Displaying drugs 8476 - 8500 of 11035 in total
Fazpilodemab
Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Darusentan
Darusentan is a selective endothelin ETA receptor antagonist. It is being evaluated as a treatment for congestive heart failure and hypertension.
Investigational
Matched Iupac: … (2S)-2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
TAS-108
Investigational
Matched Iupac: … methyl]-2-methoxyphenoxy}ethyl)-9,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-5- …
Setipiprant
Setipiprant has been investigated for the treatment of Seasonal Allergic Rhinitis.
Investigational
Matched Iupac: … 2-[8-fluoro-2-(naphthalene-1-carbonyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl]acetic acid …
Bromochlorosalicylanilide
Experimental
Matched Iupac: … 5-bromo-N-(4-chlorophenyl)-2-hydroxybenzamide …
Edotreotide
Investigational
Matched Iupac: … 1,3-dihydroxybutan-2-yl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3- …
2-propenyl-N-acetyl-neuramic acid
Experimental
Matched Iupac: … (2R,4S,5R,6R)-5-acetamido-4-hydroxy-2-(prop-2-en-1-yl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic …
6-Hydro-1-Methyladenosine-5'-Monophosphate
Experimental
Matched Name: … 6-Hydro-1-Methyladenosine-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methyl-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methyl-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic …
N,N-[2,5-O-dibenzyl-glucaryl]-DI-[valinyl-aminomethanyl-pyridine]
Experimental
Matched Iupac: … (2R,3R,4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N,N'-bis[(1S)-2-methyl-1-{[(pyridin-2-yl)methyl]carbamoyl …
Dihydromorphine
A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Experimental
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10 …
Pantoyl Adenylate
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R)-2,4-dihydroxy-3,3- …
Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
Experimental
Matched Name: … Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
7-Methyl-7,8-dihydroguanosine 5'-(dihydrogen phosphate)
Experimental
Matched Name: … 7-Methyl-7,8-dihydroguanosine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-6,7,8,9-tetrahydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl] …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-6,7,8,9-tetrahydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl] …
Phosphoaminophosphonic Acid-Adenylate Ester
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]
Experimental
Matched Iupac: … ({[({[(2S,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Description: … 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. …
Matched Description: … 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. …
Trehalose
Cabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
Investigational
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …
Kitasamycin
Kitasamycin is a macrolide antibiotic derived from Streptomyces kitasatoensis.
Experimental
Matched Iupac: … (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16 ... methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate ... -dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2- …
Nesbuvir
Nesbuvir has been investigated for the treatment of Hepatitis C.
Investigational
Matched Iupac: … 5-cyclopropyl-2-(4-fluorophenyl)-6-[N-(2-hydroxyethyl)methanesulfonamido]-N-methyl-1-benzofuran-3-carboxamide …
Veldoreotide
Somatoprim is under investigation for the treatment of Acromegaly.
Investigational
Matched Iupac: … -[(3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3,18-dibenzyl-6-[(1R)-1-hydroxyethyl]-12,15-bis[(1H-indol-3- …
Sulforaphane
Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Investigational
Matched Synonyms: … (R)-sulforaphane …
Matched Iupac: … 1-isothiocyanato-4-[(R)-methanesulfinyl]butane …
Matched Iupac: … 1-isothiocyanato-4-[(R)-methanesulfinyl]butane …
Zomepirac
Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Withdrawn
Matched Synonyms: … 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Salts cas: … 64092-49-5 …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Salts cas: … 64092-49-5 …
4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
Experimental
Matched Name: … 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE …
Matched Iupac: … 4-{[5-(cyclohexyloxy)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzene-1-sulfonamide …
Matched Iupac: … 4-{[5-(cyclohexyloxy)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzene-1-sulfonamide …
Avicin D
Investigational
Matched Iupac: … (2S,3R,4S,5S,6R)-3-{[(2S,3R,4S,5S,6S)-5-{[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy ... ,6R)-4,5-dihydroxy-6-methyl-3-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}oxan-2-yl]oxy}methyl)-3-acetamido ... }-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl (3S,4aR,5R,6aS,6bR,8aR,10S,12aR,12bR,14bS)-3-{[(2E,6R)-6-{ ... methyloxan-2-yl]oxy}-2-(hydroxymethyl)-6-methylocta-2,7-dienoyl]oxy}-10-{[(2R,3R,4R,5S,6R)-6-({[(2R,3R,4S,5R ... [(2S,3R,4R,5S,6R)-3,4-dihydroxy-5-{[(2E,6R)-6-hydroxy-2-(hydroxymethyl)-6-methylocta-2,7-dienoyl]oxy} …
N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide
Experimental
Matched Synonyms: … 2-[2-Chloro-5-(trifluoromethyl)phenyl]-1-(diaminomethylene)guanidine …
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Dinalbuphine sebacate
Dinalbuphine sebacate is under investigation in clinical trial NCT02468128 (A Study of Intramuscular Sebacoyl Dinalbuphine Ester for Post-Hemorrhoidectomy Pain Management).
Investigational
Matched Iupac: … (1S,5R,13R,14S,17S)-4-(cyclobutylmethyl)-14,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17 ... }.0^{7,18}]octadeca-7(18),8,10-trien-10-yl (1S,5R,13R,14S,17S)-4-(cyclobutylmethyl)-14,17-dihydroxy-12 …
Displaying drugs 8476 - 8500 of 11035 in total