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Displaying drugs 9551 - 9575 of 10915 in total

Posizolid

Posizolid (AZD2563) is an oxazolidinone antibiotic. In July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were no longer pursuing the development of Posizolid, presumably due to negative trial results (though no results were reported).
Investigational
Matched Iupac: … -oxazol-3-yloxy)methyl]-1,3-oxazolidin-2-one ... (5R)-3-(4-{1-[(2S)-2,3-dihydroxypropanoyl]-1,2,3,6-tetrahydropyridin-4-yl}-3,5-difluorophenyl)-5-[(1,2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

MK-0557

MK0557 has been investigated for the treatment of Schizophrenia and Paranoid Schizophrenia.
Investigational
Matched Iupac: … (1r,4r)-N-[1-(2-fluorophenyl)-1H-pyrazol-3-yl]-1'-oxo-1'H-spiro[cyclohexane-1,3'-furo[3,4-c]pyridine] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bacteriochlorophyll A

A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.
Experimental
Matched Iupac: … [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),13,15,17,19-nonaene-7,24 ... -22-(3-oxo-3-{[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo ... magnesium(2+) (3R,11R,12R,21S,22S)-16-acetyl-11-ethyl-3-(methoxycarbonyl)-12,17,21,26-tetramethyl-4-oxo …

Arketamine

Arketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Investigational
Matched Synonyms: … Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (2r)- ... Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+)- …

Dichlorvos

Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved

N-Alkyl dimethyl benzyl ammonium chloride (C12-C18)

Experimental

Evans blue

Investigational
Matched Iupac: … tetrasodium 8-amino-2-[(E)-2-{4'-[(E)-2-(8-amino-1-oxido-7-sulfo-5-sulfonatonaphthalen-2-yl)diazen-1- ... yl]-3,3'-dimethyl-[1,1'-biphenyl]-4-yl}diazen-1-yl]-7-sulfo-5-sulfonatonaphthalen-1-olate …

Guanosine-2'-monophosphate

Experimental
Matched Synonyms: … 2'-GMP ... 2'-guanylic acid ... 2'-O-phosphoguanosine …
Matched Name: … Guanosine-2'-monophosphate …
Matched Iupac: … {[(2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM

Experimental
Matched Iupac: … [2-(dodecyldimethylphosphaniumyl)-1-phosphonoethyl]phosphonic acid …

2-Hydroxy-Tryptophan

Experimental
Matched Name: … 2-Hydroxy-Tryptophan …
Matched Iupac: … (2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid …

2-Bromohypoxanthine

Experimental
Matched Name: … 2-Bromohypoxanthine …
Matched Iupac: … 2-bromo-6,7-dihydro-1H-purin-6-one …

2-(aminomethyl)phenol

2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study in Older Adults).
Investigational
Matched Synonyms: … 2-HOBA …
Matched Name: … 2-(aminomethyl)phenol …
Matched Iupac: … 2-(aminomethyl)phenol …
Matched Description: … 2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study …

D-Proline

D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva . These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity .
Experimental
Matched Synonyms: … (R)-2-Carboxypyrrolidine ... (2R)-pyrrolidine-2-carboxylic acid ... (R)-pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R)-pyrrolidine-2-carboxylic acid …

Surinabant

Surinabant has been investigated for the treatment of Smoking Cessation.
Investigational
Matched Iupac: … 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-Methylbutanoic Acid

Experimental
Matched Name: … 2-Methylbutanoic Acid …
Matched Iupac: … (2R)-2-methylbutanoic acid …

Heptulose-2-Phosphate

Experimental
Matched Name: … Heptulose-2-Phosphate …
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-methyloxan-2-yl]oxy}phosphonic acid …

SARS-CoV-2 mRNA vaccine

SARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2 . It is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd....
Investigational
Matched Name: … SARS-CoV-2 mRNA vaccine …
Matched Description: … Manufactured as a liquid, ARCoV is thermostable at room temperature for at least 1 week. ... mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. ... As of July 2020, the vaccine candidate is set for Phase 1 clinical trials to investigate for safety, …

2'-deoxythioguanosine

Investigational
Matched Synonyms: … 2-amino-9-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-6-mercaptopurine ... 2'-deoxy-6-thioguanosine ... 2'-desoxy-6-thioguanosine …
Matched Name: … 2'-deoxythioguanosine …
Matched Iupac: … 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purine-6-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

G17DT Immunogen

G17DT Immunogen is a vaccine that neutralizes gastrin-17, a hormone required for the growth of a number of cancers of the gastrointestinal tract. It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine. It is also in a phase II/III trial for...
Investigational
Matched Description: … It is also in a phase II/III trial for advanced stomach cancer in combination with 5-fluorouracil and …

6-bromopurine

Experimental

Interleukin-15, human recombinant

Investigational

Ravuconazole

Investigational
Matched Iupac: … 4-{2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

MRX-I

MRX-I has been used in trials studying the treatment of Bacterial Infections.
Investigational
Matched Iupac: … 1-{2,3,6-trifluoro-4-[(5S)-5-{[(1,2-oxazol-3-yl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl]phenyl}-1,2,3,4 …

Lisavanbulin

Lisavanbulin is under investigation in clinical trial NCT02895360 (Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma).
Investigational
Matched Iupac: … (2S)-2,6-diamino-N-{4-[2-(2-{4-[(2-cyanoethyl)amino]-1,2,5-oxadiazol-3-yl}-1H-1,3-benzodiazol-1-yl)acetyl …
Matched Description: … Lisavanbulin is under investigation in clinical trial NCT02895360 (Phase 1/2a Study of BAL101553 as 48 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Razuprotafib

Razuprotafib, also known as AKB-9778, is a small-molecule inhibitor restoring Tie2 activation by inhibiting VE-PTP.[L27171,L27176] In investigations against diabetes and COVID-19, razuprotafib is self-administered by patients through subcutaneous injection.
Investigational
Matched Iupac: … N-{4-[(2S)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-phenylpropanamido]-2-[2-(thiophen-2-yl)-1,3-thiazol-4 …
Displaying drugs 9551 - 9575 of 10915 in total