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Displaying drugs 9851 - 9875 of 10789 in total
Ramosetron
Ramosetron is a serotonin 5-HT3 receptor antagonist commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Currently, ramosetron is only approved for use Japan and in...
Investigational
Matched Iupac: … (5R)-5-(1-methyl-1H-indole-3-carbonyl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole …
Roquinimex
Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
Investigational
Matched Iupac: … 4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide …
Gefarnate
Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease.
Investigational
Matched Iupac: … (2E)-3,7-dimethylocta-2,6-dien-1-yl (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate …
Raclopride
Raclopride has been used in trials studying Parkinson Disease.
Investigational
Matched Iupac: … 3,5-dichloro-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-hydroxy-6-methoxybenzamide …
Icosabutate
Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study).
Investigational
Matched Iupac: … 2-[(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaen-1-yloxy]butanoic acid …
Enecadin
Enecadin has been investigated for the treatment of Stroke.
Investigational
Matched Iupac: … 4-(4-fluorophenyl)-2-methyl-6-{[5-(piperidin-1-yl)pentyl]oxy}pyrimidine …
Idanpramine
Experimental
Matched Iupac: … 5,5-bis(4-methoxyphenyl)-3-[2-(piperidin-1-yl)ethyl]imidazolidine-2,4-dione …
Flufenoxuron
Flufenoxuron is under investigation in clinical trial NCT00922870 (Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock).
Investigational
Matched Iupac: … 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}-3-(2,6-difluorobenzoyl)urea …
AN2898
AN2898 is under investigation in clinical trial NCT01301508 (Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-moderate Atopic Dermatitis).
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzene-1,2-dicarbonitrile …
Benzethidine
Experimental
Illicit
Matched Iupac: … ethyl 1-[2-(benzyloxy)ethyl]-4-phenylpiperidine-4-carboxylate …
(2s,4s)-Alpha-Campholinic Acid
Experimental
Matched Iupac: … (2S,4R)-4-(2,2-dihydroxyethyl)-2,3,3-trimethylcyclopentan-1-one …
[(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
Experimental
Matched Iupac: … (9Z)-octadec-9-en-1-yl (2R)-2,3-dihydroxypropanoate …
Clobutinol
Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.
Withdrawn
Matched Iupac: … 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol …
Alaproclate
Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal studies. Alaproclate has also been found to act as a non-competitive NMDA receptor antagonist although without discriminative...
Experimental
Matched Iupac: … 1-(4-chlorophenyl)-2-methylpropan-2-yl 2-aminopropanoate …
HSK-3486
HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation).
Investigational
Matched Iupac: … 2-[(1R)-1-cyclopropylethyl]-6-(propan-2-yl)phenol …
Drostanolone
Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone. Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy.
Illicit
Matched Iupac: … (1S,3aS,3bR,5aS,8R,9aS,9bS,11aS)-1-hydroxy-8,9a,11a-trimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …
MMDA
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Iupac: … 1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine …
Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine
Experimental
Matched Iupac: … (2S)-2-(2-aminoacetamido)-6-{[(1R)-1-carboxyethyl]carbamoyl}hexanoic acid …
Octylphenoxy polyethoxyethanol
Experimental
Matched Iupac: … 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87-nonacosaoxanonaoctacontan-1- …
Sivifene
Investigational
Matched Iupac: … 4-{[2-(2,4-dinitrophenyl)hydrazin-1-ylidene](4-hydroxyphenyl)methyl}phenol …
Methyl red
Experimental
Matched Iupac: … 2-[(1E)-2-[4-(dimethylamino)phenyl]diazen-1-yl]benzoic acid …
Displaying drugs 9851 - 9875 of 10789 in total