Displaying drugs 10151 - 10175 of 11105 in total
Vercirnon
Vercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is under investigation in clinical trial NCT01611805 (Japanese Phase I of GSK1605786).
Investigational
Matched Iupac: … 4-[2-(4-tert-butylbenzenesulfonamido)-5-chlorobenzoyl]pyridin-1-ium-1-olate …
Chromium histidinate
Investigational
Matched Iupac: … chromium(3+) tris((2S)-2-amino-3-(1H-imidazol-5-yl)propanoate) …
6-hydroxynorleucine
Experimental
Matched Synonyms: … 2-Amino-6-hydroxycaproic acid …
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid …
Matched Iupac: … (2S)-2-amino-6-hydroxyhexanoic acid …
Glutathionylspermidine
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-{[({3-[(4-aminobutyl)amino]propyl}-C-hydroxycarbonimidoyl)methyl]-C-hydroxycarbonimidoyl ... }-2-sulfanylethyl]-C-hydroxycarbonimidoyl}butanoic acid …
Phloretic acid
Experimental
Matched Synonyms: … 3-(4-Hydroxyphenyl)propionic acid ... 3-(p-hydroxyphenyl)propionic acid …
Matched Iupac: … 3-(4-hydroxyphenyl)propanoic acid …
Matched Iupac: … 3-(4-hydroxyphenyl)propanoic acid …
Bilh 434
Experimental
Matched Iupac: … (2R,3'R,4'S,5'R)-5'-(3,4-dichlorophenyl)-6-methyl-1,3-dioxo-4'-{[4-(1,2,3-thiadiazol-4-yl)phenyl]carbamoyl ... }-1,3-dihydrospiro[indene-2,2'-oxolane]-3'-carboxylic acid …
Tacalcitol
Experimental
Investigational
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden …
L-N(omega)-Nitroarginine-2,4-L-diaminobutyric amide
Experimental
Matched Iupac: … (2S)-2-amino-N-[(1S)-3-amino-1-carbamoylpropyl]-5-(N'-nitrocarbamimidamido)pentanamide …
N-[(6-butoxynaphthalen-2-yl)sulfonyl]-D-glutamic acid
Experimental
Matched Name: … N-[(6-butoxynaphthalen-2-yl)sulfonyl]-D-glutamic acid …
Matched Iupac: … (2R)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Matched Iupac: … (2R)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Acecainide
Acecainide is an investigational anti-arrhythmia drug.
Investigational
Matched Synonyms: … 4'-((2-(diethylamino)ethyl)carbamoyl)acetanilide ... Benzamide, 4-(acetylamino)-n-(2-(diethylamino)ethyl)- …
Matched Iupac: … N-[2-(diethylamino)ethyl]-4-acetamidobenzamide …
Matched Iupac: … N-[2-(diethylamino)ethyl]-4-acetamidobenzamide …
Tolrestat
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was sold under the tradename...
Withdrawn
Matched Iupac: … 2-{1-[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-N-methylmethanethioamido}acetic acid …
7-Deaza-7-Aminomethyl-Guanine
Experimental
Matched Iupac: … 2-amino-5-(aminomethyl)-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one …
Coelenteramide
Experimental
Matched Iupac: … N-[3-benzyl-5-(4-hydroxyphenyl)pyrazin-2-yl]-2-(4-hydroxyphenyl)acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK-0354
MK-0354, is an orally administered drug candidate under development by Merck for the treatment of atherosclerosis and related disorders. It targets G protein-coupled receptor, or GPCR, that have the potential to regulate plasma lipid profiles, including HDL, or the good cholesterol, similar to the therapeutic action of niacin.
Investigational
Matched Iupac: … 5-{1H,4H,5H,6H-cyclopenta[c]pyrazol-3-yl}-2H-1,2,3,4-tetrazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dextofisopam
Investigational
Matched Iupac: … (5R)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Losmapimod
Losmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Azemiglitazone
Azemiglitazone is under investigation in clinical trial NCT01280695 (A Randomized, Double-blind, Comparator- and Placebo-controlled, Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in Type 2 Diabetic Patients).
Investigational
Matched Iupac: … 5-({4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in Type 2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in Type 2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Metadoxine
Experimental
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Aclarubicin
Investigational
Matched Iupac: … )-6-methyl-5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2-ethyl-2,5,7-trihydroxy-6,11-dioxo ... -1,2,3,4,6,11-hexahydrotetracene-1-carboxylate ... methyl (1R,2R,4S)-4-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2S,4S,5S,6S)-4-hydroxy-6-methyl-5-{[(2R,6S …
Matched Salts cas: … 75443-99-1 …
Matched Salts cas: … 75443-99-1 …
Emetonium iodide
Experimental
Matched Synonyms: … (2-benzhydryloxyethyl)diethyl-methylammonium iodide …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]diethylmethylazanium iodide …
Matched Categories: … (2-benzhydryloxyethyl)diethyl-methylammonium iodide …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]diethylmethylazanium iodide …
Matched Categories: … (2-benzhydryloxyethyl)diethyl-methylammonium iodide …
Temelimab
Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Spanlecortemlocel
Investigational
4-(2-HYDROXYPHENYLSULFINYL)-BUTYLPHOSPHONIC ACID
Experimental
Matched Name: … 4-(2-HYDROXYPHENYLSULFINYL)-BUTYLPHOSPHONIC ACID …
Matched Iupac: … {4-[(R)-2-hydroxybenzenesulfinyl]butyl}phosphonic acid …
Matched Iupac: … {4-[(R)-2-hydroxybenzenesulfinyl]butyl}phosphonic acid …
Displaying drugs 10151 - 10175 of 11105 in total