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Displaying drugs 10726 - 10750 of 11603 in total
Evacetrapib
Evacetrapib has been used in trials studying the basic science and treatment of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Hepatic Insufficiency, and Cardiovascular Disease.
Investigational
Matched Iupac: … (1r,4r)-4-{[(5S)-5-({[3,5-bis(trifluoromethyl)phenyl]methyl}(2-methyl-2H-1,2,3,4-tetrazol-5-yl)amino) ... -7,9-dimethyl-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]methyl}cyclohexane-1-carboxylic acid …
Bicifadine
Bicifadine (DOV-220075) is a nonopioid analgesic. It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile. Bicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain.
Investigational
Matched Iupac: … 1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane …
Matched Salts cas: … 66504-75-4 …
Matched Salts cas: … 66504-75-4 …
Cloridarol
Cloridarol is an experimental medication in the treatment of heart disease, which acts through vasodilation. It was studied for the treatment of coronary insufficiency in Italy in the 1970s .
Experimental
Matched Iupac: … (1-benzofuran-2-yl)(4-chlorophenyl)methanol …
Ovalicin
Experimental
Matched Iupac: … (2S,3R,4R)-3,4-dihydroxy-2-methoxy-4-methyl-3-[(2S,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl] ... cyclohexan-1-one …
Managlinat dialanetil
CS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.
Investigational
Matched Iupac: … ethyl (2S)-2-[({5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}({[(2S)-1-ethoxy-1-oxopropan …
PF-06882961
PF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl …
Zilurgisertib
Investigational
Matched Iupac: … 2-amino-N-{4-hydroxybicyclo[2.2.2]octan-1-yl}-5-{4-[(1R,5S)-3-(oxan-4-yl)-3-azabicyclo[3.1.0]hexan-1- …
Acyline
Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception.
Investigational
Matched Iupac: … (2S)-N-[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino ... )propanamido]-3-(4-acetamidophenyl)propanamido]-4-methylpentanamide ... -2-yl)propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]-3-(4-acetamidophenyl ... ]hexan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-(4-chlorophenyl)-2-[(2R)-2-acetamido-3-(naphthalen …
(South)-Methanocarba-Thymidine
Experimental
Matched Iupac: … 1-[(1S,3S,4R,5S)-3-hydroxy-4-(hydroxymethyl)bicyclo[3.1.0]hexan-1-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine …
Tipifarnib
Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. It is also called Zarnestra. In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.
Investigational
Matched Iupac: … 6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-1,2-dihydroquinolin …
Cafedrine
Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Investigational
Matched Iupac: … 7-(2-{[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino}ethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6 …
Nidufexor
Nidufexor is under investigation in clinical trial NCT03804879 (Safety, Tolerability and Efficacy of LMB763 in Patients With Diabetic Nephropathy).
Investigational
Matched Iupac: … 4-[(N-benzyl-1-{8-chloro-1-methyl-1H,4H-chromeno[4,3-c]pyrazol-3-yl}formamido)methyl]benzoic acid …
TNP-2092
TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).
Investigational
Matched Iupac: … -1-yl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid ... 28),2,4,9,19,21,25(29),26-octaen-26-yl]methylidene}amino]piperidin-4-yl}(methyl)amino)cyclopropyl]pyrrolidin ... 8-[(3R)-3-[1-({1-[(E)-{[(7S,9E,11S,12S,13S,14S,15R,16R,17S,18S,19E)-13-(acetyloxy)-2,15,17,27,29-pentahydroxy ... 3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1( …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Filaminast
Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Experimental
Matched Iupac: … (E)-{1-[3-(cyclopentyloxy)-4-methoxyphenyl]ethylidene}amino carbamate …
Matched Description: … Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). …
Matched Description: … Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). …
Tetra(Imidazole)Diaquacopper (Ii)
Experimental
Matched Iupac: … lambda4-copper(4+) tetrakis(1H-imidazol-1-ide) dihydrate …
2-Chloro-6-Methyl-Aniline
Experimental
Matched Iupac: … (1S)-2-methyl-6-methylidenecyclohexa-2,4-dien-1-amine …
Amitifadine
Investigational
Matched Iupac: … (1R,5S)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane …
(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE
Experimental
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
T-62
T-62 has been used in trials studying the treatment of Postherpetic Neuralgia.
Investigational
Matched Iupac: … 3-(4-chlorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine …
Displaying drugs 10726 - 10750 of 11603 in total