Displaying drugs 11376 - 11400 of 15403 in total
IMMU-114
IMMU-114 is antibody-drug conjugate consisting of humanized anti-HLA-DR IgG4 monoclonal antibody specific for alpha-chain linked to SN-38 via a CL2A linker.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nofazinlimab
Nofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ichorcumab
Ichorcumab is under investigation in clinical trial NCT03251482 (A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery).
Investigational
Matched Description: … Ichorcumab is under investigation in clinical trial NCT03251482 (A Study to Evaluate the Safety and Efficacy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Danburstotug
Danburstotug is under investigation in clinical trial NCT04809012 (Study of STI-3031 in Patients With Selected Relapsed or Refractory Solid Tumors).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Eldelumab
MDX-1100, a fully human antibody that targets IP10 (also known as CXCL10), a chemokine expressed in association with multiple inflammatory disease indications, such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.
Investigational
Matched Description: … multiple inflammatory disease indications, such as rheumatoid arthritis, inflammatory bowel disease and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Patritumab
Patritumab has been used in trials studying the treatment of LUNG CANCER, Solid Tumors, Neoplasms by Site, Head and Neck Neoplasms, and Non-small Cell Lung Cancer, among others.
Investigational
Matched Description: … Neck Neoplasms, and Non-small Cell Lung Cancer, among others. ... has been used in trials studying the treatment of LUNG CANCER, Solid Tumors, Neoplasms by Site, Head and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Fletikumab
Fletikumab is under investigation in clinical trial NCT01038674 (Safety and Tolerability of Anti-IL-20 in Subjects With Rheumatoid Arthritis).
Investigational
Matched Description: … Fletikumab is under investigation in clinical trial NCT01038674 (Safety and Tolerability of Anti-IL-20 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mavrilimumab
Mavrilimumab has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Malacidin A
Malacidin A, along with DB14052, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin A...
Experimental
Matched Iupac: … 1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3-[(2E,4Z)-8-methylnona-2,4-dienamido]propanoic acid …
Matched Description: … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears ... Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears ... Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Malacidin B
Malacidin B, along with DB14051, is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria . Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. While structurally similar to other macrocycle drugs like DB00080 and DB06087, Malacidin B...
Experimental
Matched Iupac: … 1,4,7,10,13,16,19,22,25-nonaazacyclooctacosan-4-yl]carbamoyl}-2-methyl-3-[(2E,4Z)-8-methyldeca-2,4-dienamido]propanoic acid …
Matched Description: … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears ... Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears ... Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis …
Matched Categories: … Amino Acids, Peptides, and Proteins …
GP-100 antigen
GP-100 antigen is under investigation in clinical trial NCT00006385 (Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Utomilumab
Utomilumab is under investigation in clinical trial NCT03318900 (T Cell Immunotherapy for Advanced Ovarian Cancer).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Suvratoxumab
Suvratoxumab is under investigation in clinical trial NCT02296320 (Study of the Efficacy and Safety of MEDI4893).
Investigational
Matched Description: … Suvratoxumab is under investigation in clinical trial NCT02296320 (Study of the Efficacy and Safety of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bleselumab
Bleselumab is under investigation in clinical trial NCT02921789 (Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients).
Investigational
Matched Description: … Bleselumab is under investigation in clinical trial NCT02921789 (Study to Assess the Efficacy and Safety …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
INH-A21
INH-A21 is a human staphylococcal immunoglobulin
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hemoglobin glutamer-250 (bovine)
Hemoglobin glutamer-250 (bovine) is under investigation in clinical trial NCT00300040 (Safety/feasibility Study of HBOC-201 in Amputation At/below Knee From Critical Lower Limb Ischemia).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Clobutinol
Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.
Withdrawn
Matched Description: … Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. …
Matched Categories: … Cough and Cold Preparations …
Matched Categories: … Cough and Cold Preparations …
Ligelizumab
Ligelizumab is a humanized IgG1k monoclonal antibody targeted against immunoglobulin E (IgE). Similar in mechanism to omalizumab, another IgE-directed monoclonal antibody, ligelizumab has a distinct binding epitope as compared to its peer (with a small degree of overlap) which appears to confer a greater affinity for free serum IgE and...
Investigational
Matched Description: … peer (with a small degree of overlap) which appears to confer a greater affinity for free serum IgE and ... While the precise pathogenesis of CSU is not entirely clear, autoantibodies against IgE receptors, and ... sometimes against IgE itself, are thought to exist in 30-40% of patients,[A242362,A242367] and the efficacy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ulocuplumab
Ulocuplumab is under investigation in Solid Tumor.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dusigitumab
Dusigitumab has been used in trials studying the treatment of Cancer, Advanced Solid Malignancies, Unresectable or Metastatic Hepatocellular Carcinoma (HCC), and Hormone-sensitive, HER-2 Negative Metastatic Breast Cancer.
Investigational
Matched Description: … of Cancer, Advanced Solid Malignancies, Unresectable or Metastatic Hepatocellular Carcinoma (HCC), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
EpiVacCorona
EpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in Russia, is based on peptide-antigens that facilitate immunity to the SARS-CoV-2 virus . It is currently being tested in Phase I/II clinical trials for safety and immunogenicity (NCT04527575)[L30608, L30613].
Investigational
Matched Description: … EpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in ... It is currently being tested in Phase I/II clinical trials for safety and immunogenicity (NCT04527575 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 11376 - 11400 of 15403 in total