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Displaying drugs 76 - 100 of 213 in total
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Mixtures name: … SPF 30 With Titanium Dioxide ... Avobenzone, Octinoxate, Titanium Dioxide ... Avobenzone, Octinoxate, Titanium Dioxide …
Experimental
Matched Synonyms: … Titanium element ... Titanium metallicum …
Matched Name: … Titanium
Matched Iupac: … titanium
Experimental
Matched Synonyms: … Thiamine disulfide ... Vitamin B1 disulfide
Matched Name: … Thiamine disulfide
Experimental
Matched Name: … Glutathionylspermidine disulfide
Experimental
Matched Name: … 2-Hydroxyethyl Disulfide
Experimental
Matched Name: … 4,4'-DIPYRIDYL DISULFIDE
PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment...
Investigational
Matched Synonyms: … 1-Methylpropyl-2-imidazolyl disulfide
Matched Description: … PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), …
Alethine is studied in the treatment of cancer. It belongs to a family of chemicals called disulfides. It is a low molecular weight disulfide that has been shown to exhibit in vivo antitumor activity in murine myeloma and melanoma models.
Investigational
Matched Synonyms: … Beta-alanyl cysteamine disulfide
Matched Description: … It is a low molecular weight disulfide that has been shown to exhibit in vivo antitumor activity in murine …
Experimental
Matched Synonyms: … N'-Glutathionylspermidine disulfide
Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).
Investigational
Matched Synonyms: … D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2 (disulfide bridge: 2-6) …
Matched Salts name: … D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2 (disulfide bridge: 2-6) acetate …
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa. ... Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma …
Investigational
Matched Synonyms: … Disulfide, 2-propenyl 3-(2-propenylsulfinyl)-1-propenyl ... 2-propen-1-yl (3-(2-propen-1-ylsulfinyl)-1-propen-1-yl) disulfide
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Synonyms: … with human clone 0365-0001-9985 κ-chain, (228.fwdarw.226′),(231.fwdarw.229′)-bis(disulfide) with anti ... proline,de-449-lysine], anti-(human blood-coagulation factor IX) (human clone 0365-0001-9985 γ4-chain), disulfide
Investigational
Matched Synonyms: … -chain), disulfide with mouse monoclonal xmmen-0e5 light chain, pentameric dimer ... Immunoglobulin m (mouse monoclonal xmmen-0e5 anti-endotoxin), disulfide with mouse monoclonal xmmen-0e5 ... Immunoglobulin m (mouse monoclonal xmmen-oe5 anti-endotoxin), disulfide with mouse monoclonal xmmen-oe5 …
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(human blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), disulfide
Investigational
Matched Synonyms: … ANTI (STAPHYLOCOCCUS EPIDERMIDIS LIPOTEICHOIC ACID) (HUMAN MOUSE MONOCLONAL HU96 110 HEAVY CHAIN), DISULFIDE ... Immunoglobulin G1, anti-(Staphylococcus epidermidis lipoteichoic acid) (human-mouse monoclonal heavy chain), disulfide ... IMMUNOGLOBULIN G1, ANTI-(STAPHYLOCOCCUS EPIDERMIDIS LIPOTEICHOIC ACID)(HUMAN-MOUSE MONOCLONAL HEAVY CHAIN), DISULFIDE
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human epidermal growth factor receptor her3) (human monoclonal isu104 .gamma.1-chain), disulfide
Investigational
Matched Synonyms: … Immunoglobulin igg4, anti-(human cd47) (human monoclonal srf231 .gamma.4-chain), disulfide with human …
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with …
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Synonyms: … l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN-MUS MUSCULUS MONOCLONAL TST001 .GAMMA.1-CHAIN), DISULFIDE
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain), disulfide
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN …
Investigational
Matched Synonyms: … (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a …
Displaying drugs 76 - 100 of 213 in total