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Displaying drugs 9901 - 9925 of 10825 in total

Hetrombopag

Hetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).
Investigational
Matched Iupac: … 5-(2-hydroxy-3-{2-[(4Z)-3-methyl-5-oxo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)-4,5-dihydro-1H-pyrazol-4 ... -ylidene]hydrazin-1-yl}phenyl)furan-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Gitoformate

Experimental
Matched Iupac: … oxo-2,5-dihydrofuran-3-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl formate ... (1S,2S,5S,7R,10R,11S,13S,14R,15R)-5-{[(2R,4S,5R,6R)-5-{[(2S,4S,5R,6R)-5-{[(2S,4S,5R,6R)-4,5-bis(formyloxy ... formyloxy)-6-methyloxan-2-yl]oxy}-4-(formyloxy)-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyl-14-(5- …

Solasonine

Investigational
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R ... ,16S)-5',7,9,13-tetramethyl-5-oxaspiro[pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-piperidin ... ]-18-eneoxy]-5-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-4-yl]oxy}-6-(hydroxymethyl …

6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE

Experimental
Matched Name: … 6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE …
Matched Iupac: … 6-carbamimidoyl-N-[3-(cyclopentyloxy)phenyl]naphthalene-2-carboxamide …

[N-(3-dibenzylcarbamoyl-oxiranecarbonyl)-hydrazino]-acetic acid

Experimental
Matched Name: … [N-(3-dibenzylcarbamoyl-oxiranecarbonyl)-hydrazino]-acetic acid …
Matched Iupac: … 2-[N-amino-3-(dibenzylcarbamoyl)-3-hydroxypropanamido]acetic acid …

3-{(R)-(Dihydroxyboryl)[(2-thienylacetyl)amino]methyl}benzoic acid

Experimental
Matched Name: … 3-{(R)-(Dihydroxyboryl)[(2-thienylacetyl)amino]methyl}benzoic acid …
Matched Iupac: … 3-[(R)-(dihydroxyboranyl)[2-(thiophen-2-yl)acetamido]methyl]benzoic acid …

4-Methylthio-Alpha-D-Mannose

Experimental
Matched Iupac: … (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-(methylsulfanyl)oxane-2,3,4-triol …

Trapidil

Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Iupac: … N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lisofylline

Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Investigational
Matched Iupac: … 1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus. …

AKN-028

AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
Matched Iupac: … N2-(1H-indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine …

Ripasudil

Ripasudil, as hydrochloride hydrate (K-115), is a specifc Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor used for the treatment of glaucoma and ocular hypertension. It was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the...
Experimental
Matched Iupac: … 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …

SAR-405838

SAR405838 has been used in trials studying the treatment of Neoplasm Malignant.
Investigational
Matched Iupac: … (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-N-[(1r,4r)-4-hydroxycyclohexyl ... ]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide …

Pelacarsen

Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Investigational

Isoquercitrin

Isoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19).
Investigational
Matched Synonyms: … Quercetin 3-(beta-D-glucofuranoside) …
Matched Iupac: … 3-{[(2S,3R,4R,5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy}-2-(3,4-dihydroxyphenyl)-5,7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tiprelestat

Investigational
Matched Synonyms: … Elastase-specific inhibitor, skin-derived antileukoproteinase, peptidase inhibitor 3 …

alpha,beta-Dehydroaminobutyric acid

Experimental

Terameprocol

Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
Investigational
Matched Iupac: … 4-[(2R,3S)-3-[(3,4-dimethoxyphenyl)methyl]-2-methylbutyl]-1,2-dimethoxybenzene …

S-[(2E)-3,7-DIMETHYLOCTA-2,6-DIENYL] TRIHYDROGENTHIODIPHOSPHATE

Experimental
Matched Iupac: … [({[(2E)-3,7-dimethylocta-2,6-dien-1-yl]sulfanyl}(hydroxy)phosphoryl)oxy]phosphonic acid …

PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE]

Experimental
Matched Name: … PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] …
Matched Iupac: … N4,N6-bis[(pyridin-3-yl)methyl]pyrimidine-4,6-dicarboxamide …

3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate

Experimental
Matched Name: … 3-{[(4-methylphenyl)sulfonyl]amino}propyl pyridin-4-ylcarbamate …
Matched Iupac: … 3-(4-methylbenzenesulfonamido)propyl N-(pyridin-4-yl)carbamate …

3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE

Experimental
Matched Name: … 3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE …
Matched Iupac: … 3-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …

Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone

Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial NCT02688101 (Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced Solid Tumors).
Investigational
Matched Name: … Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone …
Matched Iupac: … 1-{[bis(pyridin-2-yl)methylidene]amino}-3-cyclohexyl-3-methylthiourea …
Matched Description: … Di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone is under investigation in clinical trial …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Hycanthone

Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Experimental
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one ... 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Zalifrelimab

Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Description: … Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently …

Onfekafusp alfa

Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Displaying drugs 9901 - 9925 of 10825 in total