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Displaying drugs 8576 - 8600 of 10974 in total
alpha-Naphthoflavone
Experimental
Matched Synonyms: … 2-phenyl-4H-naphtho(1,2-b)pyran-4-one …
Matched Iupac: … 2-phenyl-4H-benzo[h]chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-phenyl-4H-benzo[h]chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cetyl ethylhexanoate
Cetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. It is present in cosmetic products as a skin conditioning agent and emollient.
Experimental
Matched Synonyms: … Cetyl 2-ethylhexanoate ... Hexadecyl 2-ethylhexanoate …
Matched Iupac: … hexadecyl 2-ethylhexanoate …
Matched Description: … Cetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. …
Matched Iupac: … hexadecyl 2-ethylhexanoate …
Matched Description: … Cetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. …
Denecimig
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Lerociclib
Lerociclib is under investigation in clinical trial NCT02983071 (G1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-positive, Her2-negative Locally Advanced or Metastatic Breast Cancer).
Investigational
Matched Iupac: … 12'-({5-[4-(propan-2-yl)piperazin-1-yl]pyridin-2-yl}amino)-2',5',11',13'-tetraazaspiro[cyclohexane-1,3 …
Ubamatamab
Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).
Investigational
Icotinib
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)
Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a “May Proceed” from the US FDA to conduct a Phase I study for the...
Experimental
Investigational
Matched Iupac: … N-(3-ethynylphenyl)-7H,8H,10H,11H,13H,14H-1,4,7,10-tetraoxacyclododeca[2,3-g]quinazolin-4-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
N-Acetylproline
Experimental
Matched Synonyms: … (2S)-1-acetylpyrrolidine-2-carboxylic acid ... (S)-1-acetylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-acetylpyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-acetylpyrrolidine-2-carboxylic acid …
Brazikumab
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
gamma-Glutamylcysteine
Experimental
Matched Synonyms: … 5-L-Glutamyl-L-cysteine …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butanoic acid …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butanoic acid …
Ergidina
Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Allogeneic ABCB5-positive limbal stem cells
Investigational
Isobutyric acid
Experimental
Matched Synonyms: … 2-Methylpropanoate ... 2-methyl-propionic acid ... 2-Methylpropionsäure …
Matched Iupac: … 2-methylpropanoic acid …
Matched Iupac: … 2-methylpropanoic acid …
Imazaquin
Experimental
Matched Iupac: … 2-[(4R)-4-methyl-5-oxo-4-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]quinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ethyl pyruvate
CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Investigational
Matched Synonyms: … Ethyl 2-oxopropanoate ... Ethyl 2-oxopropionate ... 2-oxopropanoic acid ethyl ester …
Matched Iupac: … ethyl 2-oxopropanoate …
Matched Iupac: … ethyl 2-oxopropanoate …
Butanilicaine
Experimental
Matched Synonyms: … 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide ... 2-(Butylamino)-6'-chloro-o-acetoluidide ... 2-Butylamino-6'-chloro-o-acetotoluidide …
Matched Iupac: … 2-(butylamino)-N-(2-chloro-6-methylphenyl)acetamide …
Matched Iupac: … 2-(butylamino)-N-(2-chloro-6-methylphenyl)acetamide …
Ceramide AP
Experimental
Matched Synonyms: … phytosphingosine-2-hydroxy-18:0 ... N-2-hydroxystearoyl-phytosphingosine ... N-(2-hydroxyoctadecanoyl)phytoceramide …
Matched Iupac: … 2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadecanamide …
Matched Iupac: … 2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadecanamide …
Tuaminoheptane
Experimental
Matched Synonyms: … 2-Heptanamine ... 2-Aminoheptane ... 2-Heptylamine …
Matched Iupac: … heptan-2-amine …
Matched Salts cas: … 6411-75-2 …
Matched Iupac: … heptan-2-amine …
Matched Salts cas: … 6411-75-2 …
Saposin C
Saposin C is a lysosomal protein. Recombinant, non-glycosylated Saposin C is an active ingredient of BXQ-350, which is a novel, investigational anti-neoplastic therapy. BXQ-350 consists of Saposin C and the phospholipid dioleoylphosphatidyl-serine (DOPS), a phospholipid located on cell membranes.
Investigational
TG4010
A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory...
Investigational
Matched Description: … (IL-2) with potential immunostimulating and antineoplastic activities. ... Expression of IL-2 augments the specific CTL response against MUC1 expressing cells. [L5191] ... comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 …
Levopropoxyphene
Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. This drug presented different dosages and it was administered...
Withdrawn
Matched Iupac: … (2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
CN-105
CN-105 is a neuroprotective pentapeptide with the sequence Acetyl-Valine-Serine-Arginine-Arginine-Arginine-NH2 (Ac-VSRRR- NH2).
Investigational
Matched Iupac: … (2S)-5-carbamimidamido-2-[(2S)-5-carbamimidamido-2-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2S)-2-acetamido ... -3-methylbutanamido]-3-hydroxypropanamido]pentanamido]pentanamido]pentanamide …
1-Beta-Ribofuranosyl-1,3-Diazepinone
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,3-dihydro-1H-1,3-diazepin-2-one …
Coenzyme A persulfide
Coenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-({2-[(2-disulfanylethyl)carbamoyl]ethyl}carbamoyl ... -3-yl]oxy}phosphonic acid ... )-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vapreotide
Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Experimental
Investigational
Matched Iupac: … (2R)-2-amino-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl ... ]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2 ... -yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-phenylpropanamide …
Displaying drugs 8576 - 8600 of 10974 in total