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Displaying drugs 9201 - 9225 of 11200 in total
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
Experimental
Matched Name: … 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone …
Matched Iupac: … 2-(1H-imidazol-1-yl)-1-[(3R,5S,7s)-adamantan-1-yl]ethan-1-one …
Matched Iupac: … 2-(1H-imidazol-1-yl)-1-[(3R,5S,7s)-adamantan-1-yl]ethan-1-one …
N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE
Experimental
Matched Name: … N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE …
Matched Iupac: … N-[2-(4-sulfamoylphenyl)ethyl]acetamide …
Matched Iupac: … N-[2-(4-sulfamoylphenyl)ethyl]acetamide …
Tesmilifene
Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Synonyms: … N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine …
Matched Iupac: … [2-(4-benzylphenoxy)ethyl]diethylamine …
Matched Iupac: … [2-(4-benzylphenoxy)ethyl]diethylamine …
Cobnabexagene anvuparvovec
Experimental
Mercaptoethanol
Experimental
Matched Synonyms: … 2-mercaptoethanol …
Matched Iupac: … 2-sulfanylethan-1-ol …
Matched Iupac: … 2-sulfanylethan-1-ol …
INM004
INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment ... Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …
Vilamakitug
Vilamakitug is under investigation in clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human Antibody Versus Trifluridine/tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine).
Investigational
Ifenprodil
N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Iupac: … 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol …
Matched Description: … Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 …
Matched Description: … Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 …
Modified vaccinia virus Ankara-85A antigen
Modified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants).
Investigational
N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate …
Matched Iupac: … 1-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopropane-1-carboxylic acid …
Matched Iupac: … 1-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopropane-1-carboxylic acid …
PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole
Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …
Matched Iupac: … [(5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic …
Matched Iupac: … [(5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic …
Barnidipine
Barnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in the vascular wall and selectivity against cardiovascular L-type calcium channels . Barnidipine...
Experimental
Matched Iupac: … 3-(3S)-1-benzylpyrrolidin-3-yl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … The active component is composed of a single optical isomer (*3'S, 4S* configuration), which is the most ... hypertension, the antihypertensive response from barnidipine treatment was maintained after a 1-year and 2- …
Matched Description: … The active component is composed of a single optical isomer (*3'S, 4S* configuration), which is the most ... hypertension, the antihypertensive response from barnidipine treatment was maintained after a 1-year and 2- …
Empegfilgrastim
Empegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Investigational
DCVAC/OvCa
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine
Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
1-[6-(2-CHLORO-4-METHYXYPHENOXY)-HEXYL]-IMIDAZOLE
Experimental
Matched Name: … 1-[6-(2-CHLORO-4-METHYXYPHENOXY)-HEXYL]-IMIDAZOLE …
Matched Iupac: … 1-[6-(2-chloro-4-methoxyphenoxy)hexyl]-1H-imidazole …
Matched Iupac: … 1-[6-(2-chloro-4-methoxyphenoxy)hexyl]-1H-imidazole …
Binodenoson
Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a...
Investigational
Matched Synonyms: … 2-((Cyclohexylmethylene)hydrazino)adenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-{6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazin-1-yl]-9H-purin-9-yl}-5-(hydroxymethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R,3R,4S,5R)-2-{6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazin-1-yl]-9H-purin-9-yl}-5-(hydroxymethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Immucin
Investigational
Leflutrozole
Leflutrozole is under investigation in clinical trial NCT02908074 (A 6 Month Safety Extension Study of MBGS205).
Investigational
WRR-112
Experimental
Matched Iupac: … (3S)-3-hydroxy-3-{[(1S)-1-[(3-methylbutyl)carbamoyl]-3-phenylpropyl]carbamoyl}propanoic acid …
1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine
1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. It is sold as a "synthetic heroin."
Experimental
Illicit
Matched Synonyms: … 1-(2-Phenethyl)-4-phenyl-4-acetoxypiperidine …
Matched Name: … 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine …
Matched Iupac: … 4-phenyl-1-(2-phenylethyl)piperidin-4-yl acetate …
Matched Description: … 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. …
Matched Name: … 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine …
Matched Iupac: … 4-phenyl-1-(2-phenylethyl)piperidin-4-yl acetate …
Matched Description: … 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. …
[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
Experimental
Matched Name: … [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid …
Matched Iupac: … [2-(N-hydroxyformamido)ethyl]phosphonic acid …
Matched Iupac: … [2-(N-hydroxyformamido)ethyl]phosphonic acid …
L-1-naphthyl-2-acetamido-ethane boronic acid
Experimental
Matched Name: … L-1-naphthyl-2-acetamido-ethane boronic acid …
Matched Iupac: … [(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]trihydroxyboranuide …
Matched Iupac: … [(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]trihydroxyboranuide …
D-1-naphthyl-2-acetamido-ethane boronic acid
Experimental
Matched Name: … D-1-naphthyl-2-acetamido-ethane boronic acid …
Matched Iupac: … trihydroxy[(1S)-1-[(1-hydroxyethylidene)amino]-2-(naphthalen-1-yl)ethyl]boranuide …
Matched Iupac: … trihydroxy[(1S)-1-[(1-hydroxyethylidene)amino]-2-(naphthalen-1-yl)ethyl]boranuide …
Displaying drugs 9201 - 9225 of 11200 in total