Displaying drugs 12226 - 12250 of 12994 in total
Garenoxacin
Garenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Investigational
Matched Iupac: … 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydroquinoline …
Fosdevirine
Investigational
Matched Iupac: … (S)-(methyl (2-carbamoyl-5-chloro-1H-indol-3-yl)({3-[(1E)-2-cyanoeth-1-en-1-yl]-5-methylphenyl})phosphinate …
Clocapramine
Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia. In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. Clocapramine has been implicated in at least one strange death,...
Experimental
Matched Iupac: … 1'-(3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)-[1,4'-bipiperidine …
Eltanolone
Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone).
Investigational
Matched Iupac: … 1-[(1S,2S,5R,7R,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl ... ]ethan-1-one …
CHF-6001
CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … ium-1-olate ... )-4-(difluoromethoxy)phenyl]-2-[3-(cyclopropylmethoxy)-4-methanesulfonamidobenzoyloxy]ethyl]pyridin-1- …
MK-2225
Investigational
N-chlorotaurine
N-chlorotaurine is an inhibitor of inducible nitric oxide synthase and IkappaB kinase.
Investigational
Matched Iupac: … 2-(chloroamino)ethane-1-sulfonic acid …
Cyclopentamine
Cyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. It has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.
Withdrawn
Matched Iupac: … (1-cyclopentylpropan-2-yl)(methyl)amine …
Butonate
Experimental
Vet approved
Matched Iupac: … 2,2,2-trichloro-1-(dimethoxyphosphoryl)ethyl butanoate …
Myxopyronin B
Experimental
Matched Iupac: … methyl N-[(1E)-5-{3-[(2E,4E)-2,5-dimethylnona-2,4-dienoyl]-4-hydroxy-2-oxo-2H-pyran-6-yl}pent-1-en-1- …
LY-3039478
LY3039478 has been used in trials studying the treatment and basic science of LYMPHOMA, Neoplasms, Solid Tumor, COLON CANCER, and BREAST CANCER, among others.
Investigational
Matched Iupac: … 1(15),2,4,6,11,13-hexaen-10-yl]carbamoyl}ethyl]butanamide ... 4,4,4-trifluoro-N-[(1S)-1-{[(10S)-8-(2-hydroxyethyl)-9-oxo-6,8-diazatricyclo[9.4.0.0^{2,7}]pentadeca- …
Refametinib
Investigational
Matched Iupac: … -1-sulfonamide ... N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[(2S)-2,3-dihydroxypropyl]cyclopropane …
AC-(D)PHE-PRO-BOROHOMOLYS-OH
Experimental
Matched Iupac: … [(1R)-6-amino-1-{[(2S)-1-[(2R)-2-acetamido-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}hexyl]boronic …
Clorotepine
Experimental
Matched Iupac: … 1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine …
AZD-0424
AZD0424 has been used in trials studying the treatment of Advanced Solid Tumours.
Investigational
Matched Iupac: … 1-[4-(2-{[4-({6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-yl}amino)-5-(propan-2-yloxy)quinazolin-7-yl]oxy ... }ethyl)piperazin-1-yl]ethan-1-one …
PF-06815345
PF-06815345 is under investigation in clinical trial NCT02654899 (Single Dose Study of PF-06815345 in Healthy Subjects).
Investigational
Matched Iupac: … -5-yl)-1H-1,2,3,4-tetrazol-1-yl]ethyl ethyl carbonate ... (1S)-1-[5-(4-{4-[(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl]-2-fluorophenyl}-1-methyl-1H-pyrazol …
Pecavaptan
Pecavaptan is under investigation in clinical trial NCT03901729 (A Trial to Study BAY1753011 in Patients With Congestive Heart Failure).
Investigational
Matched Iupac: … 3-(4-chlorophenyl)-1-{[1-(3-chlorophenyl)-5-[(1S)-1-hydroxyethyl]-1H-1,2,4-triazol-3-yl]methyl}-4-[(2S ... )-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-5-one …
Farnesol
A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th...
Experimental
Matched Iupac: … (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol …
Tosyl-D-Proline
Experimental
Matched Iupac: … (2R)-1-(4-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Methionine Phosphinate
Experimental
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphinic acid …
Butylphthalide
Butylphthalide has been used in trials studying the prevention of Restenosis.
Investigational
Matched Iupac: … 3-butyl-1,3-dihydro-2-benzofuran-1-one …
Displaying drugs 12226 - 12250 of 12994 in total