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Displaying drugs 9451 - 9475 of 10046 in total

Volixibat

Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH. Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Iupac: … yl]phenyl}carbamoyl)amino]-3,5-dihydroxyoxan-2-yl]methoxy}sulfonic acid ... ,5R)-3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1lambda6-benzothiepin-5- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole

Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …
Matched Iupac: … [(5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic …

1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester

Experimental

1,2-Dipalmitoyl-Phosphatidyl-Glycerole

Experimental

2-(Thiomethylene)-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-(Thiomethylene)-4-Methylpentanoic Acid …
Matched Iupac: … (2S)-4-methyl-2-(sulfanylmethyl)pentanoic acid …

4-Iodobenzo[B]Thiophene-2-Carboxamidine

Experimental
Matched Name: … 4-Iodobenzo[B]Thiophene-2-Carboxamidine …
Matched Iupac: … [amino(4-iodo-1-benzothiophen-2-yl)methylidene]azanium …

GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE

Experimental
Matched Name: … GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE …
Matched Iupac: … 3,4-d][1,3]dioxol-2-yl]phosphonic acid ... [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …

Zinpentraxin alfa

Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Synonyms: … rhPTX-2 ... Recombinant human pentraxin-2 …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. ... It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With …

Ontamalimab

Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational

4-(2-Aminoethyl)Benzenesulfonyl Fluoride

Experimental
Matched Name: … 4-(2-Aminoethyl)Benzenesulfonyl Fluoride …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonyl fluoride …

6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE

Experimental
Matched Name: … 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE …
Matched Iupac: … 6-hydroxy-1,3-benzothiazole-2-sulfonamide …

SP-876

Experimental
Matched Iupac: … (2S)-2-[(4-{[(2R)-2-[(2-carboxyethyl)carbamoyl]pyrrolidin-1-yl]sulfonyl}phenyl)formamido]pentanedioic …

Phenylethyl alcohol

An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
Experimental
Matched Synonyms: … 2-phenylethanol …
Matched Iupac: … 2-phenylethan-1-ol …

Propofol Hemisuccinate

Experimental
Matched Iupac: … 4-[2,6-bis(propan-2-yl)phenoxy]-4-oxobutanoic acid …

Plevitrexed

Investigational
Matched Iupac: … )formamido]-4-(1H-1,2,3,4-tetrazol-5-yl)butanoic acid ... (2S)-2-[(4-{[(2,7-dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}-2-fluorophenyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tezosentan

Tezosentan is an intravenous endothelin receptor A/B antagonist. Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.
Investigational
Matched Iupac: … N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl ... ]-5-(propan-2-yl)pyridine-2-sulfonamide …

Zilurgisertib

Investigational
Matched Iupac: … 2-amino-N-{4-hydroxybicyclo[2.2.2]octan-1-yl}-5-{4-[(1R,5S)-3-(oxan-4-yl)-3-azabicyclo[3.1.0]hexan-1- …

3-(4-carbamoyl-1-carboxy-2-methylsulfonyl-buta-1,3-dienylamino)-indolizine-2-carboxylic acid

Experimental
Matched Name: … 3-(4-carbamoyl-1-carboxy-2-methylsulfonyl-buta-1,3-dienylamino)-indolizine-2-carboxylic acid …
Matched Iupac: … (2Z)-2-[(2-formylindolizin-3-yl)amino]-5-(C-hydroxycarbonimidoyl)-3-(sulfonylmethyl)penta-2,4-dienoic …

RU90395

Experimental
Matched Iupac: … 2-{4-[(2S)-2-{[(3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2- ... (methoxycarbonyl)phenyl}-2-fluoropropanedioic acid …

6-hydroxy-FAD

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3S,4S)-2,3,4 ... -trihydroxy-5-{6-hydroxy-7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}pentyl]oxy})phosphoryl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

GDP-alpha-D-mannuronic acid

Experimental
Matched Iupac: … (2S,3S,4S,5S,6R)-6-({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid …

Cpad

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4R,5S)-5-(6-carbamoylpyridin ... -2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphinic acid …

Histidyl-Adenosine Monophosphate

Experimental
Matched Iupac: … {[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]oxy}({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan ... -2-yl]methoxy})phosphinic acid …

Adenylosuccinic acid

Experimental
Matched Iupac: … (2S)-2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Vapreotide

Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Experimental
Investigational
Matched Iupac: … (2R)-2-amino-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl ... ]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2- …
Displaying drugs 9451 - 9475 of 10046 in total