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Displaying drugs 1151 - 1175 of 1642 in total
Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(multiple sclerosis-associated retrovirus viral envelope protein) (human-mus ... musculus monoclonal gnbac1 heavy chain), disulfide with human-mus musculus monoclonal gnbac1 kappa-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... A2359, A2360, A44] Due to its duration of action, Levemir is considered "basal insulin" as it provides low ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Investigational
Matched Synonyms: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Matched Name: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Synonyms: … Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human SLC6A3 gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 2 containing the human SLC6A3 gene …
Matched Description: … investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human
Experimental
Matched Synonyms: … L-gamma-Glutamyl hydroxamate ... L-glutamic acid γ-hydroxamic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-γ-L-glutamyl}-L-glutamate …
Matched Categories: … Enzymes and Coenzymes …
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TEKAN-L 4 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON …
Investigational
Matched Synonyms: … transforming growth factor beta receptor type II linked to a human IgG1 Fc domain ... Homodimeric fragment crystallizable fusion protein comprised of the extracellular domain of the human
Investigational
Matched Name: … Humate-P …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … "), and very-low-density lipoprotein (VLDL). ... levels and CVD risk. ... Bruce Roth and approved by the FDA in 1996. …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine and atorvastatin ... Amlodipine and atorvastatin …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …
Matched Products: … COLASTIN-L 10 MG FILM KAPLI TABLET, 30 ADET ... COLASTIN-L 10 MG FILM KAPLI TABLET, 90 ADET ... COLASTIN-L 20 MG FILM KAPLI TABLET, 30 ADET …
Experimental
Matched Name: … TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE …
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c4g7 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c4g7 heavy chain), disulfide …
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … MFSD8 gene for expression of active human major facilitator superfamily domain containing 8 ... An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/ …
Matched Description: … CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. ... It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human
Experimental
Matched Name: … N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alanyl-L-alaninamide …
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. ... It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immune Globulin (Human) containing high titers of West Nile virus antibodies …
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 9 (AAV9) containing human RPE65 gene …
Experimental
Matched Name: … L-methionine (R)-S-oxide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … L-methionine (S)-S-oxide …
Experimental
Matched Name: … (4s)-5-Fluoro-L-Leucine …
Displaying drugs 1151 - 1175 of 1642 in total