-2-carboxylic acid …
Tarenflurbil
Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease. It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. Aβ42 is the primary initiator of neurotoxicity and amyloid...
Investigational
Matched Synonyms: … (−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ... (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid ... (R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acid …
Matched Iupac: … (2R)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Iupac: … (2R)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Aloe vera leaf
Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Ciliary neurotrophic factor
NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is under investigation for the treatment of retinitis pigmentosa and age-related macular degeneration.
Investigational
Dulanermin
Dulanermin has been used in trials studying the treatment of Colorectal Cancer, Non-Hodgkin's Lymphoma, and Metastatic Colorectal Cancer.
Investigational
Tariquidar
Investigational
Matched Iupac: … ]quinoline-3-carboxamide ... N-[2-({4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]phenyl}carbamoyl)-4,5-dimethoxyphenyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tonabersat
Investigational
Matched Iupac: … N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
Experimental
Matched Iupac: … (4'R)-7',8'-dichloro-1,9'-dimethyl-1'-oxo-1',2',4',9'-tetrahydrospiro[piperidine-4,3'-pyrido[3,4-b]indole …
(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
Experimental
Matched Iupac: … (4'R)-7'-chloro-9'-methyl-1'-oxo-1',2',4',9'-tetrahydrospiro[piperidine-4,3'-pyrido[3,4-b]indole]-4'- …
BQ-123
BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Iupac: … 2-[(3R,6S,9R,12R,17aS)-9-[(1H-indol-3-yl)methyl]-6-(2-methylpropyl)-1,4,7,10,13-pentaoxo-3-(propan-2- …
Daphnetin
Daphnetin is under investigation in clinical trial NCT06329167 (Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery).
Investigational
Matched Synonyms: … 2h-1-benzopyran-2-one, 7,8-dihydroxy- ... 7,8-dihydroxy-2h-1-benzopyran-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Mavrilimumab
Mavrilimumab has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Avexitide
Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia).
Investigational
Matched Iupac: … {[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5- ... }-2-(1H-indol-3-yl)ethyl]carbamoyl}-3-carboxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-phenylethyl ... ]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl]carbamoyl}-4-[(2S)-2-[(2R)-2-[(2S)-6-amino-2-[ ... (2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-4-methylpentanamido]-3-hydroxypropanamido]hexanamido ... -1-yl]-2-oxoethyl}carbamoyl)methyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl …
N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE
Experimental
Matched Name: … N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE …
Matched Iupac: … methyl[(2R)-1-phenylpropan-2-yl](prop-2-en-1-yl)amine …
Matched Iupac: … methyl[(2R)-1-phenylpropan-2-yl](prop-2-en-1-yl)amine …
Dichlorvos
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved
CP-122721
CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Investigational
Matched Iupac: … (2S,3S)-N-{[2-methoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine …
BI-836858
Investigational
CLL1-CD33 compound chimeric antigen receptor T cells
Investigational
2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose
Experimental
Matched Name: … 2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose …
Matched Iupac: … (3aR,4R,5R,6R,6aS)-6-(hydroxymethyl)-2-(methylideneamino)-3aH,4H,5H,6H,6aH-cyclopenta[d][1,3]oxazole- …
Matched Iupac: … (3aR,4R,5R,6R,6aS)-6-(hydroxymethyl)-2-(methylideneamino)-3aH,4H,5H,6H,6aH-cyclopenta[d][1,3]oxazole- …
(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM
Experimental
Matched Iupac: … [2-(dodecyldimethylphosphaniumyl)-1-phosphonoethyl]phosphonic acid …
1,2-Dihydroxybenzene
Experimental
Displaying drugs 8326 - 8350 of 11114 in total