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Displaying drugs 851 - 875 of 1298 in total
Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.
Investigational
Matched Synonyms: … HUMANIZED ANTI-HUMAN IL-13 MONOCLONAL ANTIBODY ... IMMUNOGLOBULIN G1(240-ALANINE, 241-ALANINE), ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MUS MUSCULUS MONOCLONAL ... RPC4046 .GAMMA.-1), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .KAPPA.-1, DIMER …
Matched Description: … Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Maytansine, n2-deacetyl-n2-(3-mercapto-1-oxopropyl)-, conjugated humanized c242 monoclonal antibody ... N2'-deacetyl-n2'-(3-mercapto-1-oxopropyl)-maytansine -conjugated humanized c242 monoclonal antibody ... Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Farletuzumab ecteribulin is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and Efficacy of Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types).
Investigational
Matched Synonyms: … Eribulin/farletuzumab antibody drug conjugate …
Matched Description: … is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and ... Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Recombinant human C1-INH ... Recombinant human C1 inhibitor ... Recombinant human C1-inhibitor …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... of several target proteases within these pathways including activated C1s, kallikrein, factor XIIa and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …
Matched Description: … aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a ... Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).
Investigational
Matched Synonyms: … immunoglobulin G1, anti-(human Claudin-18.2) (human-mus musculus monoclonal IMAB362 heavy chain), disulfide ... with human-mus musculus monoclonal IMAB362 .kappa. …
Matched Description: … Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational
Matched Synonyms: … Human Umbilical Cord Wharton’s Jelly-derived Mesenchymal Stem Cells …
Matched Name: … Human Umbilical Cord Mesenchymal Stem Cells …
Matched Description: … class II and its co-stimulatory ligands like CD40, CD80, and CD86. ... UC mesenchymal cells derived from Wharton’s jelly are the most studied and offer more stable and better ... osteogenic and adipogenic differentiation potentials. …
Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures in patients with disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment. Human...
Approved
Matched Name: … Human cord blood hematopoietic progenitor cell …
Matched Description: … lymphocytes, and granulocytes from human cord blood. ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen …
Investigational
Matched Name: … Allogeneic human pancreatic islets of Langerhans …
Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain ... ), disulfide with human-mus musculus monoclonal gsk3511294 .kappa. …
Matched Description: … Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab …
2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Investigational
Matched Synonyms: … Anti-TGF-beta antibody 2G7 ... Anti-TGF-beta monoclonal antibody 2G7 ... Anti-transforming growth factor-beta monoclonal antibody 2G7 …
Matched Description: … 2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech. …
Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Description: … and early 1970s. ... Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s …
Matched Salts name: … Terbutaline sulfate
Matched Products: … Terbutaline Sulfate ... TERBUTALINE SULFATE
Investigational
Matched Synonyms: … Ciliary neurotrophic factor, recombinant human
Matched Name: … Human ciliary neurotrophic factor, recombinant (E. coli) …
Investigational
Matched Synonyms: … HEMOPEXIN (HUMAN) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … RECOMBINANT HUMAN PLACENTAL GROWTH FACTOR …
Matched Name: … Recombinant human placental growth factor (PLGF-131) …
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY AK002 ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL ... Recombinant humanized, non-fucosylated IgG1 anti-Siglec-8 monoclonal antibody
Matched Categories: … Amino Acids, Peptides, and Proteins …
Amniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus.[A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine due to their potential for differentiation and multiplication.
Investigational
Matched Synonyms: … Human Amniotic Epithelial Cells …
Matched Description: … due to their potential for differentiation and multiplication. ... [A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine ... epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human
Investigational
Matched Synonyms: … Recombinant human biglycan …
CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen.
Investigational
Matched Synonyms: … fibrinogen-depleted human platelet lysate …
Matched Description: … CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen. …
Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).
Investigational
Matched Synonyms: … ), disulfide with human monoclonal js002 .kappa. ... apoptosis-regulated convertase 1, narc1, narc-1, proprotein convertase 9, pc9)), humanized monoclonal antibody ... Immunoglobulin g4, anti-(neural apoptosis-regulated convertase 1) (human monoclonal js002 .gamma.4-chain …
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma ... .4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa. …
Matched Description: … Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen …
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 ... .gamma.4-chain), disulfide with human-rattus norvegicus monoclonal ucb0107 .kappa. …
Matched Description: … Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau. …
Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Fibrinolysin is used as a...
Investigational
Matched Synonyms: … Fibrinolysin, human ... Fibrinolysin (human) …
Matched Description: … Fibrinolysin and deoxyribonuclease both act as lytic enzymes. ... Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. ... The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes ... fibrinolysin and desoxyribonuclease …
Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 851 - 875 of 1298 in total