Displaying drugs 8651 - 8675 of 9671 in total
Famitinib
Famitinib has been used in trials studying the treatment of Colorectal Cancer, Renal Cell Cancer, Colorectal Cancer Recurrent, Colorectal Cancer Metastatic, and Metastatic Renal Cell Cancer, among others.
Investigational
Matched Iupac: … (3Z)-3-({5-[2-(diethylamino)ethyl]-3-methyl-4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2-yl}methylidene …
TOP-1288
TOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis).
Investigational
Matched Iupac: … 3-({4-[(4-{[(5-tert-butyl-3-methanesulfonamido-2-methoxyphenyl)carbamoyl]amino}naphthalen-1-yl)oxy]pyrimidin …
PF-06815345
PF-06815345 is under investigation in clinical trial NCT02654899 (Single Dose Study of PF-06815345 in Healthy Subjects).
Investigational
Matched Iupac: … (1S)-1-[5-(4-{4-[(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl]-2-fluorophenyl}-1-methyl-1H-pyrazol …
EP-217609
Investigational
Matched Iupac: … [3,4-d]imidazol-4-yl]pentanamido}-2-{4-[(3S)-3-{[(2R)-3-(4-carbamimidoylphenyl)-1-oxo-1-(piperidin-1- ... yl]oxy}-4,5-dimethoxyoxan-3-yl]oxy}-4,5-bis(sulfooxy)-2-[(sulfooxy)methyl]oxan-3-yl]oxy}-4,5-dimethoxyoxane ... (2S,3S,4S,5R,6R)-3-{[(2R,3R,4S,5R,6R)-5-{2-[2-(2-{2-[(2S)-6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno ... (2R,3S,4S,5R,6R)-2-carboxy-6-{[(2R,3R,4S,5R,6S)-4,6-dimethoxy-5-(sulfooxy)-2-[(sulfooxy)methyl]oxan-3- ... yl)propan-2-yl]carbamoyl}-3-(4-methoxy-2,3,6-trimethylbenzenesulfonamido)propanamido]butanamido}hexanamido …
Imetelstat
Imetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
Investigational
Matched Iupac: … [(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[( ... {[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-5-(4-amino-2-oxo-1,2 ... -dihydropyrimidin-1-yl)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-amino-5-(6-amino-9H-purin-9-yl)oxolan-2-yl ... sulfanyl)phosphoryl)amino]-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl 3- …
Methyclothiazide
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Withdrawn
Matched Iupac: … 6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Ecgonine
Experimental
Illicit
Matched Iupac: … (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
(S)-2-(Phosphonoxy)Caproyl-L-Leucyl-P-Nitroanilide
Experimental
Matched Iupac: … {[(1S)-1-{[(1S)-3-methyl-1-[(4-nitrophenyl)carbamoyl]butyl]carbamoyl}pentyl]oxy}phosphonic acid …
Tetrazolyl Histidine
Experimental
Matched Iupac: … (2S)-2-amino-3-[1-(2H-1,2,3,4-tetrazol-5-yl)-1H-imidazol-4-yl]propanal …
Alpha-Methyl-N-Acetyl-D-Glucosamine
Experimental
Matched Iupac: … N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-methoxyoxan-3-yl]acetamide …
Methylecgonine
Experimental
Matched Iupac: … methyl (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
OREGON GREEN 488 CARBOXYLATE
Experimental
Matched Iupac: … 4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzene-1,3-dicarboxylic acid …
Eprotirome
Eprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.
Investigational
Matched Iupac: … 2-({3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl}carbamoyl)acetic acid …
NS-2359
NS2359 is a triple monoamine re-uptake inhibitor with a new, unique drug profile expected to yield important benefits compared to existing treatments of depression. Enhancing the function of the three neurotransmitters serotonin, noradrenalin and dopamine, NS2359 has a desired "triple-mode-of-action". This mode of action is expected to produce an optimal...
Investigational
Matched Iupac: … (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane …
Triphendiol
Investigational
Matched Iupac: … (3R,4S)-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol …
Bopindolol
Bopindolol (INN) is an ester prodrug for the beta blocker pindolol.
Experimental
Matched Iupac: … 1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate …
Arotinolol
Arotinolol is an alpha- and beta-receptor blocker developed in Japan. It is a thiopropanolamine with a tertiary butyl moiety. It has been studied for its potential to be an antihypertensive therapy. Artinolol is being developed by Sumitomo Pharmaceutical Co., Ltd. and it is currently under clinical trials.
Investigational
Matched Iupac: … 5-(2-{[3-(tert-butylamino)-2-hydroxypropyl]sulfanyl}-1,3-thiazol-4-yl)thiophene-2-carboxamide …
Iferanserin
Iferanserin has been investigated for the treatment of Hemorrhoids.
Investigational
Matched Iupac: … (2E)-N-(2-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}phenyl)-3-phenylprop-2-enamide …
CG-200745
Cg200745 has been used in trials studying the treatment of Solid Tumour.
Investigational
Matched Iupac: … (2E)-N-[3-(dimethylamino)propyl]-N'-hydroxy-2-[(naphthalen-1-yloxy)methyl]oct-2-enediamide …
Tinoridine
Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
Investigational
Matched Iupac: … ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate …
Pirisudanol
Experimental
Matched Iupac: … 1-[2-(dimethylamino)ethyl] 4-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyl butanedioate …
Zipeprol
Experimental
Matched Iupac: … 1-methoxy-3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1-phenylpropan-2-ol …
Nifuratel
Experimental
Matched Iupac: … 5-[(methylsulfanyl)methyl]-3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one …
AZD-4017
AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
Investigational
Matched Iupac: … 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-(propylsulfanyl)pyridin-2-yl]piperidin-3-yl]acetic acid …
Martinostat
Martinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
Investigational
Matched Iupac: … (2E)-3-[4-({[(adamantan-1-yl)methyl](methyl)amino}methyl)phenyl]-N-hydroxyprop-2-enamide …
Displaying drugs 8651 - 8675 of 9671 in total