Displaying drugs 8451 - 8475 of 11945 in total
VG161
VG161 is an oncolytic virus therapy under investigation for the treatment of cholangiocarcinoma.
Investigational
Matched Synonyms: … Recombinant human IL12/15-PDL1B HSV-1 oncolytic virus Injection …
Adenosine-5'-Propylphosphate
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(propoxy)phosphinic acid …
7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate)
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-6,7,8,9-tetrahydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2 …
N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …
Axelopran
Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
Investigational
Matched Iupac: … 3-[(1R,3R,5S)-8-{2-[(2S)-N-(cyclohexylmethyl)-2,3-dihydroxypropanamido]ethyl}-8-azabicyclo[3.2.1]octan ... -3-yl]benzamide …
Matched Salts cas: … 949904-50-1 …
Matched Salts cas: … 949904-50-1 …
Somatorelin
Somatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.
Investigational
Matched Synonyms: … GHRH(1-44)NH2 ... GHRH(1-44) AMIDE ... growth hormone releasing hormone, 1-44 human amide …
PP-F11N lutetium Lu-177
Investigational
Matched Iupac: … (177Lu)lutetium(3+) 2-[4-({[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-[({ ... [(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-carboxyethyl]carbamoyl}pentyl ... ]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-(4-hydroxyphenyl)ethyl]carbamoyl}ethyl ... ]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl ... ]carbamoyl}-3-carboxypropyl]carbamoyl}-3-carboxypropyl]carbamoyl}methyl)-7,10-bis(carboxylatomethyl)- …
7-methyl-7,8-dihydroguanosine-5'-diphosphate
Experimental
Matched Iupac: … -2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid ... [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan …
2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL
Experimental
Matched Name: … 2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL …
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(octylsulfanyl)oxane-3,4,5-triol …
Matched Iupac: … (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(octylsulfanyl)oxane-3,4,5-triol …
LG-100268
LG-100268 is a retinoid X receptor (RXR) selective compound.
Experimental
Matched Iupac: … 6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CRA_10433
Experimental
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-(cyclopentyloxy)benzen-1-olate …
SD118
SD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy for neuropathic pain.
Investigational
ADX-10061
ADX10061 is a potent, selective antagonist of the dopamine D1 receptor. It is developed by Addex Pharmaceuticals for the treatment of nicotine dependence.
Investigational
Matched Iupac: … (5S)-5-(2,3-dihydro-1-benzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
SR 121463
SR 121463 is a nonpeptide aquaretic compound with potent selective antagonism of the vasopressin V2 (V1b) receptor subtype. It is a candidate for control of hyponatremia and in the treatment of syndrome of inappropriate secretion of anti-diuretic hormone (SIADH).
Investigational
SR 140333
SR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Investigational
Matched Iupac: … 1-{2-[(3R)-3-(3,4-dichlorophenyl)-1-{2-[3-(propan-2-yloxy)phenyl]acetyl}piperidin-3-yl]ethyl}-4-phenyl ... -1-azabicyclo[2.2.2]octan-1-ium chloride …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ORM-12741
ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … (2S,3S)-3-(methoxymethyl)-3-methyl-17-oxa-7-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),11,13,15 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
PAC-14028
PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.
Investigational
Matched Iupac: … (2E)-N-[(1R)-1-(3,5-difluoro-4-methanesulfonamidophenyl)ethyl]-3-[2-propyl-6-(trifluoromethyl)pyridin ... -3-yl]prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CP-195543
CP-195,543 has been used in trials studying the treatment of Arthritis, Rheumatoid.
Investigational
Matched Iupac: … 2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-1-benzopyran-7-yl]-4-(trifluoromethyl)benzoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
DCFBC F-18
DCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Investigational
Matched Iupac: … (2S)-2-({[(1R)-1-carboxy-2-({[4-(¹⁸F)fluorophenyl]methyl}sulfanyl)ethyl]carbamoyl}amino)pentanedioic …
ARC-19499
ARC-19499 is under investigation in clinical trial NCT01191372 (First-in-Human and Proof-of-Mechanism Study of ARC19499 Administered to Hemophilia Patients).
Investigational
SOR-C13
SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).
Investigational
Matched Iupac: … -1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]carbamoyl}-3-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl ... 2-{[(1S)-4-carbamimidamido-1-carboxybutyl]carbamoyl}pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]carbamoyl ... (4S)-4-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)- ... }-2-carboxyethyl]carbamoyl}-2-methylpropyl]carbamoyl}pentyl]carbamoyl}-2-hydroxyethyl]carbamoyl}pyrrolidin …
Bfpet F-18
Bfpet F-18 is under investigation in clinical trial NCT03265431 (Evaluation of PET/MR in Patients Selected for Ablation Therapy).
Investigational
PD-173952
PD-173952 is a potent Myt1 kinase inhibitor.
Investigational
Matched Iupac: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[4-(morpholin-4-yl)phenyl]imino}-2H,3H,7H,8H-pyrido[2,3-d]pyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 8451 - 8475 of 11945 in total