Displaying drugs 1176 - 1200 of 1620 in total
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4-c)pyrrol-2(1h)-yl)-3-hydroxy-2-phenyl …
Atenolol
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions.
Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Synonyms: … 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide …
Matched Iupac: … 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Beta Blocking Agents and Thiazides ... atenolol and thiazides ... atenolol and nifedipine ... atenolol and other diuretics ... Beta blocking agents and calcium channel blockers …
Matched Iupac: … 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Beta Blocking Agents and Thiazides ... atenolol and thiazides ... atenolol and nifedipine ... atenolol and other diuretics ... Beta blocking agents and calcium channel blockers …
NM-004
Investigational
Matched Synonyms: … 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid …
Asundexian
Asundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke).
Investigational
Matched Synonyms: … pyridineacetamide, n-(4-(aminocarbonyl)-3-fluorophenyl)-4-(5-chloro-2-(4-(trifluoromethyl)-1h-1,2,3-triazol-1-yl)phenyl …
1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID
Experimental
Matched Name: … 1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID …
6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine
Experimental
Matched Name: … 6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoylnaphthalene-2-carboxamide …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoylnaphthalene-2-carboxamide …
beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide
Experimental
Matched Name: … beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide …
1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine
Experimental
Matched Name: … 1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine …
Matched Iupac: … N''-[4-(2-oxo-2-phenylethyl)phenyl]guanidine …
Matched Iupac: … N''-[4-(2-oxo-2-phenylethyl)phenyl]guanidine …
PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE
Experimental
Matched Name: … PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE …
Matched Iupac: … 2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole …
Matched Iupac: … 2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole …
2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide
Experimental
Matched Name: … 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide …
Matched Iupac: … 2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide …
Matched Iupac: … 2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide …
4-(4-CHLORO-PHENYL)-1-{3-[2-(4-FLUORO-PHENYL)-[1,3]DITHIOLAN-2-YL]-PROPYL}-PIPERIDIN-4-OL
Experimental
Matched Name: … 4-(4-CHLORO-PHENYL)-1-{3-[2-(4-FLUORO-PHENYL)-[1,3]DITHIOLAN-2-YL]-PROPYL}-PIPERIDIN-4-OL …
Elzasonan
Elzasonan is under investigation in clinical trial NCT00275197 (A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)).
Investigational
Matched Synonyms: … 3-thiomorpholinone, 4-(3,4-dichlorphenyl)-2-((2-(4-methyl-1-piperazinyl) phenyl)methylene)-, (2z)- …
Carbinoxamine
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and...
Approved
Matched Synonyms: … {2-[(4-Chloro-phenyl)-pyridin-2-yl-methoxy]-ethyl}-dimethyl-amine …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... uses (including management of congestion, cough, the common cold, and the use in children under 2 years …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... uses (including management of congestion, cough, the common cold, and the use in children under 2 years …
Pioglitazone
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Synonyms: … (±)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione …
Matched Iupac: … 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … [L11416] The thiazolidinedione class of medications, which also includes [rosiglitazone] and [troglitazone ... Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications ... affect numerous metabolic processes, most notably lipid and glucose homeostasis. …
Matched Mixtures name: … Pioglitazone and metformin ... Pioglitazone and Metformin Hydrocholride ... Pioglitazone and Metformin Hydrocholride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Iupac: … 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Matched Description: … [L11416] The thiazolidinedione class of medications, which also includes [rosiglitazone] and [troglitazone ... Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications ... affect numerous metabolic processes, most notably lipid and glucose homeostasis. …
Matched Mixtures name: … Pioglitazone and metformin ... Pioglitazone and Metformin Hydrocholride ... Pioglitazone and Metformin Hydrocholride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Sunvozertinib
Sunvozertinib is under investigation in clinical trial NCT03974022 (Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)).
Investigational
Matched Synonyms: … N-{5-[(4-{[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino}pyrimidin-2-yl)amino]-2-[(3R)-3- …
3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
Experimental
Matched Name: … 3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE …
Matched Iupac: … 3-chloro-2,2-dimethyl-N-[4-(trifluoromethyl)phenyl]propanamide …
Matched Iupac: … 3-chloro-2,2-dimethyl-N-[4-(trifluoromethyl)phenyl]propanamide …
[4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID
Experimental
Matched Name: … [4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID …
3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol
Experimental
Matched Name: … 3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol …
Matched Iupac: … 3-{[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]amino}phenol …
Matched Iupac: … 3-{[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]amino}phenol …
Florbetaben F-18
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Synonyms: … 4-((1E)-2-(4-(2-(2-(2-((SUP 18(F))FLUOROETHOXY)ETHOXY)ETHOXY)PHENYL)ETH-1-EN-1-YL)-N-METHYLANILINE …
Matched Iupac: … 4-[(E)-2-[4-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)phenyl]ethenyl]-N-methylaniline …
Matched Iupac: … 4-[(E)-2-[4-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)phenyl]ethenyl]-N-methylaniline …
HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM
Experimental
Matched Name: … HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM …
Matched Iupac: … (2Z)-N-(3-nitrophenyl)-4-{3-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}-2,5-dihydropyrimidin-2-imine …
Matched Iupac: … (2Z)-N-(3-nitrophenyl)-4-{3-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}-2,5-dihydropyrimidin-2-imine …
(2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL
Experimental
Matched Name: … (2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY …
Matched Iupac: … (2R)-1-(dimethylamino)-3-{4-[(6-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]phenoxy …
Matched Iupac: … (2R)-1-(dimethylamino)-3-{4-[(6-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]phenoxy …
3-amino-1-chloro-4-phenyl-butanol-2-yl
Experimental
Matched Name: … 3-amino-1-chloro-4-phenyl-butanol-2-yl …
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE
Experimental
Matched Name: … 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE …
2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid
Metabolic product of biphenyl; from Pseudomonas putida.
Experimental
Matched Name: … 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid …
Ceforanide
Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Synonyms: … (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl] ... 7β-[2-(aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham …
Matched Iupac: … (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …
Matched Description: … Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ... ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species …
Matched Iupac: … (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …
Matched Description: … Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ... ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species …
Displaying drugs 1176 - 1200 of 1620 in total