Displaying drugs 8451 - 8475 of 11462 in total
R1204
R1204 is G-protein-coupled receptor modulator. It is developed for the treatment of depression.
Investigational
CAD106
CAD106 is an immunotherapeutic product in development for the treatment of Alzheimer's disease. It is designed to induce antibodies against the beta-amyloid-protein that inhibit the formation of plaques in the brain of Alzheimer's disease patients.
Investigational
PDPSC18
PDPSC18 is therapeutic DNA vaccine designed to fight chronic infections with the Hepatitis B virus, entering phase I clinical trials.
Investigational
CYC116
CYC116 is a novel anticancer compound with a unique target profile involving both cell cycle and angiogenesis inhibition mechanisms. In preclinical studies, CYC116 has demonstrated antitumor activity in both solid tumors and hematological cancers.
Cyclacel's small molecule investigational drug, CYC116, is the third orally-available Cyclacel drug to enter development, which...
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Actelion-1
Actelion-1 is a tissue-targeting Endothelin Receptor Antagonist that has been discovered by Actelion Pharmaceuticals.
Investigational
Matched Name: … Actelion-1 …
Matched Description: … Actelion-1 is a tissue-targeting Endothelin Receptor Antagonist that has been discovered by Actelion …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Actelion-1 is a tissue-targeting Endothelin Receptor Antagonist that has been discovered by Actelion …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BNC105
Investigational
Matched Iupac: … {[6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)-1-benzofuran-7-yl]oxy}phosphonic acid …
ALGRX 1207
ALGRX 1207 is a topical local anesthetic that acts by binding to the fast sodium channel. ALGRX 1207 entered clinical trials for cutaneous neuropathic pain, such as chemotherapy-induced neuropathy, in 2006. It was being developed by Anesiva, but trials have halted.
Investigational
Gold Au-198
Experimental
BBV152
BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) or a novel TLR7/8 agonist adsorbed gel....
Investigational
Matched Description: … Thus, as of July 2020, BBV152 is in Phase 1/2 clinical trials assessing safety and immunogenicity in …
IMM101
IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma [PMID: 21930686; PMID: 30107850; PMID: 27599039]. Studies with IMM-101 showed the vaccine’s ability to stimulate cancer patients’ immune systems to help...
Investigational
MEM136
Investigational
AIC100
Investigational
ATX-F8-117
ATX-F8-117 is an investigational peptide derived from Factor VIII. Developed by Apitope, it is being investigated for the treatment of hemophilia A.
Investigational
FLT190
FLT190 is a recombinant adeno-associated viral vector serotype S3 containing DNA encoding for human alpha-galactosidase A.
Investigational
CTX120
CTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.
Investigational
CTX110
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
SLN124
SLN124 is a synthetic double-stranded siRNA oligonucleotide directed against TMPRSS6 mRNA and covalently linked to a ligand containing 3 N-acetylgalactosamine residues.
Investigational
Matched Description: … double-stranded siRNA oligonucleotide directed against TMPRSS6 mRNA and covalently linked to a ligand containing 3 …
MBP134
MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).
Investigational
Matched Synonyms: … Two immunoglobulin subclass 1 (IgG1) human monoclonal antibodies that target the Sudan ebolavirus glycoprotein …
Flavin-adenine dinucleotide-N5-isobutyl ketone
Experimental
Matched Iupac: … 9-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4S)-5-[7,8-dimethyl-5-(2-methylpropanoyl)-4-oxido-2-oxo-1H,2H,5H,10H-benzo …
Alisertib
Alisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
Investigational
Matched Iupac: … 4-{[13-chloro-10-(2-fluoro-6-methoxyphenyl)-3,5,9-triazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2,4,6,9,11,13 ... -heptaen-4-yl]amino}-2-methoxybenzoic acid …
Matched Salts cas: … 1208255-63-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1208255-63-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ceftiofur
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl) ... methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Nona-arginine
Nona-arginine is under investigation in clinical trial NCT00264706 (PolyArginine Treated vEiN grafTs (PATENT)).
Investigational
3'-phospho-5'-adenylyl sulfate
3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process...
Experimental
Matched Synonyms: … 3'-phosphoadenylyl sulfate ... 3'-phosphoadenosine 5'-phosphosulfate …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … 3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … 3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters …
(R)-acetoin
A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.
Experimental
Matched Synonyms: … (R)-3-hydroxy-2-butanone ... (R)-3-hydroxybutan-2-one …
Matched Iupac: … (3R)-3-hydroxybutan-2-one …
Matched Iupac: … (3R)-3-hydroxybutan-2-one …
Bismuth cation
Experimental
Matched Synonyms: … bismuth(3+) ... bisumth(3+) ion …
Matched Iupac: … bismuth(3+) ion …
Matched Iupac: … bismuth(3+) ion …
Displaying drugs 8451 - 8475 of 11462 in total