Displaying drugs 12251 - 12275 of 12799 in total
Heparin Disaccharide I-S
Experimental
Matched Iupac: … }-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate ... (2R,3R,4S)-2-{[(2R,3S,4R,5R,6S)-4,6-dihydroxy-5-(sulfonatoamino)-2-[(sulfonatooxy)methyl]oxan-3-yl]oxy …
TETRAHEDRAL INTERMEDIATE OF BLASTICIDIN S
Experimental
Matched Iupac: … (2S,3S,6R)-6-[(4S)-4-amino-4-hydroxy-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]-3-[(3S)-3-amino-5-(N-methylcarbamimidamido ... )pentanamido]-3,6-dihydro-2H-pyran-2-carboxylic acid …
1,6-Fructose Diphosphate (Linear Form)
Experimental
Matched Iupac: … {[(3S,4S,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
N-Propargyl-1(S)-Aminoindan
Experimental
Matched Iupac: … (1S)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Bimoclomol
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
Matched Iupac: … (Z)-N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carbonimidoyl chloride …
Minodronic acid
Investigational
Matched Iupac: … (1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosphonoethyl)phosphonic acid …
Lubazodone
Lubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was discontinued. It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist.
Experimental
Matched Iupac: … (2S)-2-{[(7-fluoro-2,3-dihydro-1H-inden-4-yl)oxy]methyl}morpholine …
Matched Salts cas: … 161178-10-5 …
Matched Salts cas: … 161178-10-5 …
Setiptiline
Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.
Experimental
Matched Iupac: … 4-methyl-4-azatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),2(7),8,10,12,15,17-heptaene …
Veledimex
Veledimex has been used in trials studying the treatment of Glioblastoma Multiforme, Metastatic Breast Cancer, and Anaplastic Oligoastrocytoma.
Investigational
Matched Iupac: … N'-(3,5-dimethylbenzoyl)-N'-[(3R)-2,2-dimethylhexan-3-yl]-2-ethyl-3-methoxybenzohydrazide …
Glyceryl Trierucate
Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.
Investigational
Matched Iupac: … 1,3-bis[(13Z)-docos-13-enoyloxy]propan-2-yl (13Z)-docos-13-enoate …
Mannosulfan
Experimental
Matched Iupac: … (2R,3S,4S,5R)-3,4-dihydroxy-1,5,6-tris(methanesulfonyloxy)hexan-2-yl methanesulfonate …
SUVN-G3031
SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).
Investigational
Matched Iupac: … N-{4-[(1-cyclobutylpiperidin-4-yl)oxy]phenyl}-2-(morpholin-4-yl)acetamide …
Penequinine, Penehyclidine
Penequinine, Penehyclidine is under investigation in clinical trial NCT02644876 (Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications).
Investigational
Matched Iupac: … 2-{1-azabicyclo[2.2.2]octan-3-yloxy}-1-cyclopentyl-1-phenylethan-1-ol …
PHA-767491
PHA-767491 is a Cdc7/CDK9 inhibitor.
Investigational
Matched Iupac: … 2-(pyridin-4-yl)-1H,6H,7H-pyrrolo[3,2-c]pyridin-4-ol …
Tolrestat
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was sold under the tradename...
Withdrawn
Matched Iupac: … 2-{1-[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-N-methylmethanethioamido}acetic acid …
7-Deaza-7-Aminomethyl-Guanine
Experimental
Matched Iupac: … 2-amino-5-(aminomethyl)-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one …
Beta-Hydroxytryptophane
Experimental
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(1H-indol-3-yl)propanoic acid …
7-Aza-L-tryptophan
Experimental
Matched Iupac: … (2S)-2-amino-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid …
Resatorvid
Resatorvid is an investigational compound designed for the treatment of severe sepsis.
Investigational
Matched Iupac: … ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate …
MLN576
XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.
Investigational
Matched Iupac: … N-[(2R)-1-(dimethylamino)propan-2-yl]-1-methoxy-5,10-diazatetraphene-6-carboxamide …
Anisomycin
Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
Experimental
Matched Iupac: … (2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl acetate …
5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Experimental
Matched Iupac: … 5-chloro-7-[(propan-2-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile …
Etifoxine
Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an...
Investigational
Withdrawn
Matched Iupac: … 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine …
Mepiprazole
Mepiprazole is a minor tranquilizer with a phenylpiperazine structure. It is a pyrazolyl-alkyl-piperazine derivative. Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons .
Mepiprazole is marketed in Spain for the treatment of anxiety neuroses.
It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and...
Experimental
Matched Iupac: … 1-(3-chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine …
Matched Salts cas: … 20344-15-4 …
Matched Salts cas: … 20344-15-4 …
Niludipine
Niludipine is a calcium channel blocker.
Experimental
Matched Iupac: … 3,5-bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Displaying drugs 12251 - 12275 of 12799 in total