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Displaying drugs 10401 - 10425 of 13521 in total
Sofalcone is a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori. on adherence, production of vacuolating toxin (VT), and induction of interleukin-8 (IL-8) secretion by H. pylori.
Investigational
Matched Iupac: … 2-{5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy …
Matched Description: … Sofalcone is a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. Custirsen is also being investigated in...
Investigational
Matched Description: … Custirsen is a benzopyran with potential antineoplastic activity. ... This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent ... Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an...
Investigational
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Investigational
Matched Iupac: … 4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-1H-indazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
LFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection.
Investigational
Matched Iupac: … {12,15}.1^{19,22}.1^{26,29}.0^{6,11}]tritetraconta-1(38),2(43),4,6,8,10,12(42),14,19(41),21,26(40),28,36 ... (39)-tridecaen-8-yl]-1,3-thiazol-4-yl})carbamoyl]oxy}cyclohexane-1-carboxylic acid ... (propan-2-yl)-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decaazaheptacyclo[34.2.1.1^{2,5}.1^ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine and amphetamine in the body and can lead to positive tests results for illicit drug use.[A236369,L34724] Famprofazone is included in...
Experimental
Matched Iupac: … 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol …
Matched Description: … Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Investigational
Matched Synonyms: … AKCEA-APO(a)-LRx ... IONIS-APO(a)-LRx ... Isis-681257 (galnac3--conjugated aso targeting human lipoprotein (a)) free acid …
Matched Description: … -lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease). ... Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a) …
Experimental
Matched Iupac: … methyloxan-2-yl]oxy}-2-ethyl-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1- …
Experimental
Matched Synonyms: … Acetoacetyl coenzyme A ... Acetoacetyl-Coenzyme A ... S-Acetoacetyl-coenzym A
Matched Categories: … Thioesters of coenzyme A
Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no...
Investigational
Matched Description: … A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. ... It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle ... It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. …
Experimental
Vet approved
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Experimental
Experimental
Experimental
Matched Iupac: … 2-methyl-1-(nitrooxy)-2-[(nitrooxy)methyl]pentane …
Displaying drugs 10401 - 10425 of 13521 in total