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Displaying drugs 1001 - 1025 of 1390 in total

Human umbilical cord blood mononuclear cell-conditioned medium

Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines these cells secrete are also implicated. When HUCBCs secrete growth factors and anti-inflammatory cytokines, they are...
Investigational
Matched Name: … Human umbilical cord blood mononuclear cell-conditioned medium …
Matched Description: … and associated damage. ... and cultured in Dulbecco’s modified Eagle’s medium. ... Then, the medium is filtered and separated from the HUCBCs. …

Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and ... mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... metoprolol and felodipine ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers …
Matched Products: … FELODIPIN 1A PHARMA 5MG ... FELODIPIN 1A PHARMA 10MG …

Elranatamab

Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS ... IMMUNOGLOBULIN G2 (224-ARGININE,265-ALANINE,330-SERINE,331-SERINE), ANTI-(HUMAN CD3 ANTIGEN .EPSILON. ... T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN)), HUMAN-MUS …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Amoxicillin

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … AMOXICLAV 500/125 1A PHARM ... AMOXICLAV 500/125 1A PHARM ... AMOXICLAV 875/125 1A PHARM …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... omeprazole, amoxicillin and rifabutin ... vonoprazan, amoxicillin and clarithromycin ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … AMOXI 500 1A PHARMA ... AMOXI 750 1A PHARMA ... AMOXI 1000 1A PHARMA …

Brinzolamide

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Description: … ], the first-ever approved topical CA inhibitor with contrasting results and evidence. ... pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and ... [A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … BRINZOLAMID 1A PHAR10MG/ML …

Palifermin

Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

OptPA

Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational
Matched Synonyms: … Pptimized human tissue-type plasminogen activator …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil …
Matched Products: … VERAPAMIL 120 1A PHARMA ... VERAPAMIL 120 RET 1A PHARM ... VERAPAMIL 40 1A PHARMA …

Clopidogrel

Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL 1A PHARMA ... Clopidogrel 1a Pharma ... Clopido Grel 1a Pharma …

Tarcocimab tedromer

Tarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)).
Investigational
Matched Synonyms: … growth factor A) (human-Mus musculus monoclonal OG1950 g1-chain), disulfide with human-Mus musculus ... Immunoglobulin G1 [240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial …
Matched Description: … Tarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and …

MDX-1303

MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins known as the anthrax protective antigen.
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN MONOCLONAL 5E8 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN, ANTI-(BACILLUS ANTHRACIS ANTHRAX PROTECTIVE ANTIGEN) (HUMAN MONOCLONAL 5E8 HEAVY CHAIN …
Matched Description: … humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins ... MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in …

Ozanezumab

Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Synonyms: … HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH …
Matched Description: … has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

NBL-015

Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …
Matched Products: … VIAGRA 50MG AĞIZDA DAĞILAN TABLET, 12 TABLET ... SILDE 1A PHARMA PAH 20MG ... Silde – 1A Pharma 100 mg Tabletten …

Fludeoxyglucose (18F)

Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Categories: … Indicators and Reagents …
Matched Products: … STERIFDG 250 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 12 DOZ …

Bicalutamide

Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.
Approved
Matched Description: … It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide …
Matched Categories: … Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... leuprorelin and bicalutamide ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BICALUTAMID 1A PHARMA50MG ... BICALUTAMID 1A PHARMA 50 ... BICALUTAMID 1A PHARM 150MG …

Triflupromazine

A phenothiazine used as an antipsychotic agent and as an antiemetic.
Approved
Vet approved
Matched Synonyms: … 2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine …
Matched Description: … A phenothiazine used as an antipsychotic agent and as an antiemetic. …
Matched Categories: … Serotonin Agents ... Serotonin Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists …

CR002

CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Vestronidase alfa

Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Spheramine

Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …

Autologous cord blood

Investigational
Matched Synonyms: … Autologous human umbilical cord blood …

Simvastatin

Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Description: … belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... studies to significantly reduce the risk of development of CVD and all-cause mortality. ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and ezetimibe ... sitagliptin and simvastatin ... simvastatin and fenofibrate ... simvastatin and acetylsalicylic acid ... simvastatin, acetylsalicylic acid and ramipril …
Matched Products: … SIMVASTATIN 1A PHARMA 5MG ... SIMVASTATIN 1A PHARMA 10MG ... SIMVASTATIN 1A PHARMA 20MG …

Alunacedase alfa

Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Investigational
Matched Synonyms: … Recombinant Human Angiotensin-Converting Enzyme 2 …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

Seviprotimut-L

Seviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and III Melanoma Patients).
Investigational
Matched Synonyms: … Human polyvalent shedded antigen vaccine …
Matched Description: … is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and …

FOV 2501

Investigational
Matched Synonyms: … Recombinant human rod-derived cone viability factor …
Displaying drugs 1001 - 1025 of 1390 in total