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Displaying drugs 8426 - 8450 of 11103 in total

WP-1122

WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … 3,6-di-O-acetyl-2-deoxy-D-glucopyranose ... an acetic acid diester of 2-deoxy-D-glucose …
Matched Description: … WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). …

OptPA

Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational

8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-

Experimental
Matched Name: … 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- …
Matched Iupac: … 8-[(2H-1,3-benzodioxol-5-yl)methyl]-9-butyl-9H-purin-6-amine …

6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE

Experimental
Matched Name: … 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)pyridin-2-amine …

K-00546

Experimental
Matched Synonyms: … CDK1/2 inhibitor III …
Matched Iupac: … 5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide …

Fletikumab

Fletikumab is under investigation in clinical trial NCT01038674 (Safety and Tolerability of Anti-IL-20 in Subjects With Rheumatoid Arthritis).
Investigational

Irdabisant

Irdabisant has been used in trials studying Cognitive Impairment.
Investigational
Matched Iupac: … 6-(4-{3-[(2R)-2-methylpyrrolidin-1-yl]propoxy}phenyl)-2,3-dihydropyridazin-3-one …

Selatogrel

Selatogrel is under investigation in clinical trial NCT03814200 (A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects).
Investigational
Matched Iupac: … [(2R)-3-[4-(butoxycarbonyl)piperazin-1-yl]-2-({6-[(3S)-3-methoxypyrrolidin-1-yl]-2-phenylpyrimidin-4- …

Isobutyramide

Investigational
Matched Synonyms: … 2-methylpropionamide …
Matched Iupac: … 2-methylpropanamide …

(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID

Experimental
Matched Name: … (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-benzenesulfonamido-2-methylpropyl](hydroxy)phosphoryl}propanoic …

2-Oxobutanoic Acid

Experimental
Matched Name: … 2-Oxobutanoic Acid …
Matched Iupac: … 2-oxobutanoic acid …

LY2140023

LY2140023 is an investigational drug from Lilly, which is being developed as a new treatment option for schizophrenia. LY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039. Most currently approved antipsychotic medications...
Investigational

2-Bromoacetyl Group

Experimental
Matched Name: … 2-Bromoacetyl Group …
Matched Iupac: … 2-bromoacetic acid …

2-(Sec-Butyl)Thiazole

Experimental
Matched Name: … 2-(Sec-Butyl)Thiazole …
Matched Iupac: … 2-[(2R)-butan-2-yl]-1,3-thiazole …

2-Iminiopropanoate

Experimental
Matched Name: … 2-Iminiopropanoate …
Matched Iupac: … 2-iminiumylpropanoate …

1-Methyl-2-quinolone

Experimental
Matched Name: … 1-Methyl-2-quinolone …
Matched Iupac: … 1-methyl-1,2-dihydroquinolin-2-one …

1,2-dichlorobenzene

1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound by the presence of two adjacent chlorine atoms. 1,2-dichlorobenzene is used as a precursor for agrochemicals, as a solvent for...
Experimental
Matched Synonyms: … 2-Dichlorobenzene …

Aspergillopepsin-2

Experimental
Matched Name: … Aspergillopepsin-2 …

5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE

Experimental
Matched Name: … 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE …
Matched Iupac: … -7-yl]oxy}-4-oxobutanoic acid ... 4-{[(1S,3aS,3bR,5aS,7S,9aS,9bS,11aS)-1-acetyl-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …

D-Myo-Inositol-1,4-Bisphosphate

Experimental
Matched Iupac: … {[(1R,2R,3R,4R,5R,6S)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphonic acid …

Efonidipine

Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis...
Experimental
Matched Iupac: … 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ⁵-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl …

Botaretigene sparoparvovec

Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER ... HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS ADENO-ASSOCIATED VIRUS 2 …

ANX-005

Investigational

2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine

Experimental
Matched Name: … 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …

AGIL-FA

Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein …
Displaying drugs 8426 - 8450 of 11103 in total