Displaying drugs 9126 - 9150 of 13048 in total
123I-iodometomidate
123I-iodometomidate is under investigation in clinical trial NCT00454103 (Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy).
Investigational
Matched Iupac: … methyl 1-[(1R)-1-(4-iodophenyl)ethyl]-1H-imidazole-5-carboxylate …
Rhenium Re-186 sulfide
Experimental
N-Carbamoylphenylalanine
Experimental
Matched Iupac: … (2S)-2-(carbamoylamino)-3-phenylpropanoic acid …
INO-4800
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … [A214475]
A Phase 1 clinical trial for INO-4800 in the U.S. ... [L14372] A Phase 1/2 clinical trial through South Korea's Seoul National University Hospital was announced ... (NCT04336410) was started on April 3, 2020, with an expected completion date of July 2021. …
3,4,5-Trimethoxyamphetamine
Experimental
Illicit
Matched Iupac: … 1-(3,4,5-trimethoxyphenyl)propan-2-amine …
AI-850
AI-850 is a Cremophor(R)-free formulation of paclitaxel, the active ingredient in Taxol(R), a product used to treat a variety of solid tumors.
Investigational
Matched Description: … AI-850 is a Cremophor(R)-free formulation of paclitaxel, the active ingredient in Taxol(R), a product ... used to treat a variety of solid tumors. …
AV-412
Investigational
Matched Iupac: … bis(4-methylbenzene-1-sulfonic acid); N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methylpiperazin ... -1-yl)but-1-yn-1-yl]quinazolin-6-yl}prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AC-430
AC430 has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … (4-fluorophenyl)({4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl})methanol …
Amber
Amber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Amber is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
AT-527
Investigational
Matched Iupac: … propan-2-yl (2S)-2-[({[(3R,4R,5R)-5-[2-amino-6-(methylamino)-9H-purin-9-yl]-4-fluoro-3-hydroxy-4-methyloxolan …
AL-034
AL-034 (TQ-A3334) is an oral toll-like receptor 7 agonist developed for the treatment of chronic hepatitis B (CHB) viral infection.
Investigational
Anti-SARS-CoV-2 immunoglobulin
Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. Anti-coronavirus immunoglobulin is derived from COVID-19 convalescent plasma(https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in convalescent plasma (https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.[L27521, L27526]
Investigational
Mavrilimumab
Mavrilimumab has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
AL-4623
Experimental
ABT-510
ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth. It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.
Investigational
Matched Iupac: … (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S,3S)-2-[(2S)-2-[(2S,3R)-3-hydroxy-2-[(2R,3S)-3-methyl ... ]-3-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide ... -2-[(2S)-3-methyl-2-{2-[2-(N-methylacetamido)acetamido]acetamido}butanamido]pentanamido]butanamido]pentanamido …
Matched Description: … ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and …
Matched Description: … ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and …
AGS-004
AGS-004 is a personalized RNA-loaded dendritic cellbased
immunotherapy that is designed to stimulate the patient’s immune system to target and destroy the patient’s own unique viral burden. Non-personalized HIV immunotherapies are unable to raise cytotoxic T lymphocytes against HIV antigens, fail to induce T cell memory, and, most importantly, do...
Investigational
Matched Description: … , providing a matched, complete immune response for each individual HIV patient. ... AGS-004 is a personalized RNA-loaded dendritic cellbased
immunotherapy that is designed to stimulate ... This approach may overcome the weaknesses of other available therapies and therefore could result in a …
ATX-201
ATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. It is developed by Kythera Biopharmaceuticals, Inc. for the treatment of actinic
keratosis. The company announced the decision to discontinue its ATX-201 clinical program for actinic keratosis. The Company determined that the program was not meeting their...
Investigational
Matched Description: … ATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. …
AIT-034
AIT-034 is a distinct chemical analog of hypoxanthine and pyrollidone that has been demonstrated in animal studies to enhance memory and to reverse memory deficits in severely impaired animals that do not respond to Neotrofin. AIT-034 does not induce the production of NGF, and its mechanism of action is therefore...
Investigational
Matched Iupac: … 3-(6-oxo-6,9-dihydro-3H-purin-9-yl)-N-[3-(2-oxopyrrolidin-1-yl)propyl]propanamide …
Matched Description: … AIT-034 is a distinct chemical analog of hypoxanthine and pyrollidone that has been demonstrated in animal ... There is some evidence that AIT-034 could complement Neotrofin as a treatment for Alzheimer's disease …
Matched Description: … AIT-034 is a distinct chemical analog of hypoxanthine and pyrollidone that has been demonstrated in animal ... There is some evidence that AIT-034 could complement Neotrofin as a treatment for Alzheimer's disease …
AS-8112
AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Experimental
Matched Iupac: … 5-bromo-N-[(6R)-1-ethyl-4-methyl-1,4-diazepan-6-yl]-2-methoxy-4-(methylamino)benzamide …
Matched Description: … AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AKN-028
AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
Displaying drugs 9126 - 9150 of 13048 in total