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Displaying drugs 926 - 950 of 1092 in total
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Investigational
Matched Synonyms: … Anti-CEA sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201) …
Investigational
Matched Synonyms: … Human major histocompatibility complex (MHC) non-restricted T-cell line 104 …
Investigational
Matched Synonyms: … Recombinant human cerebral dopamine neurotrophic factor …
MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).
Investigational
Matched Synonyms: … Two immunoglobulin subclass 1 (IgG1) human monoclonal antibodies that target the Sudan ebolavirus glycoprotein …
Matched Description: … MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. …
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …
Matched Description: … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Nerve Tissue Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues …
Somatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.
Investigational
Matched Synonyms: … SOMATOLIBERIN, HUMAN ... SOMATOLIBERIN (HUMAN) ... GROWTH HORMONE-RELEASING FACTOR (HUMAN) …
Matched Description: … been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins
Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1(240-ALANINE, 241-ALANINE), ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MUS MUSCULUS MONOCLONAL ... HUMANIZED ANTI-HUMAN IL-13 MONOCLONAL ANTIBODY ... RPC4046 .GAMMA.-1), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .KAPPA.-1, DIMER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse ... Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulphide with human-mouse ... Immunoglobulin g1, anti-(mucin canag) human-mouse monoclonal c242 heavy chain), disulfide with human-mouse …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
Investigational
Matched Synonyms: … PLUS HUMAN MINI-DYSTROPHIN GENE PLUS ADENO-ASSOCIATED VIRUS 9 INVERTED TERMINAL REPEAT FLANKS) ... DNA (RECOMBINANT ADENO-ASSOCIATED VIRUS 9 VECTOR PF-06939926 HUMAN MUSCLE-SPECIFIC ENHANCER/PROMOTER …
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 2g11 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma …
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 1a9 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma …
Investigational
Matched Synonyms: … DNA (synthetic vaccinia virus strain MVA human papillomavirus-targeted) …
Investigational
Matched Synonyms: … Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Investigational
Matched Synonyms: … Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 …
Matched Description: … intention to be used for the treatment of calcification disorders of the circulatory system, bones, and
PRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Investigational
Matched Synonyms: … Modified messenger ribonucleic acid encoding human argininosuccinate lyase enzyme encapsulated into lipid …
Investigational
Matched Synonyms: … Recombinant human fibroblast growth factor receptor 3 ... Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46) ... Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble …
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Synonyms: … Human brain natriuretic factor-32 …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins
AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.
Investigational
Matched Synonyms: … Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfatase …
Matched Description: … investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and ... a human insulin receptor monoclonal antibody. …
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … is grown in yeast and then isolated, the human form is isolated from pooled human plasma. ... As a result, the active transglutaminase from subunit A cross-links fibrin and other proteins resulting ... and maintenance of hemostasis [A18581]. …
Matched Categories: … Blood and Blood Forming Organs …
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … paclitaxel protein-bound particles ... Paclitaxel protein-bound particles for injection suspension …
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar ... Proteins
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …
Approved
Matched Synonyms: … Haemophilus influenzae type b polysaccharide conjugated to tetanus protein ... Haemophilus influenzae type b polysaccharide conjugated to the tetanus protein
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 27) (human monoclonal SRF388 γ1-chain), disulfide with human
Displaying drugs 926 - 950 of 1092 in total