Displaying drugs 8826 - 8850 of 8938 in total
Iopofosine I-131
Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).
Investigational
Matched Synonyms: … 2-((HYDROXY((18-(4-(131I)IODOPHENYL)OCTADECYL)OXY)PHOSPHINYL)OXY)-N,N,NTRIMETHYLETHANAMINIUM INNER SALT ... Ethanaminium, 2-((hydroxy((18-(4-(iodo-131I)phenyl)octadecyl)oxy)phosphinyl)oxy)-N,N,N-trimethyl-, inner …
Matched Iupac: … 18-[4-(¹³¹I)iodophenyl]octadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … 18-[4-(¹³¹I)iodophenyl]octadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Idursulfase beta
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Ginisortamab
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
L-proline betaine
Experimental
Matched Synonyms: … (S)-2-carboxylato-1,1-dimethylpyrrolidinium …
Matched Iupac: … (2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylate …
Matched Iupac: … (2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylate …
Aconiazide
Investigational
Matched Synonyms: … Isonicotinic acid (2-(carboxymethoxy)benzylidene)hydrazide …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid …
Matched Iupac: … 2-{2-[(E)-{[(pyridin-4-yl)formamido]imino}methyl]phenoxy}acetic acid …
Josamycin propionate
Experimental
Matched Iupac: … -2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate ... oxo-7-(2-oxoethyl)-10-(propanoyloxy)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy ... 6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-5-methoxy-9,16-dimethyl-2- …
Lutetium Lu177 Edotreotide
Investigational
Matched Iupac: … -2-yl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18 ... (177Lu)lutetium(3+) 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan ... -pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl …
C-1027 Aromatized chromophore
Experimental
Matched Iupac: … }-22-hydroxy-14-(7-methoxy-2-methylidene-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-5-carbonyloxy)-17-oxo-2,16 ... -dioxapentacyclo[18.2.2.1^{9,13}.0^{3,10}.0^{4,8}]pentacosa-1(22),5,7,9,11,13(25),20,23-octaen-19-aminium ... (3R,4R,14R,19S)-23-chloro-4-{[(2S,3R,4R,5S)-5-(dimethylamino)-3,4-dihydroxy-6,6-dimethyloxan-2-yl]oxy …
Alcuronium
A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Experimental
Matched Iupac: … }.0^{30,33}.0^{24,35}.0^{26,38}]octatriaconta-2(7),3,5,9,18(23),19,21,25-octaene-14,30-diium ... -2-en-1-yl)-8,14,24,30-tetraazaundecacyclo[25.5.2.2^{11,14}.1^{1,8}.1^{10,17}.0^{2,7}.0^{13,17}.0^{18,23 ... (1S,9Z,11S,13S,14R,17S,25Z,27S,28E,30R,33S,35S,37E,38S)-28,37-bis(2-hydroxyethylidene)-14,30-bis(prop …
Matched Salts cas: … 15180-03-7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 15180-03-7 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Regramostim
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ …
Matched Description: … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ …
Oxaloacetic acid
Investigational
Matched Synonyms: … 2-oxobutanedioic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Rhein
Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects.
