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Displaying drugs 12401 - 12425 of 12868 in total
1,6-Fructose Diphosphate (Linear Form)
Experimental
Matched Iupac: … {[(3S,4S,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
N-Propargyl-1(S)-Aminoindan
Experimental
Matched Iupac: … (1S)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline
Experimental
Matched Iupac: … (2R)-2-amino-3-({[(1,10-phenanthrolin-5-yl)carbamoyl]methyl}sulfanyl)propanoic acid …
Bimoclomol
Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.
Investigational
Matched Iupac: … (Z)-N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carbonimidoyl chloride …
Minodronic acid
Investigational
Matched Iupac: … (1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosphonoethyl)phosphonic acid …
Lubazodone
Lubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was discontinued. It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist.
Experimental
Matched Iupac: … (2S)-2-{[(7-fluoro-2,3-dihydro-1H-inden-4-yl)oxy]methyl}morpholine …
Matched Description: … It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. …
Matched Salts cas: … 161178-10-5 …
Matched Description: … It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. …
Matched Salts cas: … 161178-10-5 …
Setiptiline
Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.
Experimental
Matched Iupac: … 4-methyl-4-azatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),2(7),8,10,12,15,17-heptaene …
Matched Salts cas: … 85650-57-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Salts cas: … 85650-57-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Glyceryl Trierucate
Glyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.
Investigational
Matched Iupac: … 1,3-bis[(13Z)-docos-13-enoyloxy]propan-2-yl (13Z)-docos-13-enoate …
Brovanexine
Experimental
Matched Iupac: … 4-[(2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}phenyl)carbamoyl]-2-methoxyphenyl acetate …
Matched Salts cas: … 54340-60-2 …
Matched Salts cas: … 54340-60-2 …
Deferitrin
Deferitrin is under investigation in clinical trial NCT00069862 (Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-thalassemia).
Investigational
Matched Iupac: … (4S)-2-(2,4-dihydroxyphenyl)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid …
Penequinine, Penehyclidine
Penequinine, Penehyclidine is under investigation in clinical trial NCT02644876 (Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications).
Investigational
Matched Iupac: … 2-{1-azabicyclo[2.2.2]octan-3-yloxy}-1-cyclopentyl-1-phenylethan-1-ol …
PHA-767491
PHA-767491 is a Cdc7/CDK9 inhibitor.
Investigational
Matched Iupac: … 2-(pyridin-4-yl)-1H,6H,7H-pyrrolo[3,2-c]pyridin-4-ol …
LG-100268
LG-100268 is a retinoid X receptor (RXR) selective compound.
Experimental
Matched Iupac: … 6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid …
Tolrestat
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was sold under the tradename...
Withdrawn
Matched Iupac: … 2-{1-[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-N-methylmethanethioamido}acetic acid …
7-Deaza-7-Aminomethyl-Guanine
Experimental
Matched Iupac: … 2-amino-5-(aminomethyl)-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one …
Beta-Hydroxytryptophane
Experimental
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(1H-indol-3-yl)propanoic acid …
7-Aza-L-tryptophan
Experimental
Matched Iupac: … (2S)-2-amino-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanoic acid …
Resatorvid
Resatorvid is an investigational compound designed for the treatment of severe sepsis.
Investigational
Matched Iupac: … ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate …
Iclaprim
Investigational
Matched Iupac: … 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine …
Matched Salts cas: … 474793-41-4 …
Matched Salts cas: … 474793-41-4 …
Anisomycin
Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
Experimental
Matched Iupac: … (2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl acetate …
Etifoxine
Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an...
Investigational
Withdrawn
Matched Iupac: … 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine …
Mepiprazole
Mepiprazole is a minor tranquilizer with a phenylpiperazine structure. It is a pyrazolyl-alkyl-piperazine derivative. Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons .
Mepiprazole is marketed in Spain for the treatment of anxiety neuroses.
It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and...
Experimental
Matched Iupac: … 1-(3-chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine …
Matched Description: … Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816]. ... It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake …
Matched Salts cas: … 20344-15-4 …
Matched Description: … Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816]. ... It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake …
Matched Salts cas: … 20344-15-4 …
Ozagrel
Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.
Investigational
Matched Iupac: … (2E)-3-{4-[(1H-imidazol-1-yl)methyl]phenyl}prop-2-enoic acid …
Matched Salts cas: … 78712-43-3 …
Matched Salts cas: … 78712-43-3 …
Pruvanserin
Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders.
Investigational
Matched Iupac: … 7-{4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl}-1H-indole-3-carbonitrile …
Calcium pangamate
Experimental
Matched Iupac: … calcium bis((2R,3S,4R,5R)-6-{[2-(dimethylamino)acetyl]oxy}-2,3,4,5-tetrahydroxyhexanoate) …
Displaying drugs 12401 - 12425 of 12868 in total