Displaying drugs 10626 - 10650 of 12570 in total
Padsevonil
Padsevonil is under investigation in clinical trial NCT03695094 (A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil).
Investigational
Matched Iupac: … (4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Centhaquine
Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock).
Investigational
Matched Iupac: … 2-{2-[4-(3-methylphenyl)piperazin-1-yl]ethyl}quinoline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE
Experimental
Matched Name: … (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
Bekanamycin
Experimental
Matched Iupac: … (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino ... -3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4-diol …
D-gluconhydroximo-1,5-lactam
Experimental
11-MERCAPTOUNDECANOIC ACID
Experimental
Natural Killer Cell
Natural Killer (NK) cells originate and differentiate from hematopoietic stem cells through various signalling pathways involving cytokines and interleukins. These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral blood. Once completely differentiated, NK cells lack B (CD19-) and T(CD3-) lymphocyte markers and carry...
Investigational
Matched Description: … These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral …
BI-836826
Investigational
N-[3-(aminomethyl)benzyl]acetamidine
Experimental
Matched Name: … N-[3-(aminomethyl)benzyl]acetamidine …
Matched Iupac: … N-{[3-(aminomethyl)phenyl]methyl}ethanimidamide …
Matched Iupac: … N-{[3-(aminomethyl)phenyl]methyl}ethanimidamide …
(2S)-2-Methyl-3-phenylpropanoic acid
Experimental
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
N-(3-AMINOPROPYL)-2-NITROBENZENAMINE
Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
K-00546
Experimental
Matched Iupac: … 5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide …
B7-H3-specific chimeric antigen receptor T cells
Investigational
Rilapladib
Rilapladib is the third genomics-derived small molecule drug arising from the Human Genome Sciences-GlaxoSmithKline collaboration to enter clinical development. It is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques.
Investigational
Matched Iupac: … 2-(2-{[(2,3-difluorophenyl)methyl]sulfanyl}-4-oxo-1,4-dihydroquinolin-1-yl)-N-[1-(2-methoxyethyl)piperidin ... -4-yl]-N-{[4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]methyl}acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Guanosine-3'-monophosphate-5'-diphosphate
Experimental
Matched Synonyms: … Guanosine 3'-(dihydrogen phosphate) 5'-(trihydrogen diphosphate) …
Matched Name: … Guanosine-3'-monophosphate-5'-diphosphate …
Matched Iupac: … {[hydroxy({[(2R,3S,4R,5R)-4-hydroxy-5-(6-hydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-(phosphonooxy)oxolan …
Matched Name: … Guanosine-3'-monophosphate-5'-diphosphate …
Matched Iupac: … {[hydroxy({[(2R,3S,4R,5R)-4-hydroxy-5-(6-hydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-(phosphonooxy)oxolan …
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol
Experimental
Matched Name: … 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE
Experimental
Matched Name: … 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE …
Matched Iupac: … (2S)-2-amino-3-[4-(2,2,2-trifluoroethyl)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[4-(2,2,2-trifluoroethyl)phenyl]propanoic acid …
Troxacitabine
Troxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
Investigational
Matched Iupac: … 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
OPC-51803
OPC-51803 is the first nonpeptide vasopressin (AVP) V(2)-receptor-selective agonist. It is a V(2)-selective agonist that produces a significant antidiuretic action after single and multiple oral dosing in AVP-deficient and normal AVP states. It is useful therapeutic drug in the treatment of hypothalamic diabetes insipidus, nocturnal enuresis, and some kinds of...
Investigational
Matched Iupac: … 2-[(5R)-1-[2-chloro-4-(pyrrolidin-1-yl)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N-(propan-2- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Varlitinib
Varlitinib is an oral, selective, reversible, small molecule tyrosine kinase inhibitor of both ErbB-2 (Her-2/neu) and EGFR. Over-expression of ErbB-2 and EGFR receptors in tumors is predictive of poor prognosis in cancer patients. Varlitinib has shown significant anti-tumor activity in preclinical models of human breast, lung, and epidermal carcinoma tumors.
Investigational
Matched Iupac: … N4-{3-chloro-4-[(1,3-thiazol-2-yl)methoxy]phenyl}-N6-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]quinazoline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Narasin
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Iupac: … {5}]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3,5-dimethyloxan-2-yl]butanoic acid ... 6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5^{7}.3^ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Obatoclax
Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.
Investigational
Matched Iupac: … 2-[(2Z)-2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Oxaflozane
Experimental
Matched Iupac: … 4-(propan-2-yl)-2-[3-(trifluoromethyl)phenyl]morpholine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10626 - 10650 of 12570 in total