Experimental
Matched Iupac: … 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid …
2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide
Experimental
Matched Name: … 2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide …
Matched Iupac: … 2-{4-[4-(4-chlorophenoxy)benzenesulfonyl]oxan-4-yl}-N-hydroxyacetamide …
Matched Iupac: … 2-{4-[4-(4-chlorophenoxy)benzenesulfonyl]oxan-4-yl}-N-hydroxyacetamide …
(1R)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid
Experimental
Matched Name: … (1R)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid …
Matched Iupac: … [(1R)-1-{4'-methoxy-[1,1'-biphenyl]-4-sulfonamido}-2-methylpropyl]phosphonic acid …
Matched Iupac: … [(1R)-1-{4'-methoxy-[1,1'-biphenyl]-4-sulfonamido}-2-methylpropyl]phosphonic acid …
N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID
Experimental
Matched Name: … N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID …
Matched Iupac: … (2R)-2-{benzyl[(R)-methyl(phenyl)phosphoryl]amino}-N-hydroxy-4-methylpentanamide …
Matched Iupac: … (2R)-2-{benzyl[(R)-methyl(phenyl)phosphoryl]amino}-N-hydroxy-4-methylpentanamide …
CIS-4-METHYL-N-[(1S)-3-(METHYLSULFANYL)-1-(PYRIDIN-4-YLCARBAMOYL)PROPYL]CYCLOHEXANECARBOXAMIDE
Experimental
Matched Name: … CIS-4-METHYL-N-[(1S)-3-(METHYLSULFANYL)-1-(PYRIDIN-4-YLCARBAMOYL)PROPYL]CYCLOHEXANECARBOXAMIDE …
Matched Iupac: … (2S)-4-(methylsulfanyl)-N-(pyridin-4-yl)-2-{[(1s,4s)-4-methylcyclohexyl]formamido}butanamide …
Matched Iupac: … (2S)-4-(methylsulfanyl)-N-(pyridin-4-yl)-2-{[(1s,4s)-4-methylcyclohexyl]formamido}butanamide …
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Albendazole oxide
Experimental
Matched Synonyms: … Methyl 5-(propylsulfinyl)-2-benzimidazolecarbamate …
Matched Iupac: … methyl N-[5-(propane-1-sulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … methyl N-[5-(propane-1-sulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
AMY-101
AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis).
Investigational
Matched Iupac: … ]-3-methylpentanamido]-7-(3-carbamimidamidopropyl)-4-{[(1S,2S)-1-carbamoyl-2-methylbutyl](methyl)carbamoyl ... 2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-34-[(2S,3S)-2-[(2R)-2-amino-3-(4-hydroxyphenyl)propanamido ... }-25-(2-carbamoylethyl)-10-[(1H-imidazol-5-yl)methyl]-19-[(1H-indol-3-yl)methyl]-13,17-dimethyl-28-[( ... 1-methyl-1H-indol-3-yl)methyl]-6,9,12,15,18,21,24,27,30,33-decaoxo-31-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32 …
Avalotcagene ontaparvovec
Investigational
Narasin
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Iupac: … -methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl ... ]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3,5-dimethyloxan-2-yl]butanoic acid ... (2R)-2-[(2R,3S,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6 …
4-acetamido-2,4-didexoy-D-glycero-beta-D-galacto-octopyranosylphosphonic acid
Experimental
Matched Iupac: … [(2S,4S,5R,6R)-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]phosphonic acid …
2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
Experimental
Matched Name: … 2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER …
Matched Iupac: … benzyl (2S)-2-[N'-(4-aminobutyl)hydrazinecarbonyl]pyrrolidine-1-carboxylate …
Matched Iupac: … benzyl (2S)-2-[N'-(4-aminobutyl)hydrazinecarbonyl]pyrrolidine-1-carboxylate …
4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
Experimental
Matched Name: … 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE …
Matched Iupac: … 4-[(5-benzenesulfonamido-1-methyl-1H-1,3-benzodiazol-2-yl)methyl]benzene-1-carboximidamide …
Matched Iupac: … 4-[(5-benzenesulfonamido-1-methyl-1H-1,3-benzodiazol-2-yl)methyl]benzene-1-carboximidamide …
(1S)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid
Experimental
Matched Name: … (1S)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid …
Matched Iupac: … [(1S)-1-{4'-methoxy-[1,1'-biphenyl]-4-sulfonamido}-2-methylpropyl]phosphonic acid …
Matched Iupac: … [(1S)-1-{4'-methoxy-[1,1'-biphenyl]-4-sulfonamido}-2-methylpropyl]phosphonic acid …
Displaying drugs 8826 - 8850 of 8938 in total