Displaying drugs 851 - 875 of 1115 in total
PRTX-100
PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a subset of B-cells that are involved in the development and progression of various autoimmune diseases. These binding interactions enable the compound to modulate the function of these cells and restore the balance of the...
Investigational
Matched Synonyms: … Staphylococcus aureus protein A …
Matched Description: … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... These binding interactions enable the compound to modulate the function of these cells and restore the …
Matched Description: … PRTX-100 is a highly-purified form of Staphylococcal Protein A that binds directly to monocytes and a ... subset of B-cells that are involved in the development and progression of various autoimmune diseases ... These binding interactions enable the compound to modulate the function of these cells and restore the …
Recombinant stabilized RSV B prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup B stabilized prefusion F protein …
Matched Description: … expressed in Chinese hamster ovary cell lines and then purified and lyophilized. ... virus vaccine, adjuvanted] (Arexvy), Abrysvo is reconstituted with sterile water prior to injection and ... [L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and …
Matched Description: … expressed in Chinese hamster ovary cell lines and then purified and lyophilized. ... virus vaccine, adjuvanted] (Arexvy), Abrysvo is reconstituted with sterile water prior to injection and ... [L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Synonyms: … Anti-fap/interleukin-2 fusion protein ro6874281 …
Gontivimab
Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection).
Investigational
Matched Synonyms: … Anti-rsv protein f nanobody alx-0171 …
Matched Description: … Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult ... Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult ... Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Neisseria meningitidis serogroup b fhbp fusion protein antigen
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b fhbp fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b fhbp fusion protein antigen …
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl …
Matched Description: … routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding ... [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding ... [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), disulfide with human monoclonal CSL312 lambda-chain …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and ... Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and ... Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy …
Socazolimab
Socazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).
Investigational
Matched Synonyms: … death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), disulfide with human monoclonal zkab001 .lambda …
Poliomyelitis virus type 1 (live, attenuated)
Experimental
Matched Name: … Poliomyelitis virus type 1 (live, attenuated) …
Matched Mixtures name: … POLIO SABIN ONE AND THREE (ORAL) VACCINE …
Matched Mixtures name: … POLIO SABIN ONE AND THREE (ORAL) VACCINE …
Poliomyelitis virus type 3 (live, attenuated)
Experimental
Matched Name: … Poliomyelitis virus type 3 (live, attenuated) …
Matched Mixtures name: … POLIO SABIN ONE AND THREE (ORAL) VACCINE …
Matched Mixtures name: … POLIO SABIN ONE AND THREE (ORAL) VACCINE …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Bone morphogenetic protein 2 ... Bone morphogenetic protein 2 (human recombinant rhBMP-2) …
Matched Description: … and 131 amino acids. ... cells into osteoblasts, thus promoting bone and cartilage formation [A31952]. ... In 2004, it was approved by the FDA and is marketed as Infuse. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Proteins ... Bone Morphogenetic Proteins …
Matched Description: … and 131 amino acids. ... cells into osteoblasts, thus promoting bone and cartilage formation [A31952]. ... In 2004, it was approved by the FDA and is marketed as Infuse. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Proteins ... Bone Morphogenetic Proteins …
COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection
COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen Presentation Therapeutic Biologics (COVID-19--AP) (AP-TP-Bio)) .
Investigational
Matched Synonyms: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection ... COVID-19 Therapeutic Biologics - Spike-GM-CSF Protein Lactated Ringer's Injection …
Matched Name: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being …
Matched Name: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being …
Brazikumab
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
Matched Synonyms: … interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with human monoclonal medi2070 .lambda …
Matched Description: … Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study …
Matched Description: … Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study …
Respiratory syncytial virus vaccine, adjuvanted
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Matched Synonyms: … RECOMBINANT RESPIRATORY SYNCYTIAL VIRUS PRE-FUSION F PROTEIN ... RESPIRATORY SYNCYTIAL VIRUS PREFUSION F PROTEIN (RSVPREF3) …
Clemastine
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched Description: … ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and …
Matched Products: … Good Sense dayhist allergy …
Matched Products: … Good Sense dayhist allergy …
GALE-301
GALE-301 is an investigational cancer immunotherapy. It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune adjuvant, granulocyte macrophage-colony stimulating factor (GM-CSF).[A254696,L44166,L44171]
Investigational
Matched Synonyms: … Folate Binding Protein E39 vaccine …
Matched Description: … It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune …
Matched Description: … It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune …
SM-1997
SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, amino acids, peptides, nucleosides, and nucleotides. It is under investigation for the treatment of cutaneous sulfur mustard-induced injury.
Investigational
Matched Synonyms: … Solution of protein-free hemodialysate of calf blood …
Matched Description: … amino acids, peptides, nucleosides, and nucleotides. ... SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, …
Matched Description: … amino acids, peptides, nucleosides, and nucleotides. ... SM-1997 is a protein-free solution derived from calf's blood comprising electrolytes, trace minerals, …
GX-19 Vaccine
The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea . As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Investigational
Matched Synonyms: … DNA vaccine expressing SARS-CoV-2 S-protein antigen …
Matched Description: … for safety and efficacy[A219758,L16488]. ... As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels …
Matched Description: … for safety and efficacy[A219758,L16488]. ... As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels …
Human Recombinant Bone Morphogenetic Protein 4
Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Barecetamab
Investigational
Matched Synonyms: … factor receptor her3) (human monoclonal isu104 .gamma.1-chain), disulfide with human monoclonal isu104 .lambda …
Bizaxofusp
Investigational
Matched Synonyms: … Il4-pseudomonas exotoxin fusion protein mdna55 ... Il-4 pseudomonas toxin fusion protein (il-4(38-37)-pe38kdel) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
PAT-SM6
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Displaying drugs 851 - 875 of 1115 in total