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Displaying drugs 11226 - 11250 of 13481 in total

Vonlerolizumab

Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational

Telapristone acetate

Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Iupac: … (1R,3aS,3bS,10R,11aS)-10-[4-(dimethylamino)phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH, …

Florfenicol

Florfenicol is a fluorinated synthetic analog of thiamphenicol.
Experimental
Vet approved
Matched Iupac: … 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide …

QXL138AM

QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational

Tulobuterol

Tulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 2-(tert-butylamino)-1-(2-chlorophenyl)ethan-1-ol …
Matched Categories: … Selective Beta 2-adrenergic Agonists …

Nitroaspirin

Nitroaspirin has been investigated for the treatment of Intermittent Claudication.
Investigational
Matched Iupac: … 3-[(nitrooxy)methyl]phenyl 2-(acetyloxy)benzoate …
Matched Categories: … Non COX-2 selective NSAIDS …

Difenpiramide

Experimental
Matched Iupac: … 2-{[1,1'-biphenyl]-4-yl}-N-(pyridin-2-yl)acetamide …
Matched Categories: … Non COX-2 selective NSAIDS …

Theobromine

Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no...
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Leupeptin

Investigational
Matched Synonyms: … L-leucinamide, n-acetyl-l-leucyl-n-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (s)- …
Matched Iupac: … (2S)-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}-3-methylbutyl]-2-acetamido-4-methylpentanamide …

AOC 1001

AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational

Mirococept

Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational

Acetylleucine

Used for treating vestibular-related imbalance and vertigo.
Experimental
Matched Synonyms: … (R,S)-N-Acetylleucin …
Matched Iupac: … 2-acetamido-4-methylpentanoic acid …

Ananain

Investigational

Z-Pro-Prolinal

Experimental
Matched Iupac: … benzyl (2S)-2-[(2S)-2-formylpyrrolidine-1-carbonyl]pyrrolidine-1-carboxylate …

VX-702

VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …

1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide

Experimental
Matched Iupac: … (2S)-1-butanoyl-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide …

N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide

Experimental
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide …

BMS-394136

BMS-394136 has been used in trials studying the diagnostic of Heart Diseases.
Investigational
Matched Iupac: … (2S)-1-[(7R)-7-(3,4-dichlorophenyl)-5-methyl-4H,7H-pyrazolo[1,5-a]pyrimidine-6-carbonyl]-2-(4-fluorophenyl …

Aminopentamide

Experimental
Vet approved
Matched Salts cas: … 2019-75-2 …

Willardiine

Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental

Apomorphine palmitate

Investigational
Matched Iupac: … (9R)-4-(hexadecanoyloxy)-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,13,15 …

Bizaxofusp

Investigational

Umbilical Cord Blood Hematopoietic Stem Cells

The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive collection procedures, and more plasticity for multi-differentiation. UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have increased sensitivity to various factors, and are able to...
Investigational

5-beta-D-ribofuranosylnicotinamide adenine dinucleotide

Experimental
Matched Name: … 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide …
Matched Iupac: … 3-[(2S,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy ... )phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-5-carbamoylpyridin-1-ium …

7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate)

Experimental
Matched Name: … 7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate) …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-6,7,8,9-tetrahydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2 …
Displaying drugs 11226 - 11250 of 13481 in total