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Displaying drugs 8701 - 8725 of 11144 in total
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Iupac: … }-3-methylbutyl]-C-hydroxycarbonimidoyl}-3-(methylsulfanyl)propyl]-C-hydroxycarbonimidoyl}-2-(C-hydroxycarbonimidoyl ... ]amino}-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene] ... -hydroxypropylidene]amino}-3-hydroxybutanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-4-{[(1S)-1-{ ... methylpentylidene]amino}-4-carboxybutanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxy-3-methylbutylidene ... (4S)-4-({[(2S)-1-[(2S,3R)-2-{[(2S)-2-{[(2S)-2-{[(2S)-2-{[2-({[(2S)-1-[(2S)-2-{[(2S)-2-({[(2S)-1-[(2S) …
Vobramitamab duocarmazine is under investigation in clinical trial NCT05551117 (A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors).
Investigational
A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory...
Investigational
Matched Description: … (IL-2) with potential immunostimulating and antineoplastic activities. ... Expression of IL-2 augments the specific CTL response against MUC1 expressing cells. [L5191] ... comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2
Experimental
Matched Name: … 6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid …
Matched Iupac: … 6-(carboxyformamido)-1H-indole-5-carboxylic acid …
Experimental
Matched Synonyms: … phytosphingosine-2-hydroxy-18:0 ... N-2-hydroxystearoyl-phytosphingosine ... N-(2-hydroxyoctadecanoyl)phytoceramide …
Matched Iupac: … 2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadecanamide …
Experimental
Matched Synonyms: … 2-aminoethylimine …
Matched Name: … 2-Aminoethanimidic Acid …
Matched Iupac: … 2-iminoethan-1-amine …
Experimental
Matched Synonyms: … 2-Morpholinoethanamine ... N-2-Aminoethylmorpholine …
Matched Name: … 2-Morpholinoethylamine …
Matched Iupac: … 2-(morpholin-4-yl)ethan-1-amine …
Experimental
Matched Synonyms: … 1-hydroxy-2-propan-2-ylguanidine …
Matched Name: … 1-hydroxy-2-isopropylguanidine …
Matched Iupac: … (E)-N-hydroxy-N''-(propan-2-yl)guanidine …
Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Iupac: … -8-(4-hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.0⁵,¹³]trideca-2,5,7,9(13)-tetraene-3- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Synonyms: … 2-Aminobenzoesäure ... 2-carboxyaniline ... 2-aminobenzoic acid …
Matched Iupac: … 2-aminobenzoic acid …
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … L-2-(p-hydroxyphenyl)glycine …
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid …
Investigational
NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1).
Investigational
Matched Synonyms: … recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene …
Matched Description: … NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized …
Investigational
Experimental
Matched Name: … 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate …
Matched Iupac: … 2-{[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]oxy}acetic acid …
Experimental
Matched Name: … bis(5-amidino-benzimidazolyl)methanone zinc …
Matched Iupac: … 4,9}.0^{15,20}]icosa-1(13),3(11),4(9),5,7,15(20),16,18-octaene-1,3-bis(ylium) ... 7,17-bis(diaminomethyl)-12-oxo-1lambda5,3lambda5,10,14-tetraaza-2-zincapentacyclo[11.7.0.0^{3,11}.0^{ …
Coenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-({2-[(2-disulfanylethyl)carbamoyl]ethyl}carbamoyl ... -3-yl]oxy}phosphonic acid ... )-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Experimental
Investigational
Matched Iupac: … (2R)-2-amino-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl ... ]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2 ... -yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-phenylpropanamide …
Investigational
Matched Synonyms: … IL-2 variant THOR-707 ... Pegylated recombinant interleukin-2 THOR-707 …
Experimental
Matched Iupac: … N-[(2S)-1,1-diphenylpropan-2-yl]-6,7-difluoroquinazolin-4-amine …
Experimental
Matched Synonyms: … Acid Red 2 ... 2-((4-Dimethylamino)phenylazo)benzoic acid ... 2-Carboxy-4'-(dimethylamino)azobenzene …
Matched Iupac: … 2-[(1E)-2-[4-(dimethylamino)phenyl]diazen-1-yl]benzoic acid …
CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Investigational
Matched Synonyms: … Ethyl 2-oxopropanoate ... Ethyl 2-oxopropionate ... 2-oxopropanoic acid ethyl ester …
Matched Iupac: … ethyl 2-oxopropanoate …
Experimental
Matched Synonyms: … 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide ... 2-(Butylamino)-6'-chloro-o-acetoluidide ... 2-Butylamino-6'-chloro-o-acetotoluidide …
Matched Iupac: … 2-(butylamino)-N-(2-chloro-6-methylphenyl)acetamide …
Experimental
Matched Iupac: … (2S)-2-[({[(2R,3S,4S,5S)-5-{[(2R,3R,4R)-5-{4-[(6R,6aS,7S)-3-amino-6,7-dimethyl-1-oxo-1H,2H,5H,6H,6aH, ... 7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}-2,3,4-trihydroxypentyl]oxy}-3,4-dihydroxyoxolan-2-yl]methoxy …
Displaying drugs 8701 - 8725 of 11144 in